<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23857

Description Mediator complex subunit 24
SequenceMKVVNLKQAILQAWKERWSDYQWAINMKKFFPKGATWDILNLAEALLEQAMIGPSPNPLILSYLKYAISSQMVSYSTVLMAISKFDDFSRDLCVQSLLEIMDMFCDRLSCHGKAEECIGLCRALMSALNWMLRCAAFYTEKFKDVLDQVAAENQLKMCLERLEKILGSTKNRALIHIGKLEETSSWSAIEQSLIKLGENLSVLSNPQLRSQADECISLIKSIPTMLSAHSEQLNKTGFPTVHAVVLLEGTMNLTGETQPLVEQLMMVKRMQRIPSPLFVLEIWKACFVGLIESPEGTEELKWTAFTFLKIPQVLVKLKKYPQGEKDFTEDVNCAFEFLLKLTPLLDKADQRCNCDCTSLLLQECSKQGLLSEAHMTNLVAKRTADREHAPRLKSAENANIQPNPGLILRAEPTVTNILKTMDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFTKHISGEGSKAASVRALLFDISFLMLCHVAQTYGSEVILSESSPTGEVPFFETWMQTCMPEEGKILNPDHPCFRPDSTKVESLVALLNSSSEMKLVQMKWHEACLSISAAILEILNAWENGVLTFESIQKITDNIKGKVCSMAVCTMAWLVAHVRMLGLDERDKSLQMIRQLATSLQSENTLQFYNERVVIMSSILERMCADVLQQTATQIRFPSTGTDPIPYWNLLPPKKPIKEVLMGVFTKVLEKGWVDSRSIHIFDTLLHMGGVYWFCNNLVKELLKETRKEHTLRAVELLYAIFCLDMQQLTLSLLGHILPSLLTDSSKWHTLMDPPGKALAKLSVWCALSSYSSHNKGQASARQKKRHREDIEDYISLFPLDDTQPSKLMRLLSSNEEDPNVLSSPTDRSMSSSLSASQLHTVSMRDPLNRVLANLFLLISSILGAKTAGTHTQFVQWFMEECVDCLEQGSRGSILQFMPFTMVSELVKVSTMSSPKIVLAITDLSLPLGRRVAAKAIAAL
Length987
PositionTail
OrganismGopherus agassizii (Agassiz's desert tortoise)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Testudines> Cryptodira> Durocryptodira> Testudinoidea> Testudinidae> Gopherus.
Aromaticity0.07
Grand average of hydropathy-0.000
Instability index48.54
Isoelectric point6.89
Molecular weight110488.77
Publications
PubMed=28562605

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:Ensembl

GO - Biological Function
GO - Biological Process
stem cell population maintenance	GO:0019827	IEA:Ensembl
transcription by RNA polymerase II	GO:0006366	IEA:Ensembl









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23857
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     266.98|      83|     158|     253|     339|       1
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  253-  296 (55.72/29.79)	...........................................................................LTGETQPLVEQLMMVKRMQR..............IPSPLFVL.......EIW.KACF..VGLIESPEG
  297-  431 (97.08/68.42)	TEELKWTAFTFLKipqvLVKLKKYPQGEKDFTEDVNC...AFEFLLkltplldkadqrcncdctslllqecskqgLLSEAH..MTNLVAKRTADRehaprlksaenaniQPNPGLILraeptvtNIL.KTMD..ADHSKSPEG
  455-  540 (114.18/71.11)	TGKLKSFARKFIK....LNEFTKHISGEGSKAASVRAllfDISFLM.............................LCHVAQTYGSEVILSESSPT..............GEVPFF.........ETWmQTCMpeEGKILNPD.
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     359.20|     117|     158|     684|     807|       2
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  684-  807 (186.37/148.42)	FPSTGTDPIPYWNLLPPKKPIKEVLMGVFTKVLEKGWVDSR..SIHIFDTLLH.MGGVYWfcnnLVKELL.KETRKEHTlRAVELLYAiFCLD.MQQLTLSLLGHILP.SLLTDSSKWHTlMDPPGKALA
  845-  967 (172.84/115.26)	FPLDDTQPSKLMRLLSSNEEDPNVLSSPTDRSMSSSLSASQlhTVSMRDPLNRvLANLFL....LISSILgAKTAGTHT.QFVQWFME.ECVDcLEQGSRGSILQFMPfTMVSELVKVST.MSSPKIVLA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     147.17|      48|      95|      79|     128|       3
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   79-  127 (82.34/53.34)	LMAISKFDDFSRDLCV.QSLLEIMDMFcDRLS...CHGKAEECIGLCRA...LMSA
  174-  228 (64.83/32.90)	LIHIGKLEETSSWSAIeQSLIKLGENL.SVLSnpqLRSQADECISLIKSiptMLSA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23857 with Med24 domain of Kingdom Metazoa
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