<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24640

Description Uncharacterized protein
SequenceMSKNKSRNSLLFSSNRSTQSASDKDELIAMKFSMDKPNLDIYPLSVGVEDKKESNTKHSYPDFKPWRESTPTDPGSFNDAEASKENNASYLNKGYYEPPAVPNEYSSARSLVQASLFSSSDSPNEALEDLSRMMAGAFKSRNESINKIKHDTHQFKIPPRVTLTASKKEAWLRDLADPEIPLSKISGKLPHGIRNKILVESMCNKNVPLPRAIWFTKCILYSEIQALKKKYHAKLTGPRFTSTIVNYELHWLHEWTQQVADYVQKFAREMNGISSTEKKSAYMSKLSYLLRYLQSLYLECLIDRRLFLSCIINILREGLPLEAKQVSELISMSWEDSDKHLDLLNGIEKHYGQRLIALMLIKSFWKVILPLDYLCKELSEALLLNYYFLRRASTFNPKQPPQKQNSNALPSKLKSTILDLVAESIKYLFKHNSNTFILPNYWVLTSEELSSILLNDKDSKMEEVQLIKDQLKTIKYRNESLILNSKHIQAVSNEQQHDFATKAKYSSQTTKDESVSTEADYWFINRSQGDLLKIVDSLDRYRLDDGLAILLRPQQENSRWRIYLKLLIHWCITDYRDSAISSQGILIACNFIKGKVLYKRIDSQKKAEFESEILEIIYQVVSDPTAKIKSYSLYVLINELYQLKIITISSYIRRLIASGVFYVSPEESSQKLILNNEISTHLSILKNLPVTNNKQCDSILRKWVSDDFNFKTKFDTGKIILQENIIENLLESKEKAFVQGSGIEYFQNLEVGLKFLLINWLTTQLKNTIMSSTKLIHVYPSTISILYDLFCACDNLTVFFKGIIKLVLRNDGGIIIFYLDSLYLIAKLVVRHFKLIKYITTSPSEVPTILELMKLILLHYKDLQSRDFDYTKFRSIWIFFESMISSSELQFSSVWDHKTMQKPKNKGTVALSSTEIIAEWSNPWQNVSPSTEDLKTVLDDIIAEPVPLLSEEELGESCKTLKVTLASNTVLDNFSQLLIKFDETLGNLQYDEEVSLIRLIVHHDRLLKASKESTDVSTLIKAHIGEMSDSTKILLLLKKLLCYELIDYSLVVQLLTSENYGFSAESNYDTIMQVLFGKNVRTGIFSNQQVMLQILRETYLTKNSVSVLPIILKSFKRTQSHVPVEQILKENMLSVLRGCCLYHIRDVIDELVKHLTNSEIIRVCNELAGISPDSSISLINDIPVLGKVANEFSLPICQILLRTITSNELEYLGTSEASRQIEIITESLLYSFHSDLLKDNSFFGEITNYCGPEYKYMFLRVLETKFLTCTKFDGGRLSLCTEQGENLFPILKDFFKKFSVSYTRDAVTGELFTELNKFLQELLPIAKSPSIDENTAVDLQNAISVYLRIIIIHKVPLITTIITKDGEKFTFVRNLIELLKSNFLSSNNESLRILLYDLLLLMKSSLTSALTLQANGMFENSPAATQDDFNGNQEIDAPPTEQHSKQLFVNDAISSISRIFNLPEPSTSNPFEAYKKEEIQACSIMLDEEELNCGSDFAAFNDSGLVAVPVDKKRSSSEKVKPFKIKSFEIIEGSTNGSEDLNDSCINLSMFGAYVLRENPL
Length1561
PositionKinase
OrganismMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Meyerozyma.
Aromaticity0.09
Grand average of hydropathy-0.186
Instability index46.82
Isoelectric point6.22
Molecular weight178293.91
Publications
PubMed=19465905

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24640
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     365.13|      78|     154|     660|     737|       1
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  660-  737 (124.58/82.32)	VFYVSPEESSQKLILNNEISTHLSIL..KNLP.........VTNNKQCDSILR..KWV........SDDF.NFKTKFDT..GKIILQENII........ENLLE.SKEKAF
  743-  815 (106.34/69.03)	IEYFQNLEVGLKFLLINWLTTQ...L..KNTI.........MSSTKLIH.VYP..STI........SILY.DLFCACDN..LTVFFK.GII........KLVLR.NDGGII
  816-  891 (88.36/55.92)	IFYLDSLYLIAKLVV.....RHFKLI..KYI..........TTSPSEVPTILElmKLIllhykdlqSRDF.DY.TKFRS..IWIFF.............ESMIS.SSELQF
  927- 1012 (45.86/24.94)	...VSPSTEDLKTVLDDIIAEPVPLLseEELGescktlkvtLASNT...........V........LDNFsQLLIKFDEtlGNLQYDEEVSlirlivhhDRLLKaSKE...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.08|      30|      77|     145|     174|       2
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  145-  174 (53.27/34.97)	INKIKHDTHQFKIPPRVTLTASKKE.AWLRD
  224-  254 (49.81/32.22)	IQALKKKYHAKLTGPRFTSTIVNYElHWLHE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.98|      19|     282|    1091|    1112|       3
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 1093- 1112 (27.59/24.52)	QILRETYLTKNSVSvLPIIL
 1377- 1395 (30.40/14.62)	ELLKSNFLSSNNES.LRILL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.28|      18|      55|     371|     388|       6
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  371-  388 (32.01/19.67)	LDYLCKELSEALLLNYYF
  425-  442 (35.27/22.48)	IKYLFKHNSNTFILPNYW
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.77|      26|     297|      21|      49|      10
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   21-   49 (35.38/32.81)	ASDKDELIAMKFSMDKPNLDIypLSvGVE
  323-  348 (45.39/28.12)	AKQVSELISMSWEDSDKHLDL..LN.GIE
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     179.68|      53|     726|     505|     557|      11
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  505-  557 (89.38/61.68)	YSSQTTKDESVSTEADYWFINRSQGDLLKIVDS..LDRYRLDDGLAILLRPQQEN
 1232- 1286 (90.31/62.41)	FHSDLLKDNSFFGEITNYCGPEYKYMFLRVLETkfLTCTKFDGGRLSLCTEQGEN
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24640 with Med12 domain of Kingdom Fungi
Unable to open file!