<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24833

Description Predicted protein
SequenceMGRHTLLVLGLLFAAGVAGSFGAAEEAAKLGTVIGIDLGTTYSCVGVYKNGHVEIIANDQGNRITPSWVAFTDNERLIGEAAKNQAAVNPERTVFDVKRLIGRKFEDKEVQKDIKLFPYKIVNKDGKPHIQVKVKDGEVKVFTPEEISAMVLVKMKETAEAYLGKKIKDAVVTVPAYFNDAQRQATKDAGVIAGLNVARIINEPTAAAIAYGLDKKGGEKNILVFDLGGGTFDVSVLTIDNGVFEVLSTNGDTHLGGEDFDQRIMEYFIKLIKKKHNRDISKDKKAIGKLRREAERAKRALSNQHQIRVEIESLFDGVDFSEPLTRARFEELNNDLFRKTMGPVKKAMDDAGLQKTDIHEIVLVGGSTRIPKVQQLLRDYFDGKEPNKGVNPDEAVAYGAAVQGGILSGEGGEETKDILLLDVAPLTLGIETVGGVMTKLIPRNTVIPTKKSQVFTTYQDQQTTVSIQVFEGERSLTKDCHELGKFDLTGIPAAPRGVPQIEVTFEIDANGILNVKAEDKGTGKSEKIVITNDKGRLSQEEIDRMVQEAEEFAEEDKKVKERIDARNSLETYVYNMKNQLGDKLGEKISAEDKETIETAMKEALEWLDENQSAEKEDFQEKLKEVEGICNPIVTKLYQAAGGAPGAGASEDGESDDESHEEL
Length662
PositionUnknown
OrganismPhyscomitrella patens subsp. patens (Moss)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Bryophyta> Bryophytina> Bryopsida> Funariidae> Funariales> Funariaceae> Physcomitrium.
Aromaticity0.06
Grand average of hydropathy-0.420
Instability index27.85
Isoelectric point5.12
Molecular weight72657.44
Publications
PubMed=18079367
PubMed=29237241

Function

Annotated function 
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
endoplasmic reticulum chaperone complex	GO:0034663	IBA:GO_Central
endoplasmic reticulum lumen	GO:0005788	IBA:GO_Central
membrane	GO:0016020	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central

GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
endoplasmic reticulum unfolded protein response	GO:0030968	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central
ubiquitin-dependent ERAD pathway	GO:0030433	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24833
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.83|      21|      21|     582|     602|       1
---------------------------------------------------------------------------
  558-  578 (23.42/15.16)	.KVKERIDARNSlETYVYNMKN
  582-  602 (34.46/26.40)	DKLGEKISAEDK.ETIETAMKE
  605-  624 (32.95/24.87)	EWLDENQSAE.K.EDFQEKLKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.56|      17|      21|      62|      79|       2
---------------------------------------------------------------------------
   62-   79 (28.32/23.21)	NR..ITPSWVAFtDNERLIG
   84-  102 (26.24/16.11)	NQaaVNPERTVF.DVKRLIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     440.25|     166|     195|     117|     311|       3
---------------------------------------------------------------------------
  117-  173 (26.23/19.73)	............................................................................................................................................................FpykivnkD...............G....KPHIQVKVKD.GEVKVFTPEEISAMVLVKMKETAEAYLGK.KIKDAVVT
  174-  364 (211.07/211.11)	VPAYFNDaqRQATKdaGViaglnvariiNePTaAAIAYG.......LDKKGGE..KNILVFDLGGGTFDVSvlTIDNGVFEVLSTNG.....DTHLGGEDFDQRiMEYFIKLIKkkHNRDISKDKKAIGKLRREA.ERAKRALSnQHQIRVEIeslF.......D...............GvdfsEPLTRARFEE.LNNDLFR....KTMGPVK.KAMDDAGLQKtDIHEIVLV
  377-  554 (202.95/143.83)	LRDYFDG..KEPNK..GV..........N.PD.EAVAYGaavqggiLSGEGGEetKDILLLDVAPLTLGIE..TVGGVMTKLIPRNTviptkKSQVFTTYQDQQ.TTVSIQVFE..GERSLTKDCHELGKFDLTGiPAAPRGVP.QIEVTFEI............dangilnvkaedkgtG....KSEKIVITNDkGR...LSQEEIDRMVQ.EAEEFAE..............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.27|      20|     623|       7|      26|       4
---------------------------------------------------------------------------
    7-   26 (33.71/19.25)	LVLGLLFAAGVAGSFGAAEE
  632-  651 (35.55/20.67)	IVTKLYQAAGGAPGAGASED
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24833 with Med37 domain of Kingdom Viridiplantae
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