<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24877

Description Thyroid hormone receptor-associated protein 6
SequenceMSGQYPSGYQSPSGHRGNFNSPMMQQQLGGGAGGGVPSQMGFNQGMQQNQQMQGGGQSGGGGELGMNPNQMAGGQQPTGGNQAGGQQQQQAAGQGAAQQSQAPQQSPQSGQQGQGGGNMMAPAGAPGPVATTGQPNMQQQKEFNLLTLCRIGQETVQDIVSRFQEVFGILRVIQPPNGTNQGLTASNDKKAKVQEQFRTIRLLFKRLRLLYDKCNDFCQQGMEYTHVEGLIPVKGEPERTEPVHTEEYKKAMQENRELIEIVMLKNKQLREIIDKIRLTIWEINTMLSMRRC
Length292
PositionHead
OrganismCulex quinquefasciatus (Southern house mosquito) (Culex pungens)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Culicinae> Culicini> Culex> Culex.
Aromaticity0.05
Grand average of hydropathy-0.784
Instability index59.57
Isoelectric point8.90
Molecular weight31792.48
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24877
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     126.39|      19|      22|      17|      35|       1
---------------------------------------------------------------------------
   17-   35 (38.37/11.28)	GNFNSPMMQ.QQL.GGGAGGG
   41-   60 (28.10/ 6.38)	G.FNQGMQQnQQMqGGGQSGG
   62-   78 (28.71/ 6.66)	GELG..MNP.NQM.AGGQQPT
   79-   97 (31.20/ 7.86)	GGNQAGGQQ.QQQ.AAGQGAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     215.81|      57|      59|     157|     213|       3
---------------------------------------------------------------------------
  122-  155 (42.03/16.56)	......................PAGAPGPVATTGQPNMQQQKEFNLLTL.......CRIGQET
  157-  213 (92.42/43.40)	QDIVSR...FQEVFGILRVIQPPNGTNQGLTASNDKKAKVQEQFRTIRLLF...KRLRLLYDK
  215-  275 (81.35/37.50)	NDFCQQgmeYTHVEGLIPVKGEPERTEPVHT.EEYKKA.MQENRELIEIVMlknKQLREIIDK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24877 with Med30 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MSGQYPSGYQSPSGHRGNFNSPMMQQQLGGGAGGGVPSQMGFNQGMQQNQQMQGGGQSGGGGELGMNPNQMAGGQQPTGGNQAGGQQQQQAAGQGAAQQSQAPQQSPQSGQQGQGGGNMMAPAGAPGPVATTGQPNMQQQKEFN
1
144










Molecular Recognition Features






MoRF SequenceStartStop




NANANA