Description | Mediator of RNA polymerase II transcription subunit 31 (Fragment) |
Sequence | SVPTRWEIELEFVQSLSNIQYLNHLAQQGYLNDENFINYIKYLNYWKEPQYARYLVYPNCLHILTLLQDEQFRSNIVNPDFMNSLMNDMVQRWQNND |
Length | 97 |
Position | Middle |
Organism | Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) (Yeast) (Pichia stipitis) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Debaryomycetaceae> Scheffersomyces. |
Aromaticity | 0.15 |
Grand average of hydropathy | -0.581 |
Instability index | 62.55 |
Isoelectric point | 4.77 |
Molecular weight | 11867.19 |
Publications | PubMed=17334359 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364129 |
GO - Cellular Component | core mediator complex GO:0070847 IEA:EnsemblFungi mediator complex GO:0016592 IEA:EnsemblFungi |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | DNA repair GO:0006281 IEA:EnsemblFungi meiotic gene conversion GO:0006311 IEA:EnsemblFungi meiotic sister chromatid segregation GO:0045144 IEA:EnsemblFungi regulation of transcription, DNA-templated GO:0006355 IEA:InterPro transcription by RNA polymerase II GO:0006366 IEA:EnsemblFungi |
Binary Interactions |
Repeats | >MDP24616 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) ENFINYIKYLNYWK 2) IVNPDFMNSLMNDMVQRWQNN 3) VPTRWEIELE | 34 76 2 | 47 96 11 |
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