<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24693

Description Uncharacterized protein
SequenceMVCFMQGRTAYVSQVQPKEQPILVWDIKVKFRVIDRYKVIGFISSGTYGRVIKPLAEMDGRGIRHQEIQTDRKVNKFNILVFSHSAGGFMALCSELSHMNVIRLVEIILEDKCIFMVFEYAEHDLLQIIHHHTQPTRHPIPAPTVKSIMFQLLNGCQYLHANWVLHRDLKPANIMVSSSGEVKIGDLGLARLFNKPLHALFSGDKVVVTIWYRAPELLLGSKHYTPAIDMWAVGCIFAELLSLRPIFKGEEAKMDSKKTVPFQRNQMQKIVDIMGLPTKEKWPHLVSMPEYSQLSTLSASGHAKAGYSSLEKWYYQTINSSSTSVPVSNSSLGAEGYKLLSSLLEYDPEKRLTAQAALTHPFFSTGDKVSANVFEGVKTEYPHRRVSQDDNDIRTGSLPGTKRSGLPDDSRPAKRLKE
Length418
PositionKinase
OrganismSclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Leotiomycetes> Helotiales> Sclerotiniaceae> Sclerotinia.
Aromaticity0.09
Grand average of hydropathy-0.225
Instability index36.11
Isoelectric point9.19
Molecular weight47157.99
Publications
PubMed=21876677

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
nucleus	GO:0005634	IBA:GO_Central

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IBA:GO_Central
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IBA:GO_Central

GO - Biological Process
protein phosphorylation	GO:0006468	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24693
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.80|      27|      28|     280|     307|       1
---------------------------------------------------------------------------
  280-  307 (43.93/30.83)	EKWpHLVSMPEYSQLSTLSASGHAKAGY
  311-  337 (47.86/28.59)	EKW.YYQTINSSSTSVPVSNSSLGAEGY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.69|      38|      90|     111|     153|       3
---------------------------------------------------------------------------
  111-  153 (56.76/59.01)	DKCIFMVFeYAEHDLLQIIHHHTqPTrhpIPAPTVKSIMFQLL
  204-  241 (69.93/49.82)	DKVVVTIW.YRAPELLLGSKHYT.PA...IDMWAVGCIFAELL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24693 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FEGVKTEYPHRRVSQDDNDIRTGSLPGTKRSGLPDDSRPAKRLKE
374
418










Molecular Recognition Features






MoRF SequenceStartStop




1) LEKWYY
2) SRPAKRLKE
310
410
315
418