<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24630

Description Uncharacterized protein
SequenceMYNPPMNQQMNSWHSRYSGADRQKVVQLLSSALKDIQSSNYDPQRAATMAQEFEKYTFMKSTSRDEYLRLIEQKVMQLRENSRRKSMMNGNVNMNGMNSNMNGMNSNMNGGMNMNSNMNSNMSNMNMSGMNSTMGNMNSNMNQNVNQNINPSVNQTLNQSVSSGMGQNMGQNSSPNMNMNMNQSSPNQRFMQQPMRQQNPQPSSSPNLQQATTQPSGSQLQQVSNMIRNTPIPPALLSQIPHLPPNVNTWNQIFDCYQKKIIPAVAMPVIKEMHGAHVSIVMRQHQQRLNRGGNMNVNMNNSTNTNLNTQNMDMSTGNMNGTNLNVNANNINSNMSVQQRQQMLQNQMRNSQMLQQQQQQQQPPKPPNLTITPQDMAKYSGDAMNLLSRLQSNGSISPNLDQVQKESFIRKYISHQKATAWKQQEAARRMQQSQPPASAPQQQFPPSSQFSSQEPQALPAQPVPPQSAPAQASPMMNMHMSPVPPPQQQQQQQRMQLPPLNDEMKMKLRQLVEEVARNSIALKDVTMSLTGPQKDAVRDAVMRISQSYSNVDSIISYFYILTRNAEGTKRLIQMKYMTKNIMESLQKGVYLAGPDLLEKLKLQYQKYFEYVKEQFAARKNQMNQNQNAMGMMNQSQMPSNIPAQVSEQTQTQNSNLLFNRLPVQPQTQQSTSLAPPTSQSTKPPSTHPGQTPRFSSPMMAGSPMVQRATPKPQAKKPPAQSRRKGSTKSVSNAGGIPTPAANAGTPGSGVGASRSPNSFPTPHGQPGSNKNTPQEYSPAKGGSIDVPLEEIFGRSSTDTRVAHRRSLSTSDPEKFFYATLANLLELGEDAADKASVHGHSPLSPVQHGEWSCSVRPEAITSSFRQVDLIRDVVASDIIQICEVLSEPPKREAVDDLGGDVKRSDWLHEPISFEEWRKNFDQVESKSNIIV
Length930
PositionTail
OrganismMeyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Meyerozyma.
Aromaticity0.05
Grand average of hydropathy-0.850
Instability index62.84
Isoelectric point9.74
Molecular weight103761.84
Publications
PubMed=19465905

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24630
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.64|      17|      18|     177|     194|       1
---------------------------------------------------------------------------
  168-  193 (23.15/ 8.80)	NmgqnsspnMNMnMNQSSPNQRFMQQ
  628-  644 (29.49/ 8.64)	A........MGM.MNQSQMPSNIPAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.42|      15|      21|      97|     117|       2
---------------------------------------------------------------------------
   97-  111 (34.20/17.81)	MNSNMNGMNSNMNGG
  130-  144 (30.22/ 6.40)	MNSTMGNMNSNMNQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     212.02|      28|      28|     432|     459|       3
---------------------------------------------------------------------------
  194-  224 (34.88/10.73)	PMRQQnpQPSSSPN.LQ....QatTQPSGSQLQQ...VS
  445-  473 (44.24/15.86)	PPSSQ..FSSQEPQALP...aQ..PVPPQSAPAQ...AS
  474-  497 (32.71/ 9.54)	PMMNM..HMSPVP.............PPQQQQQQqrmQL
  675-  696 (35.50/11.07)	PPTSQ...STKPPST...........HPGQTPRF...SS
  697-  716 (29.79/ 7.94)	PM......MAGSPMV......Q..RATP..KPQA...KK
  746-  777 (34.91/10.75)	PGSGV..GASRSPNSFPtphgQ..PGSNKNTPQE...YS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     131.69|      28|      28|     292|     319|       4
---------------------------------------------------------------------------
  150-  176 (28.85/ 7.89)	NPSVNQTL...NQS......VS..SG..M........GQnmgqNSSPN.
  300-  328 (43.84/16.12)	NNSTNTNL...NTQNM...DMS..TGN.M.......nGT....NLNVNA
  329-  361 (32.00/ 9.62)	NN.INSNMsvqQRQQMlqnQMR..NSQ.M........LQ....QQQQQQ
  362-  400 (27.00/ 6.88)	QPPKPPNL...TITPQ...DMAkySGDaMnllsrlqsNG....SISPNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.81|      10|      15|     648|     657|       5
---------------------------------------------------------------------------
  648-  657 (18.05/ 8.71)	QTQTQNSNLL
  664-  673 (18.76/ 9.39)	QPQTQQSTSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     189.62|      62|     517|       4|      93|       6
---------------------------------------------------------------------------
    4-   76 (102.98/107.19)	PPMNQQMnswhsrysgadRQKVVQLL......SSALKDIQSSNYDPQ....RAATM..AQEFE......KYTFMKSTSRDEYLRLIEQKVM
  498-  577 (86.65/44.56)	PPLNDEM...........KMKLRQLVeevarnSIALKDVTMSLTGPQkdavRDAVMriSQSYSnvdsiiSYFYILTRNAEGTKRLIQMKYM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.69|      17|     204|      77|      94|       7
---------------------------------------------------------------------------
   77-   94 (26.88/12.42)	QLRENS...RRKSMMnGNVNM
  112-  127 (26.28/ 8.56)	.MNMNS...NMNSNM.SNMNM
  281-  299 (25.53/ 8.13)	VMRQHQqrlNRGGNM..NVNM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.94|      15|      31|     792|     806|       8
---------------------------------------------------------------------------
  792-  806 (26.37/19.71)	F..........GRSSTDTRVAHRRS
  816-  840 (18.57/11.74)	FyatlanllelGEDAADKASVHGHS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24630 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MHGAHVSIVMRQHQQRLNRGGNMNVNMNNSTNTNLNTQNMDMSTGNMNGTNLNVNANNINSNMSVQQRQQMLQNQMRNSQMLQQQQQQQQPPKPPNLTITPQDMAKYSGDAMNLLSRLQSNGSISPNLDQVQKESFIRKYISHQKATAWKQQEAARRMQQSQPPASAPQQQFPPSSQFSSQEPQALPAQPVPPQSAPAQASPMMNMHMSPVPPPQQQQQQQRMQLPPLNDEM
2) RKNQMNQNQNAMGMMNQSQMPSNIPAQVSEQTQTQNSNLLFNRLPVQPQTQQSTSLAPPTSQSTKPPSTHPGQTPRFSSPMMAGSPMVQRATPKPQAKKPPAQSRRKGSTKSVSNAGGIPTPAANAGTPGSGVGASRSPNSFPTPHGQPGSNKNTPQEYSPAKGGSIDVPLEEIFGRSSTDTRVAHRRSLS
3) RLIEQKVMQLRENSRRKSMMNGNVNMNGMNSNMNGMNSNMNGGMNMNSNMNSNMSNMNMSGMNSTMGNMNSNMNQNVNQNINPSVNQTLNQSVSSGMGQNMGQNSSPNMNMNMNQSSPNQRFMQQPMRQQNPQPSSSPNLQQATTQPSGSQLQQVSNMIRNTPIPPALLSQIPHLP
273
618
69
504
808
244










Molecular Recognition Features






MoRF SequenceStartStop




NANANA