<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24808

Description Mediator of RNA polymerase II transcription subunit 5
SequenceMALHLIQDVEAAGAELFTLLVSTTVRDSWPEIESDAPHLPSVLHAIHILLTRFNAVSSPSPRAKATLQSLNALKNGLTTPLNDDLFGEQQPAASVPSLWASRAFFSYAVSLQLVWRQVESSGGRRPVLPPPVFPEPETILLVHGLCAPNLNWYQKCLEALGILKTRLHYSNEPPNDICCAYLMEIFVAITHAAIVQLKRHPTERHAQVWRHVIGGLLPPLALFLGGSVPASNNDVLNVQDTVSSFIAFYEPVNDWMHLDAQIMAPSHAATLPDLMQDSFAAWLPGHSKKTTSIELENLHQYASTSVQSFRQIVHTSLLHNPSACGNLIERAVKEPCLQLVLAMELNHLLSEWTEFMSAEFMHMHAICYLLQSGAPQNLDMLCLYMGQQLLPHTLVHVLSHMDQSMWSHPDDALNLVILFVEYLSYYSKESGNPSKGAAYVFMRRRLSCFNSHALPEEYLTLLSRWCRCLVGSDDMSELLTASPPWLLFRLTPSIFKLLIEAFLYGFFDESTLLNAFAYFLRVPLRYNVPCAVNWLVRYTTMTLAKAQYDPKLWSLIFLLVRTLHMLFMSDACPPLIRSMLAGVVLPLLQNERLVLMTHTSNVNIPVFISTLQSYTDPHLPQSPWIVDVLMMCEDAKPWYSLVQRIGIITLQGLDTCIARQLLGVALQTRAEQVWTIKLLAAVFSLLHLNSKATKPLSLVRVILLQWDASSSKPEHIRNLGRILVLSVLLSKNLPASADALETVFGSLLTPSAEPLAHILRSET
Length763
PositionTail
OrganismMalassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Malasseziomycetes> Malasseziales> Malasseziaceae> Malassezia.
Aromaticity0.09
Grand average of hydropathy0.219
Instability index58.76
Isoelectric point6.25
Molecular weight85455.51
Publications
PubMed=18000048

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24808
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.81|      21|      21|      29|      49|       1
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   29-   49 (38.07/25.85)	WPEIESDAPHLPSVLHAIHIL
   53-   73 (31.74/20.14)	FNAVSSPSPRAKATLQSLNAL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     179.73|      54|      87|     481|     553|       2
---------------------------------------------------------------------------
  481-  548 (85.41/66.29)	ASPPWLLFRLTPSIFKLLIEAFLYGFFDESTLlnafayflrvplryNVPCAVNWLVRYTTMTLAKAQY
  571-  624 (94.32/53.01)	ACPPLIRSMLAGVVLPLLQNERLVLMTHTSNV..............NIPVFISTLQSYTDPHLPQSPW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.64|      12|      91|     114|     130|       3
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  114-  130 (16.56/22.76)	VWRQVesSGGrrpVLPP
  208-  219 (27.08/15.26)	VWRHV..IGG...LLPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     167.39|      36|      87|     355|     390|       5
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  317-  349 (31.36/16.54)	................LLHNPSACgNLIERAVKEPCLQL.....VLAME...lNHLL
  355-  390 (62.69/41.32)	FMSAE...........FMHMHAIC.YLLQSGAPQNLDML.....CLYMG....QQLL
  393-  420 (36.50/20.61)	TLVHV...........LSHMDQS....MWSHPDDALNLV.....ILFV.........
  425-  479 (36.85/20.88)	YYSKEsgnpskgaayvFMRRRLSC.FNSHALPEEYLTLLsrwcrCL.VGsddmSELL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.87|      11|      15|     685|     695|       6
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  685-  695 (18.74/ 9.31)	LLHLNSKATKP
  703-  713 (20.13/10.48)	LLQWDASSSKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.63|      29|     575|      75|     106|       8
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   75-  106 (48.50/35.51)	NGLTTPLNDDLFGE..QQPAASVpslWASR...AFFS
  651-  684 (42.13/23.20)	QGLDTCIARQLLGValQTRAEQV...WTIKllaAVFS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24808 with Med5 domain of Kingdom Fungi
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