Description | Mediator of RNA polymerase II transcription subunit 10 |
Sequence | NLAQVTGSIQKTLGLLHQLNLNVSSFSSASQLPLLQRLNALVAELDTMQKLADGCNIQVPMEVVNLIDDGKNPDEFTRDVLNSCIAKNQITKGKTDAFKRA |
Length | 101 |
Position | Middle |
Organism | Aegilops tauschii subsp. strangulata (Goatgrass) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Aegilops. |
Aromaticity | 0.03 |
Grand average of hydropathy | -0.145 |
Instability index | 19.84 |
Isoelectric point | 6.76 |
Molecular weight | 10994.49 |
Publications | PubMed=25035499 PubMed=29158546 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP24107 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 44.31| 13| 16| 8| 23| 1 --------------------------------------------------------------------------- 8- 20 (22.36/17.48) SIQKTLGLLHQLN 27- 39 (21.95/ 8.50) SSASQLPLLQRLN --------------------------------------------------------------------------- --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 43.84| 13| 20| 65| 78| 2 --------------------------------------------------------------------------- 65- 78 (20.00/16.16) NLIDDGKNpDEFTR 88- 100 (23.84/13.69) NQITKGKT.DAFKR --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) LAQVTGSIQKTLG 2) LPLLQRLNA 3) PDEFTRDVLNSCIAKNQITKGKTDAFKRA 4) PMEVVNLI | 2 32 73 60 | 14 40 101 67 |
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