<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23840

Description Mediator of RNA polymerase II transcription subunit 25 isoform A
SequenceMAEKQLIVAVESTAAMGPYWDTILMDYLDKMIRCFGGNDSTGQKSSASIVEFALVTYNTHGCYSSCLVQRSGWTRDPDVFFLWLSSIPFNGGGFNDAAIAEGLSEALMMLWISQSGAPNQQSVDMHKHCILVAASNPYPLQTPVYVPRPQNLEQSETIDLDSGSHLYDAEAVAKAFPQFSISLSVICPKQLPKIKTIYNAGKRNNRAADSPLEAKTPHFLILISEGFREAWGALSRSGITSLPSNQSPVKVDAVSVTPVTEAPPTSMPVNGSIPNRQPVPAGNVAPATVKVEPVLVASMVSGPAFPHNSSVPRATSTSQGVPSLQTSSLSSVSQDIITNNENAQDTKPTVSMLPLRPVNPAQANVNILNNLSIARQVMNSAALSGGTSMGLPSMSQTPVAMHMSNMISSGMTSSVPAAQNVFSSGQSGITSMTSSGPLTGPAQVGQNSGLGSLTSNTSNLSSSSNIGISQPLGNLQGAVSMGQQVSGMSQGNLSGAQMVQGGVNMNQNVMSGLGQSVVSSGTGTMIPTPGMSQPVQSGMQPLVNNAATNMPLSQQTSGGMQSAQSKYVKVWEGSLSGQRQGQPVFITKLEGYRNSSASETLAANWPPVMQIVRLISQDHMNNKQYVGKADFLVFRAMNPHGFLGQLQEKKLCAVIQLPSQTLLLSVSDKAFRLIGMLFPGDMVVFKPQLSSQQQQQHQQMQNQQQHLPQLQQQQQLPHMQQQQLPQLQQQQQLPQLQQQQQLPQLQQQQQLQQQQLPQLQQQQQLPQLQQLPQLQQQQQLPQLQQLQPQQQQMVGAGMGQAFGQGPGRSQLVSQGQVSSQGATNIGGGGFMS
Length832
PositionUnknown
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.05
Grand average of hydropathy-0.300
Instability index65.76
Isoelectric point8.42
Molecular weight89050.84
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23840
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     134.22|      15|      15|     703|     717|       1
---------------------------------------------------------------------------
  703-  717 (35.96/13.10)	QQQHLPQLQQQQQLP
  720-  734 (36.63/13.49)	QQQQLPQLQQQQQLP
  738-  750 (26.92/ 7.86)	QQQQLPQLQQQQQ..
  767-  781 (34.71/12.38)	QLQQLPQLQQQQQLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     392.41|      62|      62|     415|     476|       2
---------------------------------------------------------------------------
  236-  285 (51.85/15.00)	................RS..GITSLPS......N........QSPVKV.......DAV..SVTPV..TEAPP.....TSMPVNGSIPNRQPVpaGNVA
  286-  344 (56.72/17.04)	..PATvkvEPV.L........VASMV.......SGPAfphnsSVPRAT.......STS..QGVPS..L..QT.....SSLSSVSQDIITNN...ENAQ
  358-  414 (54.75/16.22)	VnPAQ...ANVnILNNLS..IARQVMN......SAAL.....SG...........GTS..MGLPS..MSQTPvamhmSNMISS...GMTSS.......
  415-  476 (108.69/38.74)	V.PAA...QNV.FSSGQS..GITSMTS......SGPL.....TGPAQV.......GQN..SGLGS..LTSNT.....SNLSSSSNIGISQPL..GNLQ
  479-  540 (62.51/19.46)	V.SMG...QQV......S..G...M.S......QGNL.....SG.AQMvqggvnmNQNvmSGLGQsvVSSGT.....GTMIPTP..GMSQPV.qSGMQ
  543-  606 (57.90/17.53)	VnNAA...TNM.PLSQQTsgGMQSAQSkyvkvwEGSL.....SGQRQ........GQP..VFITK..L.EGY.....RNSSASETLAANWP.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.38|      29|     126|     656|     692|       8
---------------------------------------------------------------------------
  613-  649 (41.51/24.26)	RLISQD...HMNNKQY..VG...KADFLVFRamnPhgflgQLQEK
  656-  692 (36.87/43.03)	QLPSQTlllSVSDKAFrlIGmlfPGDMVVFK...P.....QLSSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.13|      34|      38|     149|     184|       9
---------------------------------------------------------------------------
  149-  184 (48.98/40.30)	PQNLEQSETIdLDSG...SHLYDAEAVAKAfPQFSISLS
  188-  224 (54.14/34.23)	PKQLPKIKTI.YNAGkrnNRAADSPLEAKT.PHFLILIS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23840 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) FPHNSSVPRATSTSQGVPSLQTSSLSSVSQDIITNNENAQDTKPTVSMLPLRPVN
2) KVDAVSVTPVTEAPPTSMPVNGSIPNRQPVPAGNVA
3) SVPAAQNVFSSGQSGITSMTSSGPLTGPAQVGQNSGLGSLTSNTSNLSSSSNIGIS
4) SVVSSGTGTMIPTPGMSQPVQSGMQPLVNNAATNMPLSQQTSGG
5) VGAGMGQAFGQGPGRSQLVSQGQVSSQGATNIGGGGFMS
305
250
414
516
794
359
285
469
559
832










Molecular Recognition Features






MoRF SequenceStartStop




NANANA