<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24728

Description Predicted protein
SequenceMSMSSDEVNFLVYRYLQESGFQHSAFTFGVESHIDQSSINGSVVPPGALVTILQKGVQYVEAEATVTEDGGLLDDGELDQLSLIDAALPDIISTRHTLLSNKGIKPETPYKNDNGSNEIYMHNNSVSNADSLQIDGSVNDIANQKALVLKGHQSEVFVCSWNPTQDILASGSGDGTARLWPMTDSGLGVPVVLAHNIKDQENHKNNSYDVTSLEWNSEGTYLATGCYDGCARIWDPEGQLVTTLREHKGPLFSVKWNKKGNHLLGAGVDKACIIWDANTWDVKQQFAFHQAPTLDVDWQNNNSFASCSTDKLIHVCRLGLDKPIKSFRGHMSEVNAIRWDPSGTLLASCSDDMSAKVWSLKEDMCVHDLQGHKKEIYTITWSPTGPGSANPSAPLLLASASYDTTVRLWDVERGGCLQVLSKHHEPVYTISFSPDGRYLASGSFDKRVHIWSTQTGNLVHSFQGSGGIFEVQWSPRGDKLAACFSNNTLCVIDVRTL
Length497
PositionTail
OrganismNematostella vectensis (Starlet sea anemone)
KingdomMetazoa
LineageEukaryota> Metazoa> Cnidaria> Anthozoa> Hexacorallia> Actiniaria> Edwardsiidae> Nematostella.
Aromaticity0.08
Grand average of hydropathy-0.320
Instability index39.21
Isoelectric point5.27
Molecular weight54536.28
Publications
PubMed=17615350

Function

Annotated function
GO - Cellular Component
histone deacetylase complex	GO:0000118	IBA:GO_Central
GO - Biological Function
transcription corepressor activity	GO:0003714	IBA:GO_Central
GO - Biological Process
histone deacetylation	GO:0016575	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP24728
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     362.86|      40|      40|     304|     343|       1
---------------------------------------------------------------------------
  149-  197 (43.16/26.00)	..LKGHQS...EVFVCSWNPTQ.........diL.ASGSGDgtaRLWPMTDSGLGVPvvlahnI
  198-  241 (47.95/29.81)	KDQENHKNnsyDVTSLEWNSEG.........tyL.ATGCYD...GCARIWD.PEGQL......V
  242-  272 (33.00/17.93)	TTLREHKG...P....................lF.SVKWNK...KGNHLLGAGVDKA......C
  284-  324 (51.26/32.44)	QQFAFHQA...PTLDVDW..........qnnnsF.ASCSTD...KLIHVCRLGLDKP......I
  325-  366 (61.55/40.62)	KSFRGHMS...EVNAIRWDPSG.........tlL.ASCSDD...MSAKVWSLKEDMC......V
  367-  417 (51.25/32.43)	HDLQGHKK...EIYTITWSPTGpgsanpsapllL.ASASYDttvRLWDVERGG...C......L
  418-  459 (52.75/33.63)	QVLSKHHE...PVYTISFSPDG..........rYlASGSFD...KRVHIWSTQTGNL......V
  460-  483 (21.94/ 9.13)	HSFQGS.G...GIFEVQWSPRG.........dkL.AAC..........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.84|      18|      46|      51|      71|       3
---------------------------------------------------------------------------
   51-   71 (25.10/27.54)	TIL.QKGVQyveAEATVTEDGG
   97-  115 (28.73/20.50)	TLLsNKGIK...PETPYKNDNG
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP24728 with Med16 domain of Kingdom Metazoa

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