<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24137

Description Uncharacterized protein
SequenceINSQRQQQLAPYRLKCDREPLNNKLGPPDFYPQTPNCPEETLTKEYVQSGYKETVEGIEEAREIVLSHISYFCKPDIVGKCKEALKKRLRAINESRAQKRKALAQPNKRLRLLSEHVPHGYRRKSLFDVLTRCNVPLLRATWFVKVTYLNQPQVRPTSSSISTGASDNQRSNQWTKDVVEYLQQLLDEFNLKEAHPSFKEQPSAGLISGATQVKLKHEAPSAGGDTEEPLVHFKWWYMVRLVQWHLTEELLVPSVLIEWLCYQLQERDSVEALELLLPIVLGLVETITLSQTYVRMFVEILVRRLSDASAVDNPKRSSISSVIAELLRYMVLAVPDTFVSLDCFPLPSFVAPDVYGRGALLKITGGGEMSSSKRRDVYRYLSCGYAVCSIQRRASDLATLASPNVHARGAAKVVQALDKALVTGNLTMAYSSLFNDLSDALMEERWIKEVSPCLQSSLMWIGTVELSLICSIFFLCEWATCDYRDCRTSPSQNVKFTGRRDLSQIHLAVSILKNKMTEMNKLSRSKSSSRIAMNNIGKGSSLNDASVAATKVGDSSGLRSNGKNEEEKKERKDIFESPGPLHDIIVCWLDQHEVSSAAGFKRVDVLIIELIRSGVFYPQAYVRQLIISGVTDKNGTLLDMERKRRHHRILKQLPGSSLFDILEEDVVAEEQQLHEVMSTYSSERRLVLSELSSGQSFDANNRGEYTSSSYLRIPSGTNHGGVPEQVEDVKVLVSSLLCFIYPHSAESEQNETKMNFQGSSTSTLTQVDTGEAKNGCEDCMRINGQKLDERTSPFFPLIQSDEEDVWWVRKGTELQESFKAEPALKSIKQTSRGRAKVVRKTQNLAQLATAKIEGSQGEASTSHLCESKLSCPHHKPSTDGDNGKDADHTRMTNLAEVGKSLKKLRLLERRSISVWLLKSPDDKTVPKWRLGDEELMSILYILDTCCDLASAARFLVWLLAKIRGGMGTLGQVGRSAAHMKNRDNQVCQVGEAFVFSSLLRYENILLATDLLPEVLNASTNRNFVLGTARHPAPAAFPYTRYFLRKYRDVASVVRWEKIFRTTCDQRLLADLDNGRSIDGDFVSSSGVLGGEEIDDQVRQKLSGRGSRIIPNMKEIVQRQAEEIQRNLKEKKIPAAPKSPSFEKEDSFQIAHDTVLGLVECIRQNGGATPDGDPSAVASAVSAVVVNAGHVIAKHLDFLKEALGDRFSRVFEVALAVEASSAVTAAFAPPKVQRNQFQPSSETHDAYGNHTNEPLSTSGKGFVGRAGKVAAAISALVVGAVVHGAVSLERMIAVLKVKDGLEIQQVLRGLRPSNNGASRSAVTFKMDNSIEVLVHWFRILLGNCRTVYDGLIADILGESYVLALSRLQQKLPLSVVFPPAYSIFAIVRWRQYILSREDMQVYQSIANAINDITRHQPFRDICFRNTHQLYDLLAADVGDSEFAAMLETHCSDKNVRQLFMPLRGRLFLNALVDCKTPAVIQVDGSEPGEAKENELKVLSERLVQSLDTLQPAKFHWQWVELRLLLDEQALAEKLDKAEKSKIPMPILMTLADGLRKLSPNSESFTLSESEKGFTEIILSRLVARPDAAPLYSEVVHLLGKLQESLVVDVKWILQGQDAVLGRKSTRQQLLTIATRRGVPIKAQVWKPWGWSSLLTDVMANRSAKRKLEAAPIEEGEVVDDPADAKRPSKSTPNNVDRSVEATRSNINKYVTEKAFAELMLPCIDRSSPEFRSIFAGELIKQMGTVSEHIKAISRNGAKHVGLVPSGNDVSSNKSSGRKGIRGGSPNIGRRVTVGNDPTPPSASALQAIVWLRLQFIIRLLQVILADRGMRHTLAPAILSLLAARIIYEDADSPLPPASLIASRREVDSLLEPPMDVLLDRPSESLFERLLCVFHALLGNCKPSWMKSKPVSKPTVRASRDIPAFDNEAAVALQSALDHMELPGAIRRRIQAAMPILPPARHPSIQCQPSQLSLAALSPLQSTPSTSGPQQKSTSHSWVPTNISSRSKAVLPPQDPEMEVDPWTLLEDGTSCPSTSSGSNSASGIAPDHSNLKACSWLKGAVRVRRAELTYIGSLDDDS
Length2077
PositionKinase
OrganismAegilops tauschii subsp. strangulata (Goatgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Aegilops.
Aromaticity0.06
Grand average of hydropathy-0.273
Instability index49.93
Isoelectric point8.57
Molecular weight230294.61
Publications
PubMed=25035499
PubMed=29158546

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24137
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.87|      18|      20|      84|     103|       1
---------------------------------------------------------------------------
   86-  103 (29.47/17.33)	KKRLRAINE..SRAQKRKAL
  107-  126 (27.40/ 9.98)	NKRLRLLSEhvPHGYRRKSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.59|      13|      19|    1834|    1851|       2
---------------------------------------------------------------------------
 1834- 1851 (13.18/23.30)	PAilSLLAARiiyEDADS
 1855- 1867 (23.41/14.68)	PA..SLIASR...REVDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.36|      14|      49|     346|     359|       3
---------------------------------------------------------------------------
  346-  359 (26.54/15.39)	LPSFVAPDVYGRGA
  397-  410 (22.81/12.12)	LATLASPNVHARGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.91|      17|      19|      39|      57|       4
---------------------------------------------------------------------------
   39-   57 (25.07/22.43)	EETltKEYVQS..GY..KETVEG
   59-   79 (18.84/ 9.25)	EEA..REIVLShiSYfcKPDIVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.61|      28|     108|     958|     988|       5
---------------------------------------------------------------------------
  819-  846 (41.99/21.55)	KAEPALKSIKQTSRGRAKVVRKTQNLAQ
  961-  988 (48.62/34.75)	KIRGGMGTLGQVGRSAAHMKNRDNQVCQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     325.20|      93|     583|    1067|    1172|       6
---------------------------------------------------------------------------
  688-  784 (111.68/73.24)	.LSELSSGQSFDannrGEYTSSSylRIPSGtnhggvpEQVE...D.VKVLVSSLLCFIYPHSAESEQ...............N..ETKMNFQGSSTStLTQVDTGE.AKN...GCEDCMRING
 1067- 1165 (142.60/132.46)	LLADLDNGRSID....GDFVSSS..GVLGG.......EEID...DQVRQKLSGRGSRIIPNMKEIVQRQA.......EEIQRNlkEKKIPAAPKSPS.FEKEDSFQiAHDtvlGLVECIRQNG
 1175- 1246 (70.92/43.10)	AVASA..............VSAV..VVNAG.......HVIAkhlDFLKEALGDRFSRVFEVALAVEASSAvtaafapPKVQRN.........QFQPS.SETHDAY..................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.69|      26|      47|    1581|    1608|       7
---------------------------------------------------------------------------
 1581- 1608 (38.16/34.49)	VARPDAAPLYSEVVHLLGklQESLVVDV
 1631- 1656 (48.53/36.84)	IATRRGVPIKAQVWKPWG..WSSLLTDV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.75|      21|      23|     234|     256|       8
---------------------------------------------------------------------------
  226-  246 (41.85/27.93)	TEEPLVH..FKWWYMVRLVQWHL
  247-  269 (33.90/27.82)	TEELLVPsvLIEWLCYQLQERDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.98|      15|     584|    1330|    1344|       9
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 1330- 1344 (30.46/18.01)	EVLVHWFRILLGNCR
 1886- 1900 (29.52/17.24)	ERLLCVFHALLGNCK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     104.09|      31|      51|    1954|    1985|      10
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 1954- 1985 (51.77/33.46)	ILPPaRHPSIQCQP.SQLSLAALSPLQSTPSTS
 2008- 2039 (52.32/29.63)	VLPP.QDPEMEVDPwTLLEDGTSCPSTSSGSNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.30|      18|      18|    1006|    1023|      12
---------------------------------------------------------------------------
 1006- 1023 (29.47/17.42)	LATDLLPEVLNASTNRNF
 1025- 1042 (33.84/21.17)	LGTARHPAPAAFPYTRYF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.36|      15|      19|    1354|    1368|      13
---------------------------------------------------------------------------
 1354- 1368 (24.04/15.70)	ILGESY.VLALSRLQQ
 1375- 1390 (24.32/15.99)	VFPPAYsIFAIVRWRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.51|      20|      23|     903|     922|      14
---------------------------------------------------------------------------
  903-  922 (33.87/20.66)	KLRLLERRSISV.WLLKSPDD
  927-  947 (33.64/20.47)	KWRLGDEELMSIlYILDTCCD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.96|      10|      18|     366|     375|      18
---------------------------------------------------------------------------
  366-  375 (17.95/10.12)	GGEMSSSKRR
  384-  393 (19.01/11.18)	GYAVCSIQRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.11|      10|      18|     495|     504|      19
---------------------------------------------------------------------------
  495-  504 (17.61/12.37)	KFTGRRDLSQ
  515-  524 (17.50/12.23)	KMTEMNKLSR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.19|      20|      23|    1478|    1497|      20
---------------------------------------------------------------------------
 1478- 1497 (32.15/22.75)	VIQVDGSEPGEAKEN..ELKVL
 1502- 1523 (30.04/20.66)	VQSLDTLQPAKFHWQwvELRLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24137 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAPIEEGEVVDDPADAKRPSKSTPNNVDRSVEATR
2) ALSPLQSTPSTSGPQQKSTSHSWVPTNISSRSKAVLPPQDPEMEVDPWTLLEDGTSCPSTSSGSNSASGIA
3) LVPSGNDVSSNKSSGRKGIRGGSPNIGRRVTVGND
1668
1974
1761
1702
2044
1795










Molecular Recognition Features






MoRF SequenceStartStop




NANANA