Description | Predicted protein |
Sequence | MDIIAQLQEHASAIAYIAFNAAGTIQRDAPPSQLAQDYPKPTGITTEALEQPKEMATAFVQAVQRFDALVSALPDIQGGEEAQLKRIAELEAENEAFGQELQRELEAADSELNQIQELFDMATDNWLQMKPP |
Length | 132 |
Position | Middle |
Organism | Physcomitrella patens subsp. patens (Moss) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Bryophyta> Bryophytina> Bryopsida> Funariidae> Funariales> Funariaceae> Physcomitrium. |
Aromaticity | 0.06 |
Grand average of hydropathy | -0.376 |
Instability index | 43.27 |
Isoelectric point | 4.13 |
Molecular weight | 14556.08 |
Publications | PubMed=18079367 PubMed=29237241 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU366036 |
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central |
GO - Biological Function | transcription coregulator activity GO:0003712 IBA:GO_Central |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central |
Binary Interactions |
Repeats | >MDP24825 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 3| 122.37| 35| 37| 43| 77| 1 --------------------------------------------------------------------------- 18- 57 (46.22/25.52) AFNAAgtIQR..DAppsqLAQDYPKPTGITTEALEQPKEMAT 58- 92 (57.71/33.33) AFVQA..VQR.FDA....LVSALPDIQGGEEAQLKRIAELEA 96- 116 (18.44/ 6.64) AFGQE..LQReLEA....ADSELNQIQ............... --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EEAQLKRIAELEAENEAFGQELQRELEA 2) SQLAQDYPKPTGITTEALEQ 3) TAFVQAVQ | 80 32 57 | 107 51 64 |
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