<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24860

Description CRSP complex subunit 3
SequenceMSSDAQIAKLVEEIVGEKSNEEALVEAFGGMSAEVKEATLRQYLIRVAEINHRNKVHKHLQVLNKLVGLNLLPPRLLCEQIMSSEKLVFQNQSFWVECFQVVRKNIGGVDYKGVREIMKCCKEKALSFPSAIGSNILPQMQELTEVIEHIFNRNACLLPAYFIINEIQKADYQDTHWRIANLIANFIEEFVIVAQMLSIIGNSEKLPIVEHSSYADNLINPWKLDPNTLKLALRGNLPYEPELLQPQKKLLRFVLEQPYSRDMVCSMLNLQKQQKQKCIALEEQLVWLVICAMECSEKEPAHPADGEDMISSHTQWVWLHLSSQLIYFVLFQFATFQNIVNSLHDKLAVRNLRRGRDQLMWVLLQYISGSIQRNSITNFLPILKLYDILYPEKDPLPVPDYNNPFCTHQMAPTCIWIHLLKRAQSEHYNINRPIPTALKLHHEFLQHLVMPNNNATLCMGSDYRIALLCNAYSTNQDYFSRPMAALIETILGNSKNQSGAGGSQQLPTVPLSMCVLDSLTIHSKMSLIHSIVTHMIKQAQNKSTIPNANNMAPALVETYSRLLVYTEIESLGIKGFLSQLLPQVFKSHAWGILYTLLEMFSYRMHHIQPHYRVQLLSHLHSLASVPHTNQMQLHSCVESTALRLITGLGSVEVQAQLSRYVNEPKAPGNIVSAESEELNRALILTLARSMQITGTGNDPQSTWCKDLLTSIMTNTPHTWSQHTLQCFPPVLNDFFVQNSIPKENKQLLKKSVDEEYRNWAGMSNENDIISHFGAAGTPPLFLCLLFKMIVETDTISPVAYKTLERIGARALSAHLRKLCDYLVFEVSNSGVGAHVNKCVDTINDMIWKYNILTIDRLVLCLSLRTLEGNEAQVSFCIIQLLLLKTSEFRNRLQEFVNNNSPEHWKQNNWHERHLAFHQKFPEKFAPDESVSHPSTLPVYFGNVCLRFLPVLDITIHRYLEVPATMSKTLDVLLDHLGSLYKFHDRPITYLYNTLHYYEKRLRERPHLKRRLVGTVIGSLKDVRPENWALTKQYHEYMLKKDETVNWLPELNYYITLVRRMQDTIDGNNVFQGTDWRFNEFPNPPAHALYVSCVELLGLPVGPQTVANSLIDVVVKGYPVIPEFRVHNWINTIGLLMAALPESYWSVIYDRLKDIISSVQMTDWTHRQSPFEMFNFKIVKEAMLEKNYVVILAIAQSILHHSGIGQISTITDFIKEKFKPIIKTEYQLIYLCHVVGPFLNRLSTERPRAVSDITLILYELLEQVDKAQSSAPLKYMDPICDLLYHIKYMFVGDMMKSDLEAIIRRLRPALQMRLRFITRLNVDEIGVEQQATEGSIPAGGQSQAEFKPQVGQTVGAGGVGGTTVQQTQQSQPQAVQ
Length1375
PositionTail
OrganismCulex quinquefasciatus (Southern house mosquito) (Culex pungens)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Arthropoda> Hexapoda> Insecta> Pterygota> Neoptera> Endopterygota> Diptera> Nematocera> Culicoidea> Culicidae> Culicinae> Culicini> Culex> Culex.
Aromaticity0.09
Grand average of hydropathy-0.130
Instability index46.67
Isoelectric point7.07
Molecular weight157222.12
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24860
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     220.60|      66|      90|    1012|    1081|       1
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 1012- 1081 (112.82/95.54)	VG..TVIGSLKDVRPENWALTKQY..HEYMLKKDETVNWLPElNYYITLVRRMQDTIDGnnvFQGTDWRFNEFP
 1100- 1169 (107.78/77.79)	VGpqTVANSLIDVVVKGYPVIPEFrvHNWINTIGLLMAALPE.SYWSVIYDRLKDIISS...VQMTDWTHRQSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     318.60|      89|     289|     137|     233|       2
---------------------------------------------------------------------------
  137-  229 (144.71/126.67)	LPQMQEL.TEVIEHIF..NRNA..CLLPAYFIinEIQKADYQDTHWRIANLIANFIEEF...VIVAQM..LSIIG.N.........SEKLPIV.............EHSSYADNLINPwkLDPNTL
  434-  521 (105.11/76.45)	IPTALKLhHEFLQHLVmpNNNAtlCMGSDYRI..ALLCNAYSTNQDYFSRPMAALIE..............TILG.NsknqsgaggSQQLPTV.............PLSMCV........LDSLTI
  532-  609 (68.78/50.43)	VTHM...............................IKQAQNKSTIPNANNMAPALVETYsrlLVYTEIesLGIKGfL.........SQLLPQVfkshawgilytllEMFSYRMHHIQP........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     119.77|      39|     366|     813|     860|       3
---------------------------------------------------------------------------
   40-   78 (67.82/40.70)	LRQYLI.RVAEINHRNKVHKHLQVLNKLV.GLNLLP.PRL.LC
  818-  860 (51.94/49.36)	LCDYLVfEVSNSGVGAHVNKCVDTINDMIwKYNILTiDRLvLC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.86|      40|     238|     621|     667|       4
---------------------------------------------------------------------------
  621-  667 (51.92/58.41)	SLASVpHTNQMQLHSCVESTALrlitgLGSVEVQAQLSRYVNEpKAP
  862-  901 (66.94/46.93)	SLRTL.EGNEAQVSFCIIQLLL.....LKTSEFRNRLQEFVNN.NSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     182.23|      60|     292|     922|     990|       5
---------------------------------------------------------------------------
  922-  990 (88.37/81.62)	EKFAPdeSVSHPSTLpVYFGNVCLRFLPVLDitihryLEVPATMSKTLDVLLDHLGSLYKFHDR.PITYL
 1215- 1275 (93.86/60.91)	EKFKP..IIKTEYQL.IYLCHVVGPFLNRLS......TERPRAVSDITLILYELLEQVDKAQSSaPLKYM
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24860 with Med23 domain of Kingdom Metazoa
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