<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24960

Description Uncharacterized protein
SequenceMSMMEVDQMPLADVVFVIEGSAINGAYINELKTNYILPTLEHFTTGSIDEREYLIAERFATLYGIVVYRTAANLLEPICSTYGPFLQPQKVMETIERLPLVGGGMESCAHMAEGFAAAHGCFDDFAKHRQMIDQTSVQRHCILICNSPPYQMPTTESWKYQGKTCEQLASMFNEQKINLSIIAPRKMPVLFKLFMKADGDQPITSKNYAKNIRHLVLLKGYSLKERAPSPNSMAAQMAAPNAAQAVAQQQQQQQPQNPAVQQQPGGGMPMDTNPAQQQQQQPQQGNPQQQQQVLNMNPMQQPQQQPGQNPQAGLLNPQQQQQLIQQQQQQQQQQNQFVPNQMQNPNFPGQNRWMYPNQPGQQRPPFMQGAGNVGQGGGMQLQQQQNPNSALISRINAPPPNQTVNSLQQQQQQAQQQQQQQQQVQQQQQQRMQMISQQQILNHQQMQQQQQLAQQQQQQQQGQQQQGNPNNPGNNMMPAVSNAGNMPNPQQQQQQQQVGQQANPQQQGNPQQQQQANPQQEQASLREKIWTGILEWSEKPKSDQQKIPHTLQCTVCTNIKDGEPEIKAENWPPKLLMQLMPKHLVGNIGGQFLKDSKMVVFRPTPGEALDSLAKMMTSGYAGCVHFSSIPNSPACELKVLILLYTPDRNAFLGFIPNNQAMFVERLRKVIQQKQHGSMQQQQQQQQQQMLQQQGKSPMELQQQQQQQQQQQQMQQDNSQQQQQHYNQYQMNMQMGGGGPGGGPGPGGMPMQQNQMQMNMMQQQQRMPLGVGPGGVPNPNLQQQLQQVAPNVAAMQQQQQAQQQQRMVRPMMSNNNPGLRQLLQHQNTPVNQFRPQMGGQNPNQMGAGGPMVGNRNFDDGSYEFM
Length864
PositionUnknown
OrganismDrosophila ananassae (Fruit fly)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Brachycera> Muscomorpha> Ephydroidea> Drosophilidae> Drosophila> Sophophora.
Aromaticity0.05
Grand average of hydropathy-0.955
Instability index66.24
Isoelectric point8.76
Molecular weight97425.80
Publications
PubMed=17994087

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24960
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.53|      19|      26|     270|     292|       3
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  277-  300 (39.46/ 9.84)	QQQQQPQQGNPQQQqqvlnMNPMQ
  494-  512 (39.06/ 6.08)	QQQQVGQQANPQQQ.....GNPQQ
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     367.49|      69|      79|     694|     772|       4
---------------------------------------------------------------------------
  326-  389 (83.50/10.03)	..................Q...........................QQQQ..QQQQN...QfvpnQMQNPNF...PGQNRWMYP..NQPGQQrppfMQGAGNV.GQG.GGMQLQQQQNPNS
  390-  487 (77.27/13.14)	ALIsrinapPPNQTVNsLQqqqqqaqqqqqqqqqvqqqqqqrmqmiSQQQilNHQQM...Q....Q.QQQLA...QQQQQ...Q..QQGQQQ......QGNP.NNPGNNMMPAVSNAGNMP
  689-  758 (136.95/24.77)	MLQ.....qQGKSPME.LQ...........................QQQQ..QQQQQ...Q....QMQQDNS...QQQQQHYNQ..YQMNMQ....MGGGGPGGGPGPGGMPMQQNQMQMN
  792-  854 (69.78/ 6.85)	..............AA.MQ...........................QQQQ..AQQQQrmvR....PMMSNNNpglRQLLQHQNTpvNQFRPQ....MGGQNP.NQMGAGG.PMVGNR....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     248.01|      80|     115|      35|     117|       7
---------------------------------------------------------------------------
   35-  117 (129.74/99.54)	YILPTLE..HFTTGSIDEREYLIAERFATLyGIVVYRTAANLLEPICSTYGPflQP...QKVMETIERLPLVGG.GMESCAH....MAEGFAA
  150-  239 (118.27/79.48)	YQMPTTEswKYQGKTCEQLASMFNEQKINL.SIIAPRKMPVLFKLFMKADGD..QPitsKNYAKNIRHLVLLKGySLKERAPspnsMAAQMAA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     116.09|      30|      39|     576|     605|       8
---------------------------------------------------------------------------
  549-  581 (36.85/19.08)	HTLqctvCTNIkdGEPEIKAE.....N...WPPKL......LMQLMP
  582-  617 (42.90/23.33)	KHL....VGNI..GGQFLKDS.....KMVVFRPTPgealdsLAKMMT
  618-  656 (36.33/18.71)	SGY....AGCV..HFSSIPNSpacelKVLILLYTP..drnaFLGFIP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24960 with Med25 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KGYSLKERAPSPNSMAAQMAAPNAAQAVAQQQQQQQPQNPAVQQQPGGGMPMDTNPAQQQQQQPQQGNPQQQQQVLNMNPMQQPQQQPGQNPQAGLLNPQQQQQLIQQQQQQQQQQNQFVPNQMQNPNFPGQNRWMYPNQPGQQRPPFMQGAGNVGQGGGMQLQQQQNPNSALISRINAPPPNQTVNSLQQQQQQAQQQQQQQQQVQQQQQQRMQMISQQQILNHQQMQQQQQLAQQQQQQQQGQQQQGNPNNPGNNMMPAVSNAGNMPNPQQQQQQQQVGQQANPQQQGNPQQQQQANPQQEQASLREKIWTGILEWSEKPKSDQQKIPHTLQCT
2) RLRKVIQQKQHGSMQQQQQQQQQQMLQQQGKSPMELQQQQQQQQQQQQMQQDNSQQQQQHYNQYQMNMQMGGGGPGGGPGPGGMPMQQNQMQMNMMQQQQRMPLGVGPGGVPNPNLQQQLQQVAPNVAAMQQQQQAQQQQRMVRPMMSNNNPGLRQLLQHQNTPVNQFRPQMGGQNPNQMGAGGPMVGNRNFDDGSYEFM
219
665
554
864










Molecular Recognition Features






MoRF SequenceStartStop




NANANA