<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24910

Description Thyroid hormone receptor-associated protein complex 100 kDa component
SequenceMAWMTSTGCFDEVLTRGVSGDVYNLADCILQQAVVGSGANTLFLSYLKHSLCAHLISHAAVLKRIAKFEHLDRYHCMGELLDFLEQIIGGVTCRGKQEEGALTKAMLALVYWLMQIYEHALEVFSENNRALNSEQQLMVEKLGLVVEKLAQSQFLLGVVYVGKFEDPELYGLLVKKYELIDNLTAASGFVPPVVSQKNVTINDYLRKAALIDSDTLEMKEFDGRGIEPITYCLQPLIAIEILFNPNCDTQTYVAEFMSIQRLKGYTLSRLYCEIIRACLISLNNVNGTTRESFICAFTFIKVPHILRQIHMQSRLLNPTEYEETAKLDYSPEIVEAFELLLQDSPILDLMDARCACNTVECLLNEMLKNHLINEKQMKMIAARREQDTTGLQKLELNTNQHSIVKFVFRAEPPLVGILKTLGSDYNKVQEALLGMLLQVLSGNSFELILSVATVQGKLKTFISGLIKCNEASKQIPGEMGKVALARAALFDVSFLMLSFIVQSYGSEVVLAENGDSFFEKWVRECLVEKHKSKSPAVMVKLCDQNKVDELIVSLNSPEGLKGSSLKWHEICANIPGLLYQVLMAWENETLSTPEIKKFLDSLKSRFCCFSVCATSWLCAYMQVVRQDELLKPMNMVQQFLTAVSADELMQQENFKERLGLTVQIVRKMQQDFQRLPGTSPKLRTMLQSQNLVSQNPLEEQFEEVWKNVSERGWLPIDSTLVLENLLQSCGPFWLVDKLVQQIFHCKYIREMNKTMDIVFAIMHLDIERCTIALLSQLVPMMLLNKLQLSEIVDPFSRVLAKLCVYCIVATMEAPTGPLSKKRSRAAIDGDDLLADGLCPTPKMRKMGSDSCDSSSSDFMLEHAAAAAAAVAFATKEAASGGVSLREPLQGCLQTLFRTFAQYIVSDELSPKIYFMFQFLSLLVEVGRERVKPVLKLIPNGLVQSMLKINATDDMTVGFILRLYDLNATTGRTFAMSDLCLFRNIQMRKDSIKL
Length993
PositionTail
OrganismCulex quinquefasciatus (Southern house mosquito) (Culex pungens)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Culicinae> Culicini> Culex> Culex.
Aromaticity0.08
Grand average of hydropathy0.091
Instability index41.97
Isoelectric point5.78
Molecular weight111761.37
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24910
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.99|      16|      39|     416|     431|       1
---------------------------------------------------------------------------
  416-  431 (28.12/19.23)	GILKTLGSDYNKVQEA
  456-  471 (28.87/19.93)	GKLKTFISGLIKCNEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.60|      37|      43|     227|     269|       2
---------------------------------------------------------------------------
  227-  269 (63.32/66.83)	EPITYCLQPliaieiLFNPNCDT.QTYVAEFMSIQR...LKGYTL.SR
  273-  314 (50.28/39.24)	EIIRACLIS......LNNVNGTTrESFICAFTFIKVphiLRQIHMqSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     136.32|      37|      41|     648|     688|       3
---------------------------------------------------------------------------
  622-  645 (25.87/13.83)	...............QVVR..QDELLKPM.NMVQQFLTAVSA
  648-  688 (56.08/55.31)	LMQQENFKERLgltvQIVRKMQQDFQRLP.GTSPKLRTMLQS
  691-  728 (54.38/42.00)	LVSQNPLEEQF....EEVWKNVSERGWLPiDSTLVLENLLQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.34|      22|      33|     137|     158|       4
---------------------------------------------------------------------------
  137-  158 (35.28/22.51)	LMVEKLGLVVEKLAQSQFLLGV
  172-  193 (37.06/24.00)	LLVKKYELIDNLTAASGFVPPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.65|      33|      47|     889|     927|       6
---------------------------------------------------------------------------
  889-  927 (46.34/42.55)	QGCLQTLFRTFAqyivSDELSpkIYFMFQFLSLLVEVGR
  939-  971 (55.31/33.01)	NGLVQSMLKINA....TDDMT..VGFILRLYDLNATTGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.58|      32|     375|      96|     127|       7
---------------------------------------------------------------------------
   96-  127 (57.31/48.33)	KQEEG.....ALTKAMLALVYWLMQ...IYEHALE.VFSEN
  473-  513 (39.27/30.24)	KQIPGemgkvALARAALFDVSFLMLsfiVQSYGSEvVLAEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     173.56|      49|     473|     325|     378|       8
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  325-  378 (70.60/49.99)	AKL.DYSpeIVEAFEllLQDSPILDLMDARCACNTVeCLLNEMLKNHLINEKQMK
  761-  789 (34.98/13.79)	......................IMHLDIERC...TI.ALLSQLVPMMLLNKLQLS
  800-  844 (67.98/34.62)	AKLcVYC..IVATME..APTGP.LSKKRSRAAIDG.....DDLLADGLCPTPKMR
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24910 with Med24 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA