<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24646

Description Uncharacterized protein
SequenceMNINNVQQQQQQQQQQQQQGGNGNGANFGRATSWQGMYTGEERQRVVLIIMNTLSDLHGSNPSFDFQRLTKMAQDFEKIVYEKSPSREEYLKAIKLKVNQLRLQKQQLGGGVASGTGGGNTGVGNIVGGTAAQSLPQQQQQQQQQQAVVRNNFNNNGNGNANISQNAQFLNLQAQVRAQSQAQIQARQQQLRQMVNKNQQNQQNQQNQQNPQGQQNVLMQQNQRPPQQHMPQTQPLSQQQPQPQQQPQPQQQVRAGSGNGNTAGTQQVPPQLLQLIRNSPIPPPLLSKIPNLPKGITTWNQIFDCIRRKVISQDVLPLIRDIHSTHMQLVMRQQQQKQSMTNNPNAVTGSGGVPAAGTTQIGPNAGSVDANSLQLSGKQTNNVNNVNLGNLTPQQREQFLQGQRVSQNQQTSSTNIPPNMMINAGLQPQQQPQSVQPTPTMSSQNFQQQKQQQFQQPVPQVQQTQQLSQPQQQQQQQMRQQQISQQAPPPPPSQQQQQQPQQQQQQQRPQSVPQPPPQGQVGQKPPQFQITPQDFAKYSNDALAVLSRLQQQKQIEGQIDSNMRDTFIRKYILHQKTQLWKQHQAAQGNTGMLGTNTQSQAPLQQPQQPQQPQPQPQPQPQLPPQQQGPQQQQNISGFQATARPSAQFNQGNPASMQSNVPQSLPMMNNNNNNIVNSNNMNPQLNNNAVINPHSSPVMPQHAMNQNVVSGPVPINQQGKSLNGRVGPGGNIGVAALFPPLTDEAKLRLRQLIEEVSRNNVLLKDVTGLLSQKDKTNVRNAMNSIQEQFGNVDSIISYFFLLTKNAEGTKRLIQMKYMTKNILENLHRGVYLAAPDLLEKLRNQYAKYFDYVKEQINLRRQQVSANANVGASAVADMSHQLTPSLQPPPVRQVPQQLQQQPPPSSQQQQQQQQQHQQGNILTTAARPSQPFPNQNPQSSPQMFTPSLPPAGLPPQNWANVPGANPLMVNMQQHPPPQSQQQPNIVPNTSNVPISTIPQKVPAPQSKAKKPPPKKKRTSSATAATPNALASSIKTPHNVNTPQIQTSGQSPQTKTTPLGGSNAASGTVPTPKATSNGSGTTAGLGGGATEATTYATAPEMDIFSSSSDLIQRKELSVTDPVQFFAETMKKLLNIEQNSDASDPDETEKFKEENDSAAVLLAITSSFKQVRGIDDMCVDSIF
Length1179
PositionTail
OrganismLodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Candida/Lodderomyces clade> Lodderomyces.
Aromaticity0.04
Grand average of hydropathy-0.930
Instability index69.81
Isoelectric point10.05
Molecular weight129879.34
Publications
PubMed=19465905

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24646
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     999.13|     126|     126|     393|     518|       1
---------------------------------------------------------------------------
    8-  101 (84.23/11.86)	...........................................................................QQQQQQ.....QQQQ....QQGGNG.......NGANF.............G....RAT.............................................S..............WQ.............................................GMYTGEERQRVVLIIMNTLSDLHGSNPSFDFQRL.....TK....MA.........QDFEKivyEKSPSREEYL.K...AIKlKVN.QL..
  102-  221 (121.01/21.44)	..RLQKQQLG........G.GV....ASG.....TGG................GN..........TgvgnivGG.TAAQSL.....PQQQ....QQQQQQ.......QAVVR.............N....NFN.............................................NNgngnanisQNAQFLN.............................................LQ..AQVRAQS..........QAQIQARQQ....Q.L.RQM....VN.........KNQQN...QQNQQNQQN..P...QGQ.QNV.LMQQ
  222-  331 (129.91/23.76)	NQRPPQQHMP........QtQP....LSQ.....QQP................QP.....................QQQPQ.....PQQQvragSGNGNT.......AGTQQ.............V....PPQ...........................................................LLQ.............................................LIRNS........PIPPPLLSKI...P.NLPKGI.....TT....WN.........QIFDC...IRRKVISQDVlPlirDIH.STHmQLVM
  332-  469 (166.04/33.18)	RQQQQKQSMT........N.N............................................P......NAvTGSGGV.....PAAG....TTQIGPnagsvdaNSLQL.............S....GKQ................................tnnvnnvnlgnltPQ........QREQFLQ.............................................GQRVSQNQQTSSTNIPPNMMINAGLQPQQQPQSVQPT.PTM....SS.........QNFQQ...QKQQQFQQPV.P...QVQ.QTQ.QLSQ
  470-  600 (174.44/35.36)	PQQQQQQQMR........Q.QQ....ISQ.....QAP................PP..........P......PS.QQQQQQ.....PQQQ....QQQQRP.......QSVPQ.............P....PPQ..........................................gqvGQ........KPPQF................................................QITPQDFAKYSND...ALAVLSRLQQQKQIEG.QID.SNM....RDtfirkyilhQKTQL...WKQHQAAQGN.T...GML.GTN.TQSQ
  602-  723 (160.21/31.66)	PLQQPQQPQQ........P.QP....QPQ.....PQP................QL..........P......P....QQQG.....PQQQ....QNISGF.......QATAR.............P....SAQ................................fnqgnpasmqsnvPQ........S....LP.............................................MMNNNNNNIVNSNNMNPQLNNNAVINPHSSP..VMPQ.HAM.....N.........QNV..........VSGPV.P...INQ.QGK.SLNG
  738-  909 (76.98/ 9.97)	PPLTDEAKLR........L.RQlieeVSRnnvllKDV................TG..........L......LS.QKDKTNvrnamNSIQ....EQFGNV.......DSIIS.............YffllTKN.............................................AE........GTKRLIQmkymtknilenlhrgvylaapdlleklrnqyakyfdyvkeqinlrRQQVSANANVGASAV.......ADMSHQLTP.SLQPP.P...................VRQ...VPQQLQQQPP.P...SSQ.QQQ.Q...
  910- 1125 (86.31/12.40)	.QQQQHQQGNilttaarpS.QP....FPN.....QNPqsspqmftpslppaglPPqnwanvpganP......LM.VNMQQH.....PPPQ....SQQQ.P.......NIVPNtsnvpistipqkvP....APQskakkpppkkkrtssataatpnalassiktphnvntpqiqtsgqsPQ........TKTTPLG.............................................GSNAASGTVPTPKATSNGSGTTAGLGGGATEATTYATaPEMdifsSS.........SDLIQ...RKELSVTDPV.Q...FFA.ET......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.90|      15|      15|    1135|    1149|       2
---------------------------------------------------------------------------
 1135- 1149 (25.71/17.79)	NSDASDPDETEKFKE
 1152- 1166 (23.19/15.37)	DSAAVLLAITSSFKQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24646 with Med15 domain of Kingdom Fungi
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