<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24813

Description Protein CBR-MDT-17
SequenceMESGSASPSSPEPIVIDEGPEKPPSILAPRKGVDLVLEANDDWKIQEIGFDGVEKYLKPETFTDQVGKLARRVEWMKLVGSSTPYENAKIDQTEELDDEGVPSRKGEKGGTNVELVTPEAGPWSSVAKYLHESLSQLNVLLDDLSVMKNTDYMKALTVLDPITIAEPTPEHIQTMRGTQWIWKRRALQEAVQVLDIAQKQRQQALRNLGLSVDYIAHLQRTKFFEELKEMREIWRVRKTGDYVYGDLSYHIFGWKYDTPNLFDISRRSLSNKFETSDLSIIEVSVPKDLARRSMLVVKIVKDDIESGDLFRDPKSNDYAYSYKEVDAEKVKALHWKDSLKWAQNTLLLRDTFNTLCKDAIKLRNRLSIIRDNVLLIRLFDDYLLRFELQWFPFEAGQIHEEGDIYLNRVLREMIIGFECTKFVRPQFFCSMPITHLPESLDLRGCGGFDARQIADRAVTPRSILDRMLDMAAHRALVNMMTEVAELMCGSSVDPTIQYKWLHCGRNYSKMMFQVVSKDYDLYLSGHRMHHTFFASVSSDGITIETKDGMLIKCDRDSARVLYACQYCVCIYQVSMFAMVCRNQWITPFQTLYSNVYALDDKGNPAPNILLCNQAATRSILFKFHVGRDPEILVRRFVVNEKTAKPEEHPWKKLSYRKLYGATFCKKVDALLSFLRDC
Length677
PositionHead
OrganismCaenorhabditis briggsae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.10
Grand average of hydropathy-0.335
Instability index42.03
Isoelectric point6.44
Molecular weight77975.74
Publications
PubMed=14624247

Function

Annotated function 
GO - Cellular Component
core mediator complex	GO:0070847	IBA:GO_Central
mediator complex	GO:0016592	IBA:GO_Central

GO - Biological Function
transcription coregulator activity	GO:0003712	IBA:GO_Central

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24813
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.39|      30|      70|      53|      88|       3
---------------------------------------------------------------------------
   53-   88 (39.28/48.68)	VEKYLKpETFTdQVGKLARRVEWMKlvgsSTPYENA
  126-  155 (51.11/36.54)	VAKYLH.ESLS.QLNVLLDDLSVMK....NTDYMKA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.67|      15|     314|     341|     371|       4
---------------------------------------------------------------------------
  354-  371 (22.06/38.23)	TLCKdaiKLRNRLSIIRD
  662-  676 (27.61/ 7.76)	TFCK...KVDALLSFLRD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.05|      16|      16|     246|     261|       7
---------------------------------------------------------------------------
  246-  261 (31.60/20.94)	DLSYHIFGWKYDTPNL
  263-  278 (26.46/16.37)	DISRRSLSNKFETSDL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.19|      16|      16|     185|     200|       8
---------------------------------------------------------------------------
  185-  200 (25.40/15.77)	RALQE.AVQVLDIAQKQ
  203-  219 (22.79/13.51)	QALRNlGLSVDYIAHLQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24813 with Med17 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ENAKIDQTEELDDEGVPSRKGEKGGTNVELVT
2) MESGSASPSSPEPIVIDEGPEKPPSILAPRK
86
1
117
31










Molecular Recognition Features






MoRF SequenceStartStop




NANANA