<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24733
Description |
Mediator of RNA polymerase II transcription subunit 7 |
Sequence | MAAANEGVSPFPLPPIQYSKLYTDENIAQGNAPEPPPPIEGSYSVFGASFESDESIIRPLEVQGITRLYPQRRLDRISELKKLNHSILMNFLELLDTLIQTSSSAKRDAKLEDIRVLFINMHHLINELRPHQVYNSHPPPPI |
Length | 142 |
Position | Middle |
Organism | Nematostella vectensis (Starlet sea anemone) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Cnidaria> Anthozoa> Hexacorallia> Actiniaria>
Edwardsiidae> Nematostella.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.373 |
Instability index | 54.51 |
Isoelectric point | 5.69 |
Molecular weight | 16053.13 |
Publications | PubMed=17615350
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 RuleBase:RU364060
|
GO - Cellular Component | core mediator complex GO:0070847 IBA:GO_Central
mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP24733
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 49.05| 11| 101| 29| 39| 1
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6- 16 (23.60/10.52) EGVSPFPLPPI
29- 39 (25.45/11.85) QGNAPEPPPPI
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|