<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24138

Description Uncharacterized protein
SequenceMQRYAGAGNSNSSGFSGGPASAGGRDSSRLDVSPYAPPNYPLNPRRQQQLAPYRLKCDREPLNNKLGPPDFYPQTPNCPEETLTKEYVQSGYKETVEGIEEAREIVLSHISYFCKPDIVGKCKEALKKRLRAINESRAQKRKAGQVYGVPLSGSLLIKPGVYPEQRPCNEDSRRKWAEALAQPNKRLRLLSEHVPHGYRRKSLFDVLTRCNVPLLRATWFVKVTYLNQVRPTSSSISTGASDNQRSNQWTKDVVEYLQQLLDEFNLKEAHPSFKEQPSAGLISGATQVKLKHEAPSAGGDTEEPLVHFKWWYMVRLVQWHLTEELLVPSVLIEWLCYQLQERDSVEALELLLPIVLGLVETITLSQTYVRMFVEILVRRLSDASAVDNPKRSSISSVIAELLRYMVLAVPDTFVSLDCFPLPSFVAPDVYGRGALLKITGGGEMSSSKRRDVYRYLSCGYAVCSIQRRASDLATLASPNVHARGAAKVVQALDKALVTGNLTMAYSSLFNDLSDALMEERWIKEVSPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRTSPSQNVKFTGRRDLSQIHLAVSILKNKMTEMNKLSRSKSSSRIAMNNIGKGSSLNDASVAATKVGDSSGLRSNGKNEEEKKERKDIFESPGPLHDIIVCWLDQHEVSSAAGFKRVDVLIIELIRSGVFYPQAYVRQLIISGVTDKNGTLLDMERKRRHHRILKQLPGSSLFDILEEDVVAEEQQLHEVMSTYSSERRLVLSELSSGQSFDANNRGEYTSSSYLRIPSGTNHGGVPEQVEDVKVLVSSLLCFIYPHSAESEQNETKMNFQGSSTSTLTQVDTGEAKNGCEDCMRINGQKLDERTSPFFPLIQSDEEDVWWVRKGTELQESFKAEPALKSIKQTSRGRAKVVRKTQNLAQLATAKIEGSQGEASTSHLCESKLSCPHHKPSTDGDNGKDADHTRMTNLAEVGKSLKKLRLLERRSISVWLLKSVRQLVEGNETTACKASNSISSFSSQPDDKTVPKWRLGDEELMSILYILDTCCDLASAARFLVWLLAKIRGGMGTLGQVGRSAAHMKNRDNQVCQVREHTSCN
Length1096
PositionKinase
OrganismAegilops tauschii subsp. strangulata (Goatgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Aegilops.
Aromaticity0.07
Grand average of hydropathy-0.411
Instability index50.90
Isoelectric point8.55
Molecular weight122355.78
Publications
PubMed=25035499
PubMed=29158546

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24138
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     282.36|      69|     388|     230|     299|       1
---------------------------------------------------------------------------
  230-  299 (113.00/63.48)	RPTSSS......ISTGASDNQRSNQWTK..DVVEYLQQLL............DEFNLKE.AHPSFKEQPSaGLISGATQVKL.KHEAPSAGG
  506-  580 (79.56/40.31)	....SS......LFNDLSDALMEERWIK..EVSPCLQSSLmwigtvelslicSIFFLCEwATCDYRDCRT....SPSQNVKF.TGRRDLSQI
  599-  674 (89.81/46.35)	RSKSSSriamnnIGKGSSLNDASVAATKvgDSSGLRSNGK............NEEEKKE.RKDIF.ESP..GPLHDIIVCWLdQHEVSSAAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     143.04|      52|     617|     377|     470|       2
---------------------------------------------------------------------------
  377-  449 (81.69/104.09)	VRRLSDASAVDNPKRS.SISS........viaellrymvlavpdtfvsldCFPLPSFVAPDVYGRGALLKITGG.GEMSSSKR
  472-  485 ( 0.95/12.18)	.....................................................LATLASPNVHARGA................
  995- 1074 (60.40/25.94)	VRQLVEGNETTACKASnSISSfssqpddktvpkwrlgdeelmsilyildtCCDLASAARFLVW...LLAKIRGGmGTLGQVGR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     226.71|      70|     653|      80|     163|       3
---------------------------------------------------------------------------
   80-  150 (110.20/66.43)	EETLTKEYVQSGYKETVEGIE..EAREIVLSHISYFCKPDIVGKCKEALKKRLRaINESRAQKRKAGQVYGVP
  738-  805 (108.03/60.83)	EEDVVAEEQQ..LHEVMSTYS..SERRLVLSELSSGQSFDANNRGEYTSSSYLR.IPSGTNHGGVPEQVEDVK
  823-  848 ( 8.47/ 8.76)	EQNETKMNFQGSSTSTLTQVDtgEAK...............................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.51|      22|      22|     310|     331|       6
---------------------------------------------------------------------------
  310-  331 (43.62/30.98)	WWYMVRLVQWHLTE..ELLVPSVL
  333-  356 (34.89/23.20)	EWLCYQLQERDSVEalELLLPIVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      83.74|      24|     485|     187|     211|       7
---------------------------------------------------------------------------
  187-  211 (40.50/32.18)	LRLLsEHVPHGYRRKSLFDVLTRCN
  693-  709 (20.57/ 9.60)	........PQAYVRQLIISGVTDKN
  722-  737 (22.67/11.73)	HRIL.KQLP.G...SSLFDIL....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.17|      14|      17|      31|      45|       9
---------------------------------------------------------------------------
   31-   44 (29.40/20.24)	DVSPY......APPNYPLNP
   49-   68 (20.78/ 6.87)	QLAPYrlkcdrEPLNNKLGP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24138 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) HLCESKLSCPHHKPSTDGDNGKDADHTRMT
2) MQRYAGAGNSNSSGFSGGPASAGGRDSSRLDVSPYAPPNYPLNPRRQQQLAPYRLKCDR
938
1
967
59










Molecular Recognition Features






MoRF SequenceStartStop




NANANA