<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP24030

Description ATP-dependent DNA helicase
SequenceMPKTKKCLEDIDCFIRENHPKECGIIYCLSRMDCEKVAEKLREYGHQASHYHGNMEPSDRAAVQRLWSMDKINIICATVAFGMGINKPDVRFVIHHSLPKSIEGYHQECGRAGRDGQRSSCVLYYNYSDYIRVKHMITQGSAEQVRSSSSSSHGQALATHKENLLCMVSYCENDVDCRRLLQLIHFGETFDPSHCSKTCDNCKKGLRWIEKDVTNIAKQLVELVLTTRQSCSSSHILEVYRGSLNQNVKKNHHDILPLHGAGKNLAKGEAARVLRHLVTEGILTEDVKKSDTYGSVSSVLKANQVKVGGLRSGKQIVLKFPTADKAPKMGKLDESSISQVNKTVQRQSEMDENFSSLLYETLRILRSQIAEGTAGCGVHHIFKNETLKEISTRIPRTKEELLEINGIGKVKLNKYGDRVLATIEEFLNQFPNGSKRSSSSGGSNEQNEAVKKRRGFPAIHTSGNGNDFEERTVQSKKHTGKTRNGKQGIPDAASVIQDVRYIDVDLDGCEEVDELCSSVQQPLASGRVLPKWTAGGNATTPNIFEEFKYTN
Length551
PositionUnknown
OrganismAegilops tauschii subsp. strangulata (Goatgrass)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Poales> Poaceae> BOP clade> Pooideae> Triticodae> Triticeae> Triticinae> Aegilops.
Aromaticity0.06
Grand average of hydropathy-0.579
Instability index47.57
Isoelectric point8.71
Molecular weight61517.04
Publications
PubMed=25035499
PubMed=29158546

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
3'-5' DNA helicase activity	GO:0043138	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
nucleic acid binding	GO:0003676	IEA:InterPro

GO - Biological Process
DNA recombination	GO:0006310	IEA:InterPro
DNA repair	GO:0006281	IEA:InterPro
DNA replication	GO:0006260	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP24030
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      72.38|      16|      22|     169|     184|       1
---------------------------------------------------------------------------
   26-   36 (15.64/ 6.48)	IYCLSRMD.CEK.....
  169-  184 (29.52/19.05)	SYCENDVD.CRRLLQLI
  193-  209 (27.21/16.96)	SHCSKTCDnCKKGLRWI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.77|      17|     139|     132|     148|       2
---------------------------------------------------------------------------
  132-  148 (30.32/23.18)	RV.KHMITQG.SAEQVRSS
  272-  290 (20.46/13.19)	RVlRHLVTEGiLTEDVKKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.83|      23|      24|     383|     406|       3
---------------------------------------------------------------------------
  383-  406 (33.88/27.21)	KNEtLKEISTRIPRTKEELLE..ING
  409-  433 (34.94/22.95)	KVK.LNKYGDRVLATIEEFLNqfPNG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.88|      14|      16|     235|     250|       4
---------------------------------------------------------------------------
  235-  250 (16.26/18.54)	H..ILEVYrGSlNQNVKK
  252-  267 (20.62/11.61)	HhdILPLH.GA.GKNLAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.65|      16|      20|     439|     454|       6
---------------------------------------------------------------------------
  439-  454 (25.37/18.62)	SSGGSNEQNEAVKKRR
  462-  477 (26.28/19.58)	SGNGNDFEERTVQSKK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP24030 with Med34 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PNGSKRSSSSGGSNEQNEAVKKRRGFPAIHTSGNGNDFEERTVQSKKHTGKTRNGKQGIP
431
490










Molecular Recognition Features






MoRF SequenceStartStop




1) AVKKRRGFPAIHT
2) PNIFEEFKYTN
449
541
461
551