<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24701
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MEDVENMDVDMDDLFGDGAGLSLPSRPPPSKELHQRIDELRGSGCCQGIAWSKWGSIASIAPNGNGLELRNLRCHPTDGTWGLSKPTLIPQLTNNLDGGPLKHLSWSPTGSELAVIDSAGRHGPAVKEASGFRYDASQAPILGPSHPIPSKSAFLYVTSNGSLRLLWQQGNNKWFESHTELESIVSSDDLITHAAICAERTPSLLIALATGSKQLRIIRAGIDWGMPQTQEKVNQMTLSLNASLRIKPLTVTSWMHDVPGDTLNPSHLESSMVQLSHLKFLSPCIDSKNHMTPPIVMAVRSYLPGPTSHYNQEVYSTVDRWEFRERNQQPVHSAFEHLSSRKGTDGPQSTKPVYTAQLKKLESFTVNKIVVAMQTIYIGRVICFAYSDSSVDYRDRITMNETFNDGDLDRVSHLSQIGFSYTEDEPCLQVVLSPSTCSLAQITNDGKVKWKQLDYHLGEIGSSMEDPRYAAMITALSTSCSTSVMIFINYDDIIATAHSFAKTKDNLAYDWLNELAKILKITVDYSEEAHYDVLIRNTTIQLCLSIQNSLGFRGDFNPRKFAGKFSWLVLQLRNIVVLVTMAANMKVPGPTHDKTSTPLDDPEVISALAGSVRWVLDLMAWIIDTLLDLPSSLPGELSLTDPAKLSLPDLLAHLHTQNNVTLHLLLSSPTRGFLTAICRRLQHLDYVARKAIATNTNAQNQPGGQGQQSISPALRSSYVQIAQLTSNCIVRIKTFETLLSSLTLSVKSAYASHKPPLPVNNSSGPSRNGLEMKMLFGGEIPTAFKPVIIDLFKGVQDNKKSNESNTAPDNAGTGHLSAVRLEIEPSDLWFADFTMLEVEEEEECVARRKNSGLTMDCFRKTWLSNPPPSSSKSSSTKNASSSAAAVSGDNHLAPIPGFAAFGLATPGTAGNGNANANANANANAVTTMTKRWRRCARCAAVMEDVLSQRPTLQWLVMQQRRCFCSGYWDTLQQGEMAA |
Length | 978 |
Position | Tail |
Organism | Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes>
Helotiales> Sclerotiniaceae> Sclerotinia.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.254 |
Instability index | 41.23 |
Isoelectric point | 6.37 |
Molecular weight | 107300.55 |
Publications | PubMed=21876677
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Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IBA:GO_Central
|
GO - Biological Function | |
GO - Biological Process | positive regulation of transcription, DNA-templated GO:0045893 IBA:GO_Central
|
Interaction
Repeat regions
Repeats |
>MDP24701
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 75.42| 21| 78| 17| 38| 1
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17- 33 (27.61/13.19) ........DG..AGL......SLPSRPPPSKEL
35- 67 (16.91/ 6.98) QRIDelrgSGccQGIawskwgSIASIAPNGNGL
91- 113 (30.90/12.64) QLTN..nlDG..GPL......KHLSWSPTGSEL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 99.59| 30| 78| 129| 165| 3
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130- 162 (45.79/28.45) SGFRYDASQAPILgpSHPIPSKSAfLYVTSNGS
851- 880 (53.80/22.17) SGLTMDCFRKTWL..SNPPPSSSK.SSSTKNAS
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 353.01| 117| 281| 168| 309| 7
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168- 309 (180.89/161.47) QQGNNKWFESHTELESIVSSDDLITHAAicaertpsLLIALATGSKQLRII...................RAGIDWgmpqtqekvnqmtlsLNASLRIKPLTVtSWMHDVPGDTL..NPS.....HLESSM...VQLSHLKF...LSPCIDSKNHMTPPIVMAVRSYLPGPTsH
444- 592 (172.12/120.20) NDGKVKWKQLDYHLGEIGSSMEDPRYAA........MITALSTSCSTSVMIfinyddiiatahsfaktkdNLAYDW...............LNELAKILKITV.DYSEEAHYDVLirNTTiqlclSIQNSLgfrGDFNPRKFagkFSWLVLQLRNIVVLVTMAANMKVPGPT.H
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