<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24785

Description Uncharacterized protein
SequenceMPCVVLSFEWSFVCSLRPYWTLFWNANGSSPCPVLLDVPPTRISTSLPTLLLLLPPPAKPTVSKSNPKYPYPQANGPLTEQNVFDYFATSMFYDKQSNNQVLRMQTIYTGVPIANEAEELRRFTGIEFAVVHAQPPAFFIIHKRERISPDEVKPLAAYFINNNRIYQAPDLYSLLSNRLLTSVSALQTTLDVLRKKRPDYTPRTGFVWPIVGEPEDDAKKKAGEKGGKGGGTGTAKKELVPSLNPTADKAGGGRLSDMAGGVGGPEGDDGGDGGVDGDPTEPATSQVPGGGGSGGGIGKEGTQGTQSAPTPGSTTQKRQNTILLMNAMRTTAVHSKIGLPAGIDTRLAAAESSATGVGGANEGAPASAGGGGDSGGATPATSALRSSATPAPSGQEAAIKGVNPNAEGTKKKKKKRLSIAPTPAAS
Length426
PositionHead
OrganismCoprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003) (Inky cap fungus) (Hormographiella aspergillata)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Psathyrellaceae> Coprinopsis.
Aromaticity0.06
Grand average of hydropathy-0.393
Instability index44.56
Isoelectric point9.13
Molecular weight44313.42
Publications
PubMed=20547848

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24785
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     241.67|      73|      78|     221|     295|       1
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  202-  258 (61.93/23.30)	...........................PRTGFVwPiVGEPEDDakkKAGEKGGKGG...GTGTAKKE....LVP.SLNPTADKAGGGRLSDM
  259-  343 (105.17/52.08)	AGGVGGP.EG...DDGGdGGVDGDPTePATSQV.P.GGGGSGGgigKEGTQGTQSAptpGSTTQKRQntilLMN.AMRTTAVHSKIGLPAGI
  354-  422 (74.56/30.14)	ATGVGGAnEGapaSAGG.GGDSGGAT.PATSAL.R.SSATPAPsgqEAAIKGVNPN...AEGTKKKK....KKRlSIAPT............
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.85|      16|      16|      31|      46|       2
---------------------------------------------------------------------------
   31-   46 (31.09/18.89)	PCPVLLDVPPTR..ISTS
   48-   65 (23.76/12.62)	PTLLLLLPPPAKptVSKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.07|      17|      17|     134|     150|       3
---------------------------------------------------------------------------
  134-  150 (32.99/25.02)	QP.PAFFIIHKRERISPD
  153-  170 (28.08/20.22)	KPlAAYFINNNRIYQAPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.13|      16|      22|      69|      84|       4
---------------------------------------------------------------------------
   69-   84 (30.06/20.85)	YPYPQANGPLTEQNVF
   93-  108 (28.06/18.99)	YDKQSNNQVLRMQTIY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24785 with Med6 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RTGFVWPIVGEPEDDAKKKAGEKGGKGGGTGTAKKELVPSLNPTADKAGGGRLSDMAGGVGGPEGDDGGDGGVDGDPTEPATSQVPGGGGSGGGIGKEGTQGTQSAPTPGSTTQKRQNTILLMNAMRTTAVHSKIGLPAGIDTRLAAAESSATGVGGANEGAPASAGGGGDSGGATPATSALRSSATPAPSGQEAAIKGVNPNAEGTKKKKKKRLSIAPTPAAS
203
426










Molecular Recognition Features






MoRF SequenceStartStop




1) PATSALRSSATPAPSGQEAAIKGVNPNAEGTKKKKKKRLSIAPTPAAS
379
426