<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24851

Description Predicted protein
SequenceMRERKDDKQSSTSLPVYESDPPFWLPKMHSAADIGYAGFHPPRPGQDEDVLSETNVKNGFILTQPVSVETFSAQTMINENLKSEDSLAKLEELMNEVFIKRADHIPSVPPSSFRMPTRVTLNDAKRQAWFADLANPDVPLYKLGKSVPHGAKGHDLLDLLHANNVAISRAVWLLRVFGANETAGLRNKPSYNPTLYSVEWANVVTSYIKKQLLEIALPSAPRPGLNIKQTFKGVLSDLDSREKWISRFMYCLKLLRTFYAEGLVDHQTFLVWIVQQMGCCNLAQAGFLTRLTEEYLDDILGSRALARPLVEACLGKMSEIGTASAQEFLSGTEESLKHLLQRSCLILPDAFIGPRMWLAYPSIIERVMTVDSSNHLNDWFLSQNIQDIRQSIFANFLDVRKRNEALLFCNPPPHMSIRLQAAVSDVKLLNSISSDTEMSSVTFFGNDFNDSPFFQEKLDMLLSWCVTPLQYGNHRPFAAVTLIKNWRDKACERATRRDFITPNELLQDQLFDWLDKSDVAGEPNNIRDVALLYGKLVKHELFSYASYIQRLIARGEPGLSFAEDIESRHRRFLSWIPLFQSTSSLINQRKVTLHGVRARNIPEDMTEREIRKEIRSVLPEVFGGVIRSTLETTADLLANCNALMTGTRFEQVRTFRQWLLPALQKHIASNNDRPSALRAYLVTVELMTSTKCFHSVLDLTFCMLEHSTDSDSMTAVLDTFHRHAVIWACMGAMNAIVSALDTAHQVWKLRGTQSRPLLALLIEFDNGRYLDELSRTRITAEMSTFTNALQPVVGRPNHVPDILPEILLLAGDPDDNAPAILANGLWIKYRMSLDWAWKTWDNTVASLRQVPSMTSDVNSRRLHALRYGTFLWRVDQHLPNGLDMDVLRWFNGPGKGVLVALSPDSWDMLMTILVYLIVHGALETTTILSGLVYPAWELGAFSSMEQAAFPETYLRAANDLCHRLLLQENDSGDAIPPTNLFEVQCLRTRRQVVYYEPHFPCLVTSIPVLISLENNPNISGDLRRDSTSLRQRLCQDGGFRQGAYRSMDVVREAFENSPYFKDMGSEILGKQMIAGLRMILCDSTDDTNLYDWPEVTRLLSPWKVAATTIQMQFQIKQLGRSLAQDITHDNASANLDKLTVMLFNHTNTAEEAYYVGEMARGAGSAVVAKFIKNGLKCIAENLSATSCDEAPGIECPGSVAELLRVLTHVSSPFRDGLSSLPSLDPSTQTLFFEVIHAKLTTLQPQCISKEKLYLQRDNIILLARLLQFILNFRGSWSSRAKELGSDLTTMVFHVALHHATGDNLDAVVYSILIDTLLFLYDGAHLLSLFHLQNLKNDFVLPEIPSDGKVGAFDPYRLYPDIPVTDLPSDLPPVYRKQCLSLLCRTTTISTVPDLVNSHRDTQGNLVLGPYVVNRPWEWIENLEPSVLDRKEGEKERDDKDSQKTKYPVKNSGSLSLDAFGARLTGDSIVPIVADGCNLRTEGNIRSFQDGTSSDSLFIRDWRETRLDLKLEIPTSLRSRPKSDFPVGTGPIHTASLRPDPRTTPKASPASSIVSRSSAHDFSSSARQQSPGQGSHGHSNTGMGEASGDVAGASAMTLRKEPTSKRKATALVSDEVEIIEGPVPVRAGTNSKKAKVTKAPVAKAKAKRK
Length1648
PositionKinase
OrganismLaccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured deceiver) (Laccaria laccata var. bicolor)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Tricholomataceae> Laccaria.
Aromaticity0.08
Grand average of hydropathy-0.224
Instability index47.56
Isoelectric point6.41
Molecular weight184477.52
Publications
PubMed=18322534

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24851
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.89|      35|      59|    1202|    1237|       1
---------------------------------------------------------------------------
 1202- 1237 (56.23/43.57)	LLRVLTHVSSpFRDGLSSLP.SLDPSTQTLFFEVI..HA
 1262- 1299 (52.66/34.79)	LARLLQFILN.FRGSWSSRAkELGSDLTTMVFHVAlhHA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     326.79|      92|     176|      42|     157|       2
---------------------------------------------------------------------------
   42-  145 (140.45/134.67)	PRPGqdedvlseTNVKNGF..ILTQPVSVETFSAQTMIN.ENLKS..EDSLAKLEE....LMNEVFIKRADHI..PSVPPSSFRMPTRVT...LND..AKRQaWFadLANPDVPlYKLGK
  221-  316 (123.90/86.42)	PRPG........LNIKQTFkgVLSDLDSREKWISRFMYClKLLRTfyAEGLVDHQT....FL..VWIVQQMGC..CNLAQAGFL..TRLTeeyLDDilGSRA.....LARPLVE.ACLGK
  319-  380 (62.44/34.65)	...........................EIGTASAQEFLS.G...T..EESLKHLLQrsclILPDAFIGPRMWLayPSIIERVMTVDSSNH...LND.......WF...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      33.86|      10|      46|     643|     652|       3
---------------------------------------------------------------------------
  643-  652 (19.22/12.79)	LMTGTR.FEQV
  686-  696 (14.65/ 7.84)	LMTSTKcFHSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.78|      22|      46|     821|     842|       5
---------------------------------------------------------------------------
  821-  842 (45.35/28.24)	LANG..LW.IKYRM..SLDWAWKTWDN
  865-  891 (29.43/15.70)	LRYGtfLWrVDQHLpnGLDMDVLRWFN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24851 with Med12 domain of Kingdom Fungi
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