<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24782

Description Heat shock protein 70A
SequenceMGKEAPAIGIDLGTTYSCVGVWQNDRVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPRHTVFDAKRLIGRKFSDPIVQADIKLWPFQVRAGAHDVPEIVVSYKNEEKVFKAEEISSMVLIKMKETAQAFLGADREVKKAVVTVPAYFNDSQRQATKDAGMIAGLEVLRIINEPTAAAIAYGLDKKDSGLGERNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFDERLVNHFANEFQRKYKKDLKTSPRALRRLRTACERAKRTLSSAAQTTIELDSLFEGVDFATSITRARFEELCMDLFRKCMDPVEKCLRDAKMDKMTVHDVVLVGGSTRIPKVQQLLQDFFNGKELNKSINPDEAVAYGAAVQAAILTGEGGEKVQDLLLLDVTPLSLGLETAGGVMTVLIPRNTTIPTKKEQVFSTYSDNQPGVLIQVYEGERARTKDNNLLGKFELTGIPPAPRGVPQINVIFDIDANGILNVSAEDKTTGNKNKITITNDKGRLSKDEIERMVQEAEKYKADDEQLKKKVEAKNSLENYAYNMRNTIREDKVASQLSASDKESMEKALTAAMDWLEANQMAEVEEFEHHLKELEGVCNPIITRLYQGGAGAGGMPGGAPGAGAAPSGGSGAGPKIEEVD
Length651
PositionUnknown
OrganismChlamydomonas reinhardtii (Chlamydomonas smithii)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Chlorophyta> core chlorophytes> Chlorophyceae> CS clade> Chlamydomonadales> Chlamydomonadaceae> Chlamydomonas.
Aromaticity0.06
Grand average of hydropathy-0.361
Instability index30.36
Isoelectric point5.25
Molecular weight71214.01
Publications
PubMed=17932292

Function

Annotated function
GO - Cellular Component
cytoplasm	GO:0005737	IBA:GO_Central
GO - Biological Function
ATP binding	GO:0005524	IBA:GO_Central
ATPase activity	GO:0016887	IBA:GO_Central
heat shock protein binding	GO:0031072	IBA:GO_Central
misfolded protein binding	GO:0051787	IBA:GO_Central
protein folding chaperone	GO:0044183	IBA:GO_Central
unfolded protein binding	GO:0051082	IBA:GO_Central
GO - Biological Process
cellular response to unfolded protein	GO:0034620	IBA:GO_Central
chaperone cofactor-dependent protein refolding	GO:0051085	IBA:GO_Central
protein refolding	GO:0042026	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP24782
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.37|      10|      25|     206|     215|       1
---------------------------------------------------------------------------
  206-  215 (19.03/ 9.27)	LGGGTFDVSL
  234-  243 (19.34/ 9.52)	LGGEDFDERL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.45|      18|      21|      36|      53|       2
---------------------------------------------------------------------------
   14-   31 (18.51/11.47)	....TTYSCVGVWQNDRveIIA
   36-   53 (32.70/26.40)	NR..TTPSYVAFTDTER..LIG
   58-   76 (25.23/18.53)	NQvaMNPRHTVF.DAKR..LIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.46|      20|      41|     337|     356|       3
---------------------------------------------------------------------------
  337-  356 (34.59/24.49)	VHDVVLVGGSTRIP.KVQQLL
  381-  398 (27.63/18.03)	VQAAILTGEGG..E.KVQDLL
  418-  434 (16.24/ 7.46)	....VLIPRNTTIPtKKEQVF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.60|      31|     293|     148|     180|       4
---------------------------------------------------------------------------
  148-  180 (47.32/33.31)	VTVPAYfnDSQRQATKDAGMIAGLEVLRIINEP
  444-  474 (53.28/31.10)	VLIQVY..EGERARTKDNNLLGKFELTGIPPAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.02|      14|      38|     258|     273|       5
---------------------------------------------------------------------------
  258-  273 (21.21/22.00)	DLKTS.PRAlrRLRTAC
  298-  312 (21.82/14.41)	DFATSiTRA..RFEELC
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP24782 with Med37 domain of Kingdom Viridiplantae

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