<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24802

Description Uncharacterized protein
SequenceMKEATKARAPNEVTAVETSDIDVPRWRPLLHHNEPQLGYAGVRLPSHNPVVPTRHLRFGASCKPPVPEDTGSVHDKIYEQLSKYGAVDFLSSMLDTLRQHRRSRNHIADDKSVQWKPLAQPAVSETMLDMYSRDLANRDVPFATVARRLPRRISAEKILDLLWRAPMGSSPYSVPLPRAIWLIRHECSLDIQEAQERGDNADQCIYEWNHSVLQWLQQSLDSLPTSEDQRHVWAHRWDYATALVHSLMHAQLLEPYIFYRWIVTQLDVVRGAPRACVAQLAMIHMEDILTHAALGTALVTALARVAESSFPWLRQQSHAMLFHCARLQPHALAHARSFLNDSRVLSQYLTQERVCKKAELLPTALFPLLPHYEAWDVAAVRALDSQTSVSSTFIAFFLPREATTEAFVKQRLHILYEWSCVHKHCGSHSGMHRAFIATALVRLLDECQSQRLASSDGRMIPCPWKPISIPEVTLQWTDKLVSASELNLVAAARLLGSLAEINMFSYMQFLQRLSTRGLVRSGTEPRLHHHRLDSHDLMRLLRSIPTHRLTAAQQQQRRLAIYGPRPSESYEETVERRAIRELHHVFHWHSDVPNVARSPTQDPPRSTVTSPDAYSANSLCASPTPYLSRSTVASPNPYVPRISVISPTLEANELVSPKPASPATPSDPTADILEAFQLRTRLPHLWNASPYVQARIVNRFLSPMLFHDLSALNADRFALTASVLTKIHAMQTLGRLMCALLDGHNLSCVISICHTVVMYARIWDALEIAPDLVGRIVPYAITEPVINSEIERVISVAGRGMTVAMARRALHALGELDVSVPNYAPMPQAPLVKEPDACAEQLFVSLCHTQPTQACVPIAQHATLDETAAHLLVYALDKLAQSPTYPPAALSTLLATLAGTVGVRLDENVHAWIHRTWRQPSAHATSSMWIVLVVGLVRHGFVHAPELLQRVIAPFMEQAPATHPGWDACMSLLFSLVFTYTAEQHPCSIDILGEAGWYDVNLLRADIAYTDGFVPLLSALDLCETPHRWQCWNVLSHQVPKLHALWMARPDAIWRGTLTLRGKDRFQRVRRLIHVLMEQEPRGTLPQPRAATMTSSLHAPSLNVNDLYEGSLAALQWRLVLEEAKAITAEVGRMLLAPRSSQAPIDLVLQWDASPHIVSILAQYALHTFVQAIDTPHHLPNAISGLAHLMYAYRCASPIKCDASLATQSVQCLTRLPTSLAPVLRASAILSVLRCAARVHSDAWLVVLANLCDEARDSPLASTVAAHVQCWIDPTVLDTWLRSRVSTNEGEVENTDAGSVSSLLRYSRDITRLRTCLPADLVSSPWDWHDQVSETPADAVPADPWSHYLHNGTSVPLSLFHAQKTRDRVPICADGPPTRLVSETSYGDGDDAVTRYKPMTNVPVPERGLKAKAKRSSSRGGSGGSINHTTPTPEQAAHPSYVASANPDAGGRPSPAANSDKDQPAKRARIKI
Length1472
PositionKinase
OrganismMalassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Ustilaginomycotina> Malasseziomycetes> Malasseziales> Malasseziaceae> Malassezia.
Aromaticity0.07
Grand average of hydropathy-0.147
Instability index53.82
Isoelectric point7.67
Molecular weight163735.54
Publications
PubMed=18000048

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24802
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.43|      36|      39|    1166|    1203|       1
---------------------------------------------------------------------------
 1166- 1203 (61.82/47.56)	LHTfvQAIDTPHHLPNAISGL...AHLMYAYRCASPIKCDA
 1205- 1243 (54.61/34.82)	LAT..QSVQCLTRLPTSLAPVlraSAILSVLRCAARVHSDA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     358.64|     116|     129|      54|     182|       2
---------------------------------------------------------------------------
   34-  164 (172.78/122.75)	EPqLGYAGVRLPSHNPVVPtRHlrfgaSCKPPVPE..DTGSVHDK.IYEQlsKYGAVDFLSSMLDTLRQHRRSRnHIADDKSVQWKPLAQPAVSETMLD...MYSRDLANRDV....PFATVArrlprRISAEKILDLLWR
  165-  291 (185.86/103.33)	AP.MGSSPYSVPLPRAIWLiRH.....ECSLDIQEaqERGDNADQcIYEW..NHSVLQWLQQSLDSLPTSEDQR.HVWAHRWDYATALVHSLMHAQLLEpyiFYRWIVTQLDVvrgaPRACVA.....QLAMIHMEDILTH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     122.44|      30|      33|     593|     625|       4
---------------------------------------------------------------------------
  593-  623 (57.13/30.69)	PNVARSPtQDPPRSTVTSPDAYSAN....SLC.ASP
  640-  657 (22.97/ 6.61)	...........PRISVISP.TLEAN....EL..VSP
  821-  851 (42.34/16.97)	PNYAPMP.QAP.L..VKEPDAC.AEqlfvSLChTQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.56|      31|      35|     897|     929|       5
---------------------------------------------------------------------------
  897-  929 (54.73/37.54)	LagTVGVRLDENVHA..WIHRTWR..QPSAHATSSMW
  932-  966 (46.83/25.82)	L..VVGLVRHGFVHApeLLQRVIApfMEQAPATHPGW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.03|      26|      35|    1315|    1348|       9
---------------------------------------------------------------------------
 1315- 1342 (41.33/21.09)	TCLPADLVSSpWDWHDQVsETPADAVPA
 1353- 1378 (44.70/25.08)	TSVPLSLFHA.QKTRDRV.PICADGPPT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.48|      19|      35|    1082|    1100|      10
---------------------------------------------------------------------------
 1082- 1100 (34.54/22.69)	RGTLPQPRA..ATMTSSLHAP
 1118- 1138 (25.94/14.93)	RLVLEEAKAitAEVGRMLLAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.42|      24|      25|     407|     431|      11
---------------------------------------------------------------------------
  407-  431 (41.51/31.73)	FVKQRLHILYEwSCVHKHCGSHSG.M
  435-  459 (35.91/20.78)	FIATALVRLLD.ECQSQRLASSDGrM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     207.19|      64|     491|     515|     586|      15
---------------------------------------------------------------------------
  515-  586 (97.10/64.77)	TRGLV..RSGTEPRLHHHRLDSHDLmrLLRSIP.THRLTAAqqqqRRLAIYGPRPSESYEETVERraIRELHHVF
 1010- 1076 (110.08/55.16)	TDGFVplLSALDLCETPHRWQCWNV..LSHQVPkLHALWMA....RPDAIWRGTLTLRGKDRFQR..VRRLIHVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.51|      16|     930|     333|     354|      17
---------------------------------------------------------------------------
  333-  349 (23.32/ 9.47)	AHARSFLnDSRVLSQYL
 1266- 1281 (31.18/10.74)	AHVQCWI.DPTVLDTWL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24802 with Med12 domain of Kingdom Fungi
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