<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24862

Description Cell division protein kinase 8
SequenceMSFAVMMDYEFKMKTQQERAKVEELFEYEGCKVGRGTYGHVYKAHRKESNDTKDYALKQIEGTGLSMSACREIALLRELKHTNVINLIRVFLSHTDRKVWLLFDYAEHDLWHIIKFHRAAKATKKPVMVPKGMVKSLLYQILDGIHYLHSNWVLHRDLKPANILVMGEGNERGRVKIADMGFARLFNAPLKPLADLDPVVVTFWYRAPELLLGARHYTKAIDIWAIGCIFAELLTSEPIFHCRQEDIKTSNPYHHDQLDRIFNVMGFPQDKDWEDIRKMPEHHTLTKDFKRSNYANCSLIKYMERHKIKPDSKAFHLLQKLLLMDPNKRITSEQAMQDPYFSEDPMPTGDVFAGCPIPYPKREFLTDEDQDQDKGESKRQQQQQQQQQQQQQQQQQANVTQQNQQQQQANHQNQQQQHQQQQQQQQQNQQGGMDHNAAKRARMAGPGGQPGDYQQQQQQQQQQAQQQQQQQQQQQQQQQMMFNNPQQGGFQQRY
Length494
PositionKinase
OrganismCulex quinquefasciatus (Southern house mosquito) (Culex pungens)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Culicinae> Culicini> Culex> Culex.
Aromaticity0.09
Grand average of hydropathy-0.980
Instability index58.84
Isoelectric point8.65
Molecular weight57998.83
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process
cell division	GO:0051301	IEA:UniProtKB-KW









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24862
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      93.45|      14|      33|     378|     391|       1
---------------------------------------------------------------------------
  378-  391 (31.36/10.01)	KRQQQQQQQQQQQQ
  412-  425 (30.24/ 9.40)	QNQQQQHQQQQQQQ
  466-  479 (31.85/10.27)	QQQQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.90|      14|      34|     443|     456|       3
---------------------------------------------------------------------------
  443-  456 (28.40/13.40)	MAGPGGQPGDYQQQ
  480-  493 (28.49/13.47)	MMFNNPQQGGFQQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.33|      13|      35|     326|     338|       5
---------------------------------------------------------------------------
  326-  338 (23.33/14.08)	PNKR.ITSEQAMQD
  360-  373 (18.99/10.13)	PKREfLTDEDQDQD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24862 with CDK8 domain of Kingdom Metazoa
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