<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24654

Description Uncharacterized protein
SequenceMGVFSIFGSNSHGFDPEKFEKELNTIAENINKTKQQLLLLSSNKRRTLRRIEFPTAVVYILILFYSYISISRDVIATNRIQWFIKGQTKYSLGTLIGFPVVLIIIVKLIRFVYQYLINGKEKQLVLLKKKHTAKIEELKKITNFNATNELLNKYGDEKIGGQTRLSPQQLLKQQQQQQQQQQQQQQQQNQKRKDKKLSKSEALRAQALKELNLKDPSRNIEGAALAQDPSISKSPAPVTSSAQSRPASPSLGETKTRPRTLQDRLLDLLIGTDNSEAVENRYALICSHCFAHNGLAPPHCEDPSLVKYQCWKCGQLNGKGVLFADPPQQIQQQHSDESGIQSPGDFESSELAEILGDKKAEKKQQVESKDSWELDLAENAKGIAEEFENNEEKKQI
Length396
PositionTail
OrganismLodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Lodderomyces.
Aromaticity0.07
Grand average of hydropathy-0.651
Instability index56.88
Isoelectric point9.09
Molecular weight44844.49
Publications
PubMed=19465905

Function

Annotated function Plays a role in determining ER morphology. 
ECO:0000256	RuleBase:RU367073
GO - Cellular Component
endoplasmic reticulum tubular network membrane	GO:0098826	IEA:UniProtKB-UniRule
integral component of endoplasmic reticulum membrane	GO:0030176	IEA:UniProtKB-UniRule
GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW
GO - Biological Process
endoplasmic reticulum tubular network maintenance	GO:0071788	IEA:UniProtKB-UniRule
positive regulation of endoplasmic reticulum tubular network organization	GO:1903373	IEA:UniProtKB-UniRule

Interaction

Binary Interactions











Repeat regions





Repeats

>MDP24654
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.75|      13|      14|     168|     180|       1
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  168-  180 (21.36/14.09)	QQLLKQQQQQQQQ
  184-  196 (21.39/14.13)	QQQQQNQKRKDKK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24654 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQALKELNLKDPSRNIEGAALAQDPSISKSPAPVTSSAQSRPASPSLGETKTRPRTLQDRLLDLLI
2) LFADPPQQIQQQHSDESGIQSPGDFESSELAEI
3) LSPQQLLKQQQQQQQQQQQQQQQQNQKRKDKKLSKSE
205
322
165
270
354
201










Molecular Recognition Features






MoRF SequenceStartStop




1) ESSELAEILGDKKAEKKQQVESKDSWELDLAENAKGIAE
347
385