<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24910

Description Thyroid hormone receptor-associated protein complex 100 kDa component
SequenceMAWMTSTGCFDEVLTRGVSGDVYNLADCILQQAVVGSGANTLFLSYLKHSLCAHLISHAAVLKRIAKFEHLDRYHCMGELLDFLEQIIGGVTCRGKQEEGALTKAMLALVYWLMQIYEHALEVFSENNRALNSEQQLMVEKLGLVVEKLAQSQFLLGVVYVGKFEDPELYGLLVKKYELIDNLTAASGFVPPVVSQKNVTINDYLRKAALIDSDTLEMKEFDGRGIEPITYCLQPLIAIEILFNPNCDTQTYVAEFMSIQRLKGYTLSRLYCEIIRACLISLNNVNGTTRESFICAFTFIKVPHILRQIHMQSRLLNPTEYEETAKLDYSPEIVEAFELLLQDSPILDLMDARCACNTVECLLNEMLKNHLINEKQMKMIAARREQDTTGLQKLELNTNQHSIVKFVFRAEPPLVGILKTLGSDYNKVQEALLGMLLQVLSGNSFELILSVATVQGKLKTFISGLIKCNEASKQIPGEMGKVALARAALFDVSFLMLSFIVQSYGSEVVLAENGDSFFEKWVRECLVEKHKSKSPAVMVKLCDQNKVDELIVSLNSPEGLKGSSLKWHEICANIPGLLYQVLMAWENETLSTPEIKKFLDSLKSRFCCFSVCATSWLCAYMQVVRQDELLKPMNMVQQFLTAVSADELMQQENFKERLGLTVQIVRKMQQDFQRLPGTSPKLRTMLQSQNLVSQNPLEEQFEEVWKNVSERGWLPIDSTLVLENLLQSCGPFWLVDKLVQQIFHCKYIREMNKTMDIVFAIMHLDIERCTIALLSQLVPMMLLNKLQLSEIVDPFSRVLAKLCVYCIVATMEAPTGPLSKKRSRAAIDGDDLLADGLCPTPKMRKMGSDSCDSSSSDFMLEHAAAAAAAVAFATKEAASGGVSLREPLQGCLQTLFRTFAQYIVSDELSPKIYFMFQFLSLLVEVGRERVKPVLKLIPNGLVQSMLKINATDDMTVGFILRLYDLNATTGRTFAMSDLCLFRNIQMRKDSIKL
Length993
PositionTail
OrganismCulex quinquefasciatus (Southern house mosquito) (Culex pungens)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Culicinae> Culicini> Culex> Culex.
Aromaticity0.08
Grand average of hydropathy0.091
Instability index41.97
Isoelectric point5.78
Molecular weight111761.37
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP24910
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.99|      16|      39|     416|     431|       1
---------------------------------------------------------------------------
  416-  431 (28.12/19.23)	GILKTLGSDYNKVQEA
  456-  471 (28.87/19.93)	GKLKTFISGLIKCNEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.60|      37|      43|     227|     269|       2
---------------------------------------------------------------------------
  227-  269 (63.32/66.83)	EPITYCLQPliaieiLFNPNCDT.QTYVAEFMSIQR...LKGYTL.SR
  273-  314 (50.28/39.24)	EIIRACLIS......LNNVNGTTrESFICAFTFIKVphiLRQIHMqSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     136.32|      37|      41|     648|     688|       3
---------------------------------------------------------------------------
  622-  645 (25.87/13.83)	...............QVVR..QDELLKPM.NMVQQFLTAVSA
  648-  688 (56.08/55.31)	LMQQENFKERLgltvQIVRKMQQDFQRLP.GTSPKLRTMLQS
  691-  728 (54.38/42.00)	LVSQNPLEEQF....EEVWKNVSERGWLPiDSTLVLENLLQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.34|      22|      33|     137|     158|       4
---------------------------------------------------------------------------
  137-  158 (35.28/22.51)	LMVEKLGLVVEKLAQSQFLLGV
  172-  193 (37.06/24.00)	LLVKKYELIDNLTAASGFVPPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.65|      33|      47|     889|     927|       6
---------------------------------------------------------------------------
  889-  927 (46.34/42.55)	QGCLQTLFRTFAqyivSDELSpkIYFMFQFLSLLVEVGR
  939-  971 (55.31/33.01)	NGLVQSMLKINA....TDDMT..VGFILRLYDLNATTGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.58|      32|     375|      96|     127|       7
---------------------------------------------------------------------------
   96-  127 (57.31/48.33)	KQEEG.....ALTKAMLALVYWLMQ...IYEHALE.VFSEN
  473-  513 (39.27/30.24)	KQIPGemgkvALARAALFDVSFLMLsfiVQSYGSEvVLAEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     173.56|      49|     473|     325|     378|       8
---------------------------------------------------------------------------
  325-  378 (70.60/49.99)	AKL.DYSpeIVEAFEllLQDSPILDLMDARCACNTVeCLLNEMLKNHLINEKQMK
  761-  789 (34.98/13.79)	......................IMHLDIERC...TI.ALLSQLVPMMLLNKLQLS
  800-  844 (67.98/34.62)	AKLcVYC..IVATME..APTGP.LSKKRSRAAIDG.....DDLLADGLCPTPKMR
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP24910 with Med24 domain of Kingdom Metazoa

Unable to open file!