<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24887
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MANADTIQVSSLPLPPAQYINLFTDENIRKNRAPKPPPPIQDSYTMFGNPFSNDDNIIRPLEAQGFKRLYPQHFDRRKELKKLNHSLLVNFLDLIDLLVHYPDSPRRAEKIEDLSLLFVHIHHLLNEFRPHQARETLRVMMELQKRQRIETTQRFQNHLEKVREMVKAAFASLPDLTEADLSSATEPMDTGDESETGKGRGEGCHPLDRLMCELVDNM |
Length | 218 |
Position | Middle |
Organism | Culex quinquefasciatus (Southern house mosquito) (Culex pungens) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota>
Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae>
Culicinae> Culicini> Culex> Culex.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.645 |
Instability index | 47.78 |
Isoelectric point | 5.99 |
Molecular weight | 25236.49 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP24887
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 55.42| 15| 25| 13| 27| 1
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13- 27 (29.41/16.90) PLPPAQ.....YINLFTDEN
36- 55 (26.02/14.24) PPPPIQdsytmFGNPFSNDD
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 53.72| 16| 24| 91| 108| 2
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91- 108 (23.16/20.29) FLDLIDLLVHYpdSPRRA
118- 133 (30.56/18.59) FVHIHHLLNEF..RPHQA
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