<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24142

Description Uncharacterized protein
SequenceREAREIVLSHISYFCKPDIVGKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDSRRKWAEALAQPNKRLRLLSEHVPHGYRRKSLFDVLTRCNVPLLRATWFVKVTYLNQVRPTSSSISTGASDNQRSNQWTKDVVEYLQQLLDEFNLKEAHPSFKEQPSAGLISGATQVKLKHEAPSAGGDTEEPLVHFKWWYMVRLVQWHLTEELLVPSVLIEWLCYQLQERDSVEALELLLPIVLGLVETITLSQTYVRMFVEILVRRLSDASAVDNPKRSSISSVIAELLRYMVLAVPDTFVSLDCFPLPSFVAPDVYGRGALLKITGGGEMSSSKRRDVYRYLSCGYAVCSIQRRASDLATLASPNVHARGAAKVVQALDKALVTGNLTMAYSSLFNDLSDALMEERWIKEVSPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRTSPSQNVKFTGRRDLSQIHLAVSILKNKMTEMNKLSRSKSSSRIAMNNIGKGSSLNDASVAATKVGDSSGLRSNGKNEEEKKERKDIFESPGPLHDIIVCWLDQHEVSSAAGFKRVDVLIIELIRSGVFYPQAYVRQLIISGVTDKNGTLLDMERKRRHHRILKQLPGSSLFDILEEDVVAEEQQLHEVMSTYSSERRLVLSELSSGQSFDANNRGEYTSSSYLRIPSGTNHGGVPEQVEDVKVLVSSLLCFIYPHSAESEQNETKMNFQGSSTSTLTQVDTGEAKNGCEDCMRINGQKLDERTSPFFPLIQSDEEDVWWVRKGTELQESFKAEPALKSIKQTSRGRAKVVRKTQNLAQLATAKIEGSQGEASTSHLCESKLSCPHHKPSTDGDNGKDADHTRMTNLAEVGKSLKKLRLLERRSISVWLLKSVRQLVEGNETTACKASNSISSFSSQPDDKTVPKWRLGDEELMSILYILDTCCDLASAARFLVWLLAKIRGGMGTLGQVGRSAAHMKNRDNQVCQVGEAFVFSSLLRYENILLATDLLPEVLNASTNRNFVLGTARHPAPAAFPYTRYFLRKYRDVASVVRWEKIFRTTCDQRLLADLDNGRSIDGDFVSSSGVLGGEEIDDQVRQKLSGRGSRIIPNMKEIVQRQAEEIQRNLKEKKIPAAPKSPSFEKEDSFQIAHDTVLGLVECIRQNGGATPDGDPSAVASAVSAVVVNAGHVIAKHLDFAGGNYHGVASIGNSLSFVRHTLHIHINSLCLLKEALGDRFSRVFEVALAVEASSAVTAAFAPPKVQRNQFQPSSETHDAYGNHTNEPLSTSGKGFVGRAGKVAAAISALVVGAVVHGAVSLERMIAVLKVKDGLEIQQVLRGLRPSNNGASRSAVTFKMDNSIEVLVHWFRILLGNCRTVYDGLIADILGESYVLALSRLQQKLPLSVVFPPAYSIFAIVRWRQYILSREDMQVYQSIANAINDITRHQPFRDICFRNTHQLYDLLAADVGDSEFAAMLETHCSDKNVRQLFMPLRGRLFLNALVDCKTPAVIQVDGSEPGEAKENELKVLSERLVQSLDTLQPAKFHWQWVELRLLLDEQALAEKLDKAEKSKIPMPILMTLADGLRKLSPNSESFTLSESEKGFTEIILSRLVARPDAAPLYSEVVHLLGKLQESLVVDVKWILQGQDAVLGRKSTRQQLLTIATRRGVPIKAQVWKPWGWSSLLTDVMANRSAKRKLEAAPIEEGEVVDDPADAKRPSKSTPNNVDRSVEATRSNINKYVTEKAFAELMLPCIDRSSPEFRSIFAGELIKQMGTVSEHIKAISRNGAKHVGLVPSGNDVSSNKSSGRKGIRGGSPNIGRRVTVGNDPTPPSASALQAIVWLRLQFIIRLLQVILADRGMRHTLAPAILSLLAARIIYEDADSPLPPASLIASRREVDSLLEPPMDVLLDRPSESLFERLLCVFHALLGNCKPSWMKSKPVSKPTVRASRDIPAFDNEAAVALQSALDHMELPGAIRRRIQAAMPILPPARHPSIQCQPSQLSLAALSPLQSTPSTSGPQQKSTSHSWVPTNISSRSKAVLPPQDPEMEVDPWTLLEDGTSCPSTSSGSNSASGIAPDHSNLKACSWLKGAVRVRRAELTYIGSLDDDS
Length2109
PositionKinase
OrganismAegilops tauschii subsp. strangulata (Goatgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Aegilops.
Aromaticity0.06
Grand average of hydropathy-0.246
Instability index49.11
Isoelectric point8.72
Molecular weight233267.99
Publications
PubMed=25035499
PubMed=29158546

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24142
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.36|      14|      49|     322|     335|       1
---------------------------------------------------------------------------
  322-  335 (26.54/16.98)	LPSFVAPDVYGRGA
  373-  386 (22.81/13.39)	LATLASPNVHARGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.09|      31|      51|    1986|    2017|       2
---------------------------------------------------------------------------
 1986- 2017 (51.77/39.79)	ILPPaRHPSIQCQP.SQLSLAALSPLQSTPSTS
 2040- 2071 (52.32/35.25)	VLPP.QDPEMEVDPwTLLEDGTSCPSTSSGSNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.82|      24|      25|    1414|    1437|       3
---------------------------------------------------------------------------
 1361- 1384 (33.61/28.92)	IEVLVHWFRI..LLG.NCRTVYDGlIA
 1414- 1437 (41.34/38.06)	IFAIVRWRQY..ILSREDMQVYQS.IA
 1440- 1465 (35.87/31.60)	INDITRHQPFrdICFRNTHQLYDL.LA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.75|      21|      23|     210|     232|       4
---------------------------------------------------------------------------
  202-  222 (41.85/27.56)	TEEPLVH..FKWWYMVRLVQWHL
  223-  245 (33.90/27.45)	TEELLVPsvLIEWLCYQLQERDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.69|      26|      47|    1613|    1640|       5
---------------------------------------------------------------------------
 1613- 1640 (38.16/30.88)	VARPDAAPLYSEVVHLLGklQESLVVDV
 1663- 1688 (48.53/33.01)	IATRRGVPIKAQVWKPWG..WSSLLTDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.29|      15|      23|     796|     811|       6
---------------------------------------------------------------------------
  796-  811 (20.81/16.78)	AEPALKSIkQTSRGRA
  821-  835 (24.49/14.66)	AQLATAKI.EGSQGEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.34|      15|      18|    1870|    1887|       9
---------------------------------------------------------------------------
 1870- 1887 (22.40/24.48)	SLLAARiiyEDADSPLPP
 1889- 1903 (25.94/16.94)	SLIASR...REVDSLLEP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.44|      23|      47|     875|     899|      10
---------------------------------------------------------------------------
  875-  897 (38.28/24.83)	KSLKKLRLLERRSIS..................VWLLKSVR
  924-  964 (31.16/13.06)	KTVPKWRLGDEELMSilyildtccdlasaarflVWLLAKIR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.11|      10|      23|     471|     480|      15
---------------------------------------------------------------------------
  471-  480 (17.61/ 9.43)	KFTGRRDLSQ
  491-  500 (17.50/ 9.32)	KMTEMNKLSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.96|      10|      19|     342|     351|      17
---------------------------------------------------------------------------
  342-  351 (17.95/ 9.39)	GGEMSSSKRR
  360-  369 (19.01/10.37)	GYAVCSIQRR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24142 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAPIEEGEVVDDPADAKRPSKSTPNNVDRSVEATR
2) ALSPLQSTPSTSGPQQKSTSHSWVPTNISSRSKAVLPPQDPEMEVDPWTLLEDGTSCPSTSSGSNSASGIA
3) HLCESKLSCPHHKPSTDGDNGKDADHTRMT
4) LVPSGNDVSSNKSSGRKGIRGGSPNIGRRVTVGND
1700
2006
839
1793
1734
2076
868
1827










Molecular Recognition Features






MoRF SequenceStartStop




NANANA