<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24149

Description Uncharacterized protein
SequenceMQRYAGAGNSNSSGFSGGPASAGGRDSSRLDVSPYAPPNYPLNPRRQQQLAPYRLKCDREPLNNKLGPPDFYPQTPNCPEETLTKEYVQSGYKETVEGIEEAREIVLSHISYFCKPDIVGKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDSRRKWAEALAQPNKRLRLLSEHVPHGYRRKSLFDVLTRCNVPLLRATWFVKVTYLNQVRPTSSSISTGASDNQRSNQWTKDVVEYLQQLLDEFNLKEAHPSFKEQPSAGLISGATQVKLKHEAPSAGGDTEEPLVHFKWWYMVRLVQWHLTEELLVPSVLIEWLCYQLQERDSVEALELLLPIVLGLVETITLSQTYVRMFVEILVRRLSDASAVDNPKRSSISSVIAELLRYMVLAVPDTFVSLDCFPLPSFVAPDVYGRGALLKITGGGEMSSSKRRDVYRYLSCGYAVCSIQRRASDLATLASPNVHARGAAKVVQALDKALVTGNLTMAYSSLFNDLSDALMEERWIKEVSPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRTSPSQNVKFTGRRDLSQIHLAVSILKNKMTEMNKLSRSKSSSRIAMNNIGKGSSLNDASVAATKVGDSSGLRSNGKNEEEKKERKDIFESPGPLHDIIVCWLDQHEVSSAAGFKRVDVLIIELIRSGVFYPQAYVRQLIISGVTDKNGTLLDMERKRRHHRILKQLPGSSLFDILEEDVVAEEQQLHEVMSTYSSERRLVLSELSSGQSFDANNRGEYTSSSYLRIPSGTNHGGVPEQVEDVKVLVSSLLCFIYPHSAESEQNETKMNFQGSSTSTLTQVDTGEAKNGCEDCMRINGQKLDERTSPFFPLIQSDEEDVWWVRKGTELQESFKAEPALKSIKQTSRGRAKVVRKTQNLAQLATAKIEGSQGEASTSHLCESKLSCPHHKPSTDGDNGKDADHTRMTNLAEVGKSLKKLRLLERRSISVWLLKSVRQLVEGNETTACKASNSISSFSSQPDDKTVPKWRLGDEELMSILYILDTCCDLASAARFLVWLLAKIRGGMGTLGQVGRSAAHMKNRDNQVCQVGEAFVFSSLLRYENILLATDLLPEVLNASTNRNFVLGTARHPAPAAFPYTRYFLRKYRDVASVVRWEKIFRTTCDQRLLADLDNGRSIDGDFVSSSGVLGGEEIDDQVRQKLSGRGSRIIPNMKEIVQRQAEEIQRNLKEKKIPAAPKSPSFEKEDSFQIAHDTVLGLVECIRQNGGATPDGDPSAVASAVSAVVVNAGHVIAKHLDFAGGNYHGVASIGNSLSFVRHTLHIHINSLCLLKEALGDRFSRVFEVALAVEASSAVTAAFAPPKVQRNQFQPSSETHDAYGNHTNEPLSTSGKGFVGRAGKVAAAISALVVGAVVHGAVSLERMIAVLKVKDGLEIQQVLRGLRPSNNGASRSAVTFKMDNSIEVLVHWFRILLGNCRTVYDGLIADILGESYVLALSRLQQKLPLSVVFPPAYSIFAIVRWRQYILSREDMQVYQSIANAINDITRHQPFRDICFRNTHQLYDLLAADVGDSEFAAMLETHCSDKNVRQLFMPLRGRLFLNALVDCKTPAVIQVDGSEPGEAKENELKVLSERLVQSLDTLQPAKFHWQWVELRLLLDEQALAEKLDKAEKSKIPMPILMTLADGLRKLSPNSESFTLSESEKGFTEIILSRLVARPDAAPLYSEVVHLLGKLQESLVVDVKWILQGQDAVLGRKSTRQQLLTIATRRGVPIKAQVWKPWGWSSLLTDVMANRSAKRKLEAAPIEEGEVVDDPADAKRPSKSTPNNVDRSVEATRSNINKYVTEKAFAELMLPCIDRSSPEFRSIFAGELIKQMGTVSEHIKAISRNGAKHVGLVPSGNDVSSNKSSGRKGIRGGSPNIGRRVTVGNDPTPPSASALQAIVWLRLQFIIRLLQVILADRGMRHTLAPAILSLLAARIIYEDADSPLPPASLIASRREVDSLLEPPMDVLLDRPSESLFERLLCVFHALLGNCKPSWMKSKPVSKPTVRASRDIPAFDNEAAVALQSALDHMELPGAIRRRIQAAMPILPPARHPSIQCQPSQLSLAALSPLQSTPSTSGPQQKSTSHSWVPTNISSRSKAVLPPQDPEMEVDPWTLLEDGTSCPSTSSGSNSASGIAPDHSNLKACSWLKGAVRVRRAELTYIGSLDDDS
Length2208
PositionKinase
OrganismAegilops tauschii subsp. strangulata (Goatgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Aegilops.
Aromaticity0.06
Grand average of hydropathy-0.281
Instability index50.14
Isoelectric point8.66
Molecular weight244073.72
Publications
PubMed=25035499
PubMed=29158546

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24149
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     504.76|     164|     617|    1167|    1339|       1
---------------------------------------------------------------------------
 1167- 1339 (259.50/176.71)	LLADLDNGRSIDGDfVSSSGVLGGEEIDDQVRQKlsgRGSRIIP.NMKEIVQRQAEEIQRNLKEKK.....IPAAPK.SPSFEKEDSFQIAHD..TVLGLVECIRQNG....GATPDG.DPSAVASAVSAVVVNAGHVIAKHLDFAGGNYHGVASIGNSLSFVRHTLHIHinslcLLKEALGDRFSR
 1783- 1960 (245.26/146.74)	LLTDVMANRSAKRK.LEAAPIEEGEVVDDPADAK...RPSKSTPnNVDRSVEATRSNINKYVTEKAfaelmLPCIDRsSPEFRSIFAGELIKQmgTVSEHIKAISRNGakhvGLVPSGnDVSSNKSSGRKGIRGGSPNIGRRVTVGNDPTPPSASALQAIVWLRLQFIIR.....LLQVILADRGMR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.36|      14|      49|     421|     434|       2
---------------------------------------------------------------------------
  421-  434 (26.54/18.00)	LPSFVAPDVYGRGA
  472-  485 (22.81/14.22)	LATLASPNVHARGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.49|      20|     617|     377|     396|       3
---------------------------------------------------------------------------
  377-  396 (33.70/21.74)	VRRLSDASAVDNPKRS.SISS
  995- 1015 (29.79/18.25)	VRQLVEGNETTACKASnSISS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.75|      21|      23|     309|     331|       4
---------------------------------------------------------------------------
  301-  321 (41.85/26.18)	TEEPLVH..FKWWYMVRLVQWHL
  322-  344 (33.90/26.08)	TEELLVPsvLIEWLCYQLQERDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.54|      15|      18|    1969|    1986|       5
---------------------------------------------------------------------------
 1969- 1986 (22.52/21.03)	SLLAARiiyEDADSPLPP
 1988- 2002 (26.01/14.55)	SLIASR...REVDSLLEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.09|      31|      51|    2085|    2116|       6
---------------------------------------------------------------------------
 2085- 2116 (51.77/32.96)	ILPPaRHPSIQCQP.SQLSLAALSPLQSTPSTS
 2139- 2170 (52.32/29.17)	VLPP.QDPEMEVDPwTLLEDGTSCPSTSSGSNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.36|      15|      23|    1485|    1505|       7
---------------------------------------------------------------------------
 1485- 1499 (24.04/20.48)	ILGESY.VLALSRLQQ
 1506- 1521 (24.32/ 6.96)	VFPPAYsIFAIVRWRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.29|      15|      23|     895|     910|       8
---------------------------------------------------------------------------
  895-  910 (20.81/17.15)	AEPALKSIkQTSRGRA
  920-  934 (24.49/14.98)	AQLATAKI.EGSQGEA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24149 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAPIEEGEVVDDPADAKRPSKSTPNNVDRSVEATR
2) ALSPLQSTPSTSGPQQKSTSHSWVPTNISSRSKAVLPPQDPEMEVDPWTLLEDGTSCPSTSSGSNSASGIA
3) HLCESKLSCPHHKPSTDGDNGKDADHTRMT
4) LVPSGNDVSSNKSSGRKGIRGGSPNIGRRVTVGND
5) MQRYAGAGNSNSSGFSGGPASAGGRDSSRLDVSPYAPPNYPLNPRRQQQLAPYRLKCDR
1799
2105
938
1892
1
1833
2175
967
1926
59










Molecular Recognition Features






MoRF SequenceStartStop




NANANA