<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24665

Description Uncharacterized protein
SequenceMLSKTKSRNRLLLSNHKSNTGGSATRDELLRLKYLMIKPDLPVYTLDDTTTTVVSTPRTATEPKITTEPTYPDFTPWKDLTQVSEQKESTGTGTKTGTGTGSGTGSIDQSRSQVPPSGEAAEKEHVYFNKGYAEAPQVNNEYYSARNLLQSTLLKSNDNCNTVISELSQHLTNSFRSRNEVINRIKSDSAHFRLPQRVTLTAAKRDMWLTELSNPNIPLQKIGEKIPHGMKNKTLIDAVITKKIPIDRALWLTKCILYGEIIALRRKIQSRLNLNGGGNGSVSGNTGMGVGSSALASEWTVFEKYEIHWFHDWTQQVTEYIFKFSKEMNSITNHEYKGVYMSRLSYLLDYVQHLYIEALVDPSYFQIQILKPFRDNIPKDKKLLESITINTNQDDDEADNCEDGQDEKEVHDASDRQRALVKVDFSQTLFALTLLKIFWKDLLQHENVIKEVAELLLLNYMIIANLVLITGIRLPQTLGSKLTGSIKDLIVYLFKHDVNIFVIPESWHHVESLLNEILLLHLEACTLEQKGKLLKQLDLIKFRNESLVLNTKGETGSASGSGSEGEGVLGNDTHSPKDGASLLTTSIRHKRESSSNAALIINNLDNGRLNDKMAEMFLPYNNDNFTVAESSFTWKQNLSILIVWCCTKWRSRSNKSEEIQIACSFLEKSISKIGLDRYQRNELENEILENVFALIDDKEELIFIDQSQLYCLINELYRAKICSVSSYMRKLISSGVLSSPELFSDDEQIPMVIQAHLNILQCLPVENNRQRNNLLKKWRCGTLEPEKLQETKQLFALNFIDRIAKNEDILSHINDLSNAVTHLTYGSKIQLTNWFAKELNAVFKRTTKLIRLSPTIVYAMYLLHKDCNNLLAFFKFVVPTILKNESGIIFLHHNALYLVARLVMKHFRLIKQFSSYSETSALTLFLLILQNYREAEEYSSYYNFEQVWNFMDHAISRTNAKLNLVLNQDHNQKRRKVDNNSIGTNDSVQSVPPTVRSTSEFPDTPMRINVEDISNTTMVNANAGSQTINTADDFFESLANLRRLSSNYHLENDSTSFSSQHLSLSVDELLESWILQNSPNSKDYNVPAKEKEEKEIQTVQLLKLKLANESASDEDNNNANNNANNKSVVNLKENIIFKMKNLLNQVDNSEQRCAMLKKLVIYDIVSVGDIIKIMFSLDKAFSINYKLFNSMLLNSGSGSSSGYENNLYSNFNSDRNQFISPIQQELFDIAVGFYKRKNRKEFFHLILKSLTSDGPLFTNDLMINHEFVTLEYLRDILARDASFLNESLFAQLSRDDSIELLNLLLGRNNNNYILSLEGFENEIRHLNEFNIGGYQILVALLSKLLDVVDLSVRKLRWEQFVAAMLNCSEDFQKSSSNTDVDYNDERIKTAFKLFEFVSWDQKAILLEVFEEVFLSQGNDARGENQGVVMLSKPRLLGIDLFFTNFIYNSSHKVGISEHLINSISNFVKSMLSTLDIAKSEVVLGDRSREYLLATLFKILIIHRESLCNTLSSSLSSSLSISSSSPSVLSSTSSPSSISGGTCETLVGNLIEMLLARYLAEPNNKWKVLLFDMLSLMKLSISTRRNSITNIDFATSPNLGSTPNEFHPVATSNVTTTVSAQIGTLFELPKMKDVNELKSELDDDMIRSIIMLDLEELKYGGDVSTFNDPSLVIDSTRRDVFAMSPFVSNLLSVNKSGDYQKTSNGIDIKPFQMKSYEIIEDITVSTVNDACLNLLLFDSYLTRENPV
Length1746
PositionKinase
OrganismLodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Lodderomyces.
Aromaticity0.08
Grand average of hydropathy-0.283
Instability index37.36
Isoelectric point5.79
Molecular weight197995.65
Publications
PubMed=19465905

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24665
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.74|      29|     460|      78|     106|       1
---------------------------------------------------------------------------
   78-  106 (49.72/35.40)	KDLTQVSEQKESTGTGTKTGTGTGSGTGS
  535-  563 (50.02/35.66)	KQLDLIKFRNESLVLNTKGETGSASGSGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.40|      12|     460|    1215|    1229|       6
---------------------------------------------------------------------------
 1215- 1226 (21.17/18.33)	RNQFISPIQQEL
 1239- 1250 (20.23/ 6.54)	RKEFFHLILKSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.28|      35|     184|     691|     727|       7
---------------------------------------------------------------------------
  691-  727 (51.21/47.58)	VFALIDDKEELIFIDQSQLYcLINEL....YRAkICSVSSY
  878-  916 (55.07/39.19)	VPTILKNESGIIFLHHNALY.LVARLvmkhFRL.IKQFSSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.85|      61|     637|     793|     870|       8
---------------------------------------------------------------------------
  429-  499 (93.92/51.94)	LFALTLLKIFWK..DLLQHENVIKEvaellllnymIIANLVLITGIRLPQTLGSKLTGSIK...DLI.........VYLFKHDVN
  794-  868 (87.93/79.60)	LFALNFIDRIAKneDILSHINDLSN..........AVTHLTYGSKIQLTNWFAKELNAVFKrttKLIrlsptivyaMYLLHKDCN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     158.24|      52|     380|    1270|    1337|       9
---------------------------------------------------------------------------
 1280- 1336 (80.80/57.26)	DASFLNE.SLFAQLSRDD....SIELLNLLLGRNNNNYILSLEGFEneirhLNEFNIGGYQI
 1661- 1717 (77.44/33.96)	DVSTFNDpSLVIDSTRRDvfamSPFVSNLLSVNKSGDYQKTSNGID.....IKPFQMKSYEI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     226.43|      73|    1344|     141|     216|      13
---------------------------------------------------------------------------
  141-  216 (111.15/81.01)	EYYSArNLLQSTLLKSNDNCNTVISELSQHLTNSfRSRNEVINRIKSDSAhFRLPQRVTLTAAKRDMWLTE.LSNPN
 1489- 1562 (115.28/70.26)	EYLLA.TLFKILIIHRESLCNTLSSSLSSSLSIS.SSSPSVLSSTSSPSS.ISGGTCETLVGNLIEMLLARyLAEPN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.75|      28|     720|     382|     411|      14
---------------------------------------------------------------------------
  382-  411 (44.48/36.08)	KLLES.ITINT.NQDDDEADNCEdgQDEKEVH
 1068- 1097 (38.27/23.50)	ELLESwILQNSpNSKDYNVPAKE..KEEKEIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.66|      10|      15|     947|     957|      15
---------------------------------------------------------------------------
  947-  957 (15.94/13.90)	VWNfMDHAISR
  965-  974 (18.72/10.18)	VLN.QDHNQKR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24665 with Med12 domain of Kingdom Fungi
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