<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24755

Description Uncharacterized protein
SequenceMSPTKYVLVPPDELHPYINKKDENSNDGNNANNKEMTYPDFDPWRHTKSEDDIMINFVSKGYYTTPKVNFESISARSSLQESLPKLSNHLAEQFSQVLQIREKEINKIPYGNNDPSSSSTQHQLFSLLSGPGFQLPNRVTLTDQRKDQWLQELSSPYASLTKISKFIPHGLKRRQVLEQCCMRQIPLKRAIWLLKCCYSMEWKALSTKHLNSKEINSQLLKEWTENFIFMLEKLVFEMSQYYNDAAKLKVWKREIYYFLKLLGNCYTLELINKDILLHWLVEFISKIEIFEYLPLSLHILSLFWHDISNVNESAPSAQPMFLVTKISDTLLHKYIAVSHNKSMINDEKYIINDVKKNNKIKESILAVIRRLICDLFQRQLLEVFLFPTSSWDLYKPCLYEITNQLNDTPEMVAEVKKKLELISYRNESLKLHYTSRSHTPEDESGTNTSNDESKIEFIKLNCIDFELTEKLDDNPIDFDWASFVDREIQNVSQIVQLILWVIHPSRACRYEGTQLVAKILLLTISSVEGLQEYVVEDIIWSVVFQISKYSEQKRSTFVSLPSLYKLLNMLITYGIVKVPTYIRKLISSGVLYLPESNDKFFHCDALINLKISFLMKSQYNMVLRNVIEYDATFYEKYNFDQLLSVTDELKQKILDSEELDMSEQPYSIKIMMAEWYLGLICGGELEVVNKQTLMKNFNFFCIHFDVFHHFYKWVEFIVYHQLLADIETLETLMNILLRYGKLFSQFINDHILFTKTFILIYTKILKESDNTAYSVTSFMPFWKFFMKNFSYTLNFDEDLRTDLGSVYEEEKAKVERFPKDKELVSLLNDDLHGNISNAKGLVCNFPEVFQTNLRVFFSSEEYSLSKKQARYMLLLIMNASTRDYNKFIAIYLKRKDFKMENLVHLISYKLLTLEQVQNVLGIDFILVLLSYKYEGYDLGFEYYRDHYVRLNYKLLLTACESKLNDHYTLFLEMLIQYGNLWKLYDITSSALLAVFNDSNVDNYKFLRSILFFGVKNYDKDEDIVMTDGISPHVWLDFTNIWLFQSYTKYILLDTLSSGEGLEKAKNFLFSMIEVTNYSCLCAQTFGRINDTDTINILIKIFERKFFDTCLYDKEISNQYLRVIIEVITFLSQQMAINSPSHQDMNVTFIESLRTISKHFAKKDEQELKNIRVKLDSFLKISIIHQTAIFEYVSNLIETNDIKIVNSLLDDLFTLFEKISFDLGLKLMLYEILSSLKSYCQYKSTTESGKGNKSVIVPTKLLELPPFQVSSFLKEEDPDDNEQQLSLGIQTEDDIPYGGRPLSSHPHSVNRCYQKQWFIYSKKTKEHWCRFYNEPYHCINNYQSESSSSFNNSCLNLSLFDARYEKRNPK
Length1369
PositionKinase
OrganismVanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) (Kluyveromyces polysporus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Saccharomycetaceae> Vanderwaltozyma.
Aromaticity0.13
Grand average of hydropathy-0.243
Instability index40.86
Isoelectric point5.93
Molecular weight160931.08
Publications
PubMed=17494770

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24755
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     790.23|     191|     197|     192|     388|       1
---------------------------------------------------------------------------
  160-  336 (256.97/144.38)	...........................LTKISKFIpHGLKRRQVLEqccMRQIPL............................kraiW.LLKCC.YSMEWKALSTKH.....LN.SKE.IN.SQLLKEWTENFIFMLEKLVFEM...S.QYYNDAAKLKVWKREI.YYFLKLLGNC.YTLELINK.D...I...LLHWLVEFISKIEIFEYLPLSLHILSLF..W..HD....ISNVN.......E.................SAPSAQPM.FLVTKISDTLLHKYIA
  341-  535 (222.55/134.39)	KSMINDekYIINDVKKNNKIKESI...LAVIRRLI.CDLFQRQLLE...VFLFPT..............................ssWdLYKPClYEI......TNQ.....LNdTPE.MV.AE.VKKKLELISYRNESLKLHYtsrS.HTPEDESGTNTSNDESkIEFIKL..NC.IDFELTEKlDdnpI...DFDW.ASFVDR.EIQNVSQIVQLIL.....WviHP....SRACR......yE.................GTQLVAKI.LLLTISSVEGLQEYVV
  536-  715 (159.09/83.95)	EDIIWS...VVFQISKYSEQKRSTfvsLPSLYKLL.NMLITYGIVK...V...PTyirklissgvlylpesndkffhcdalinlkisF.LMKSQ.YNMVLRNVIEYD.....AT.FYEkYNfDQLLSVTDELKQKILDSEELDM...SeQPYS....IKIMMAE...WYLGLI..CgGELEVVNK.Q...T...LMKN..........FNFFCIHFDVFHHFykW..VE...........................................................
  716-  889 (151.61/81.39)	........FI...................VYHQLL.ADIETLETLM...NIL.......................................................lrygkLF.SQF.IN.DHIL..FTKTFILIYTKILKES..dN.TAYSVTSFMPFWK.....FFMKNFS...YTLNF.DE.D...LrtdLGSVYEEEKAKVERF...PKDKELVSLL..N..DDlhgnISNAKglvcnfpEvfqtnlrvffsseeyslSKKQARYMlLLIMNASTRDYNKFIA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     165.61|      52|      70|      33|      91|       2
---------------------------------------------------------------------------
   33-   91 (76.89/60.98)	NKeMTYPDFDPwrHTKSEDDIMINFVS.KGYYTTPKVNFESISARSSLQEslpkLSNHLA
  106-  158 (88.72/49.71)	NK.IPYGNNDP..SSSSTQHQLFSLLSgPGFQLPNRVTLTDQRKDQWLQE....LSSPYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     148.96|      38|     248|     940|     989|       3
---------------------------------------------------------------------------
  908-  938 (39.24/11.51)	YKLLtLEQVQNVLGIDFILVL.LSYKYEG....YDL...
  952-  989 (68.65/48.36)	YKLL.LTACESKLNDHYTLFLEMLIQYGNLWKLYDITSS
 1205- 1234 (41.07/15.02)	.........NSLLDDLFTLFEKISFDLGLKLMLYEILSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.44|      24|      71|     995|    1018|       5
---------------------------------------------------------------------------
  995- 1018 (43.46/31.03)	FNDSNVDNYKFLRSIL...FFGVKNYD
 1069- 1086 (30.37/19.04)	FSMIEVTNYSCLCA.........QTFG
 1088- 1112 (32.61/21.09)	INDT..DTINILIKIFerkFFDTCLYD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.79|      15|     191|    1044|    1060|       6
---------------------------------------------------------------------------
 1044- 1060 (22.75/17.86)	QSYTKYilLDTLSSGEG
 1236- 1250 (29.04/16.48)	KSYCQY..KSTTESGKG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24755 with Med12 domain of Kingdom Fungi
Unable to open file!