<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24546

Description Uncharacterized protein
SequenceMQRYHAGSCTSAVNNSAIGGPSSRDNGKSDSSLPANFPVNSRRQQPQLAPYKLKCDKEPLNSRLGVPDFHPQTPNCPEETLTREYLQSGYRDTVEGLEEAREISLTQVSNFNKTVVLNCKEAIRKRLRAINESRAQKRKAGQVYGVALSGSQIAKPGVFPELRPCGEDFRKRWIEGLSQPHKRLRSLADQVPNGYKKASLLEVLIRNNVPLLRANWFIKVTYLNQVRPGSVGISSGTADKIQLSRSEVWTKDVINYLQTLLDDFVSKSTSHSTPHTRERSAQMLYTGSMQHKNDPLLSVSDGEDPSLHFRWWYIVRLLQWHHTEGLLLPSLVIDWVLSQLQEKDLLEVWQLLLPIIYGFLETVVLSQTYVRTLAGIALHVIRDPAPGGSDLVDNSRRAYTTYALIEMLRYLILAVPDTFVGLDCFPLPSSVVSHTINDGNFVLKSIEAAGTIKNSTDDFGHVVSSIHKNAEYLAKASCSGYPDRCLAKVAKALDESLVLGDLRGAYKFLFEDFCDGTVSEGWVAKVSPCLRLSLKWFGTVSSSLVYSAFFLCEWATCDSRDFRTTPPCDVKFTGRKDLSQVHIAVRLLKMKMRDMNISLRQTNGRNQRVSHLAKCSNQHQHNQNHVGNASKVKSSSKRVGWSIFESPGPIHDIIVCWIDQHVVHRGEGFKRLHLFIVELILAGIFYPVAYVRQLIVSGIMDMNVNVVDLERRKRHYHILKQLPRCFMHEALEESRIVEGTQLDEALQIYLNERRLILRGVLSEHRDDASISAKKRKHYPAYAKDGASTVSIDQWKTVLTNTVTSKSAKNDVNIEELKAAIVSMLQLPNSLSNLSTVGSDDSEGSIRRPIWSHHSKIDPVEASPGLQESRRVKRQKLSEERSSFVQGHSAVVPDDDDSWWVKKGMKSSEPLKVEQPPKSVKQVTKPRQKNVRKTQSLAQLQASRIEGSEGASTSHVCDNKVSCPHHRTALDGDKLKSVDSQTCHCGDIVSIGKTVKRLRFVEKRAMGLWLMTVVRQVVEENEKNVGKVGQVGRPYSIVDERSSIRWKLGEDELSSILYLMDITDDLISASKFLIWLLPKVLSSPNSTIQSGRNVLLLPRNVENQVCDVGEAFLISSLRRYENILVAADLIPEVLSSAMYRAAAIIASNGRVSGSGALAFAWYLLKKYSSVASVSEWEKNFKATCDARLSSELESGRSVNGEFGLPLGVPLGVEDPDDFFRHKMSGGRLPSRVGSGMRDIVQRNVEEAYHYLFGKDRKLFAAGGTPKGLVLEKWDNGYQIAQQIVMGLIDCIRQTGGAAQEGDPSLICSAVSAIVSSVGPTLAKMPDFSCGINHSNTTNATSSLSYARCILRMHITCLCLLKEALGERQSRVFEIALATEASTAIAGIFAPSKMSRAQFQMSPENHDSSTTISNDVGSNSSKVVVARATKIAAAVSALVVGAVIYGVTSLERMVTVLRLKEGLDVVQFARSTRSNSNGNARSIGAVKVDSSIEVYLHWFRLLVGNCRTICEGLVVELLGEPSIVALSRMQHMLSLSLVFPPAYSIFAFVKWWPFILNTNVAVREDMNHLHQSLTISITDAIKHLPFRDVCFRDGQGLYDLMATDPCDTEFATVLEVNSSDMHLKSMAFVPLRSRLFLNAMIDCKMPQFSGPGEYKLKDMLVHVLDTLQPAKFHWQWVALRLLLNEQALSEKLETHDMSLAEAIQLSSPNLEKSAAASENENNFIEILLTRLLVRPDAAPLYSELVHLIGRSLEDSMLLQVKWFLGGLDVLFGRKTIRQRLHNIAESKELSVKTQFWEPWGWCSPCTDPTIIKGDRKKFDTASLEEGEVVEEGTDPKRCLKGSSEVLVSESTSSNQLKVTERALIELLLPCIDQSSDESRSSFANDLIKQLNFIEQQITAVTRGASKPVGSTPLGVEGQTNKVSSRKMLKVGSPGLARRATIATDSSPPSPAALRASISLRLQLLLRFLPILCTDREPSVRNMRHTLSSVILRLLGSRVVHEDVDISMHCSLMRRELKSSSEAASAAFVDYSAEDLFDRLLLVLHGLLSSYSPSWLRQKPNSKTTNEHARELAGFDREVLETMQNELDHMQLPDTIRWRIQAAMPILLPSARYSFSCQPPHVPIYAVSCLQPSTANLGFNSSSSTVPQRNLVPLPRIAANAPGKAKQQDNDVEVDPWTLLEDGAGSCPSASNAASIGSRDHVNIRAASWLKGAVRVRRTDLTYVGAVDDDS
Length2228
PositionKinase
OrganismLupinus angustifolius (Narrow-leaved blue lupine)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> genistoids sensu lato> core genistoids> Genisteae> Lupinus.
Aromaticity0.07
Grand average of hydropathy-0.213
Instability index49.19
Isoelectric point8.68
Molecular weight247463.24
Publications
PubMed=27557478

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24546
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.47|      27|     700|    1204|    1235|       2
---------------------------------------------------------------------------
 1204- 1235 (41.84/38.26)	PLG.VPLGVEDPDDffrhKMSGGRLpSRVGS.GM
 1905- 1933 (40.63/21.74)	PVGsTPLGVEGQTN....KVSSRKM.LKVGSpGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     149.94|      36|     648|     525|     560|       4
---------------------------------------------------------------------------
  488-  522 (46.52/33.60)	KVA.KALDESL.VLGDLRGA..YKFLFedFCDGTVSEGW
  525-  560 (64.43/50.27)	KVS.PCLRLSLKWFGTVSSSLVYSAFF..LCEWATCDSR
  563-  594 (38.99/26.59)	RTTpPC...DVKFTGRKDLSQVHIAVR..LLKMKMRD..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.22|      36|     644|      95|     144|       5
---------------------------------------------------------------------------
   95-  134 (49.26/40.08)	EGLEEAREISLTQVSNfNKTVVLNCKEAIrkrLRAI.NESR
  729-  765 (53.96/29.49)	EALEESRIVEGTQLDE.ALQIYLNERRLI...LRGVlSEHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     189.65|      64|     648|     410|     476|       6
---------------------------------------------------------------------------
  410-  476 (98.49/81.95)	YLiLAVPDTFVGLDCF...PLPSSVVSH..TINDG.NFVLKSIEAAGTIKNSTDDFghVVSSIHKNAEYLAKA
 1057- 1126 (91.16/63.78)	YL.MDITDDLISASKFliwLLPKVLSSPnsTIQSGrNVLLLPRNVENQVCDVGEAF..LISSLRRYENILVAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.44|      22|    1236|     289|     314|      11
---------------------------------------------------------------------------
  289-  314 (40.96/32.81)	MQHkndpLLSVSDGEDPS...LHF.RWW.YI
 1527- 1553 (32.49/16.35)	MQH....MLSLSLVFPPAysiFAFvKWWpFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.08|      47|      92|     146|     194|      19
---------------------------------------------------------------------------
  146-  194 (75.01/56.86)	VALSGSQIAKPGVFPELRPCGEDFRKRwIEGLSQPHKRLRSlADQVPNG
  241-  287 (82.07/51.73)	IQLSRSEVWTKDVINYLQTLLDDFVSK.STSHSTPHTRERS.AQMLYTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.66|      21|    1049|     924|     944|      20
---------------------------------------------------------------------------
  924-  944 (35.32/23.54)	KPRQKNVRKTQS..LAQLQASRI
 1974- 1996 (31.34/19.97)	EPSVRNMRHTLSsvILRLLGSRV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24546 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) CTSAVNNSAIGGPSSRDNGKSDSSLPANFPVNSRRQQPQLAPYKLK
2) DDDSWWVKKGMKSSEPLKVEQPPKSVKQVTKPRQKNVRKTQSLAQLQASRI
3) SEGSIRRPIWSHHSKIDPVEASPGLQESRRVKRQKLSEERSSFVQGHS
9
894
841
54
944
888










Molecular Recognition Features






MoRF SequenceStartStop




1) IRRPIWSHHSKI
2) LAPYKLK
3) SWWVKKG
845
48
897
856
54
903