<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24682

Description Uncharacterized protein
SequenceMQPTRVFERHLVFKAYRKPGFVKTRPGGSQDVQAPETQRLNKLLNGGLYYMQVVGNVRERDFGSVTASTSSPSDALARGSDEGGEGTQHGQEALPPTTTRNGAAAAAAAAKGGYIAADQSWRLEFKDTPEAGARFGVTTRFVENSNLPSGNILPEMNAWGFNYVSEYVVEGHRFILDDIVLFLHHQMLLLDTSGAYILQASITVQDSGNPDMLKANSQRLLGLKEHLKSVVKLEPKDRLSLDTRSSAIESHKMKSAYGLCIFRLFLNRKSPDGGDISPPPLKRKAIGTATIIDNSLSQKKPEQVTWRTVNNSCIIGKYHQEQALEAVKSGKKRRIAAFDLDSTLVATKSGRRFPTNERDWKWWSPSVPDKLKQLNDEGYLVVVLSNQKAISLKKDLKGGRVESKSLSIFKQKVAAIMQTLDMPFSVYAATASDEFRKPRMGMWREMLDDHDLSVAGLLHLEQSIFVGDAAGREGDHSCVDRDFAANVGVPFETPEEFFLDEAPKPILRTFDPKAYIVDSSADEPTITFSKKSDVELVIFCGSPGSGKSTFYWRYLEPLGYERVNQDILKSLQKNIYKLESLWQSSPSNLLPDVQESINPESRSSLPGIAFGDFQRRFQVPVLSEGFQDITHVEFKFQGTPATKEVWGQYWV
Length651
PositionHead
OrganismAjellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) (Histoplasma capsulatum)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Onygenales> Ajellomycetaceae> Histoplasma.
Aromaticity0.09
Grand average of hydropathy-0.430
Instability index39.27
Isoelectric point8.09
Molecular weight72545.28
Publications
PubMed=19717792

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24682
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     177.57|      56|      60|     508|     567|       1
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  508-  567 (91.03/63.44)	RTFDPKAYIVDSS.ADEPTITFskkSDVELVIFCGS....PGSGKSTFYWRYLEPLGYERVnQDI
  569-  629 (86.54/49.82)	KSLQKNIYKLESLwQSSPSNLL...PDVQESINPESrsslPGIAFGDFQRRFQVPVLSEGF.QDI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     182.26|      65|     174|     205|     277|       2
---------------------------------------------------------------------------
  210-  277 (100.97/79.49)	PDMLK............ANsQRLLGLKEHLKSvVKLEPKDrLSL.DTRSSAI.ESHKMK.SAYGLCI...F...RLFLNRKSPDGGDIS
  368-  453 (81.29/43.67)	PDKLKqlndegylvvvlSN.QKAISLKKDLKG.GRVESKS.LSIfKQKVAAImQTLDMPfSVYAATAsdeFrkpRMGMWREMLDDHDLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.50|      17|      17|     315|     331|       5
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  315-  331 (29.01/21.91)	IGKYHQEQALEAVKSGK
  335-  351 (27.49/20.36)	IAAFDLDSTLVATKSGR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24682 with Med18 domain of Kingdom Fungi
Unable to open file!