<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23831

Description Mediator of RNA polymerase II transcription subunit 25 isoform A
SequenceMPPIISSILTLSLTDVKLGSFPIWSRPIVLSLGKRNNRAADPPLEAKTPHFLILISEGFREARGALSRSGITSLPSNQSPVKVDAVSVTPVTGAPPTSMPVNGSIPNRQPVPAGNVAPATVKVEPVPVTSMVSGPAFPHNSSVPRATSTSQGVPSLQTSSPSSVSQDIITNNETAQDTKPTVSMLPLRPVNPVQANVNILNNLSQARQVMNSAALSGGTSMGLPSMGQTPVAMHMSNMISSGMTSSVPAAQNVFSSGQSGITSMTSSGPLTVPAQVGQNSGLGSLTSNTSNLSSSSNIGISQPLGNLQGVVSIGQQVSGMSQGNLSGAQMVQGGVSMNQNVMSGLGQSVVSSGTGTMIPTPGMSQPVQSVMQPLVNNAAANMPLSQQTSGGMQSAQSKYVKVWEGILVALSSFDVLRITKWEACLDKDKDSQYLSPNLKVTGILPPLRRPTMAESNPPPPAPPCFSSSSAFAHSI
Length475
PositionUnknown
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.03
Grand average of hydropathy-0.057
Instability index63.26
Isoelectric point9.77
Molecular weight48863.09
Publications

Function

Annotated function
GO - Cellular Component
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP23831
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     131.54|      32|      37|      75|     106|       2
---------------------------------------------------------------------------
   75-  106 (59.13/24.61)	PS.NQSP..VKV...............DAVSVTPVTGAPPTSMPVNGSIP
  112-  144 (44.21/16.65)	PAgNVAPatVKV...............EPVPVTSMVSGP..AFPHNSSVP
  157-  198 (28.19/ 8.09)	QT.S.SP..SSVsqdiitnnetaqdtkPTVSMLPLRPVNPVQANVN....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      56.73|      16|      23|     311|     327|       5
---------------------------------------------------------------------------
  311-  325 (21.87/ 8.86)	.............VSIGQQV.SGMSQGNL
  326-  350 (15.51/ 6.37)	S....gaqmvqggVSMNQNVmSGLGQSVV
  369-  396 (19.35/ 7.12)	SvmqplvnnaaanMPLSQQT.SGGMQSAQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.65|      11|      17|       3|      13|       6
---------------------------------------------------------------------------
    3-   13 (18.81/ 8.57)	PIISSILTLSL
   22-   32 (21.84/10.92)	PIWSRPIVLSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.52|      13|     134|     218|     231|       7
---------------------------------------------------------------------------
  218-  231 (22.18/13.56)	GTSMGLPSMGQtPV
  355-  367 (27.34/12.87)	GTMIPTPGMSQ.PV
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP23831 with Med25 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) LSRSGITSLPSNQSPVKVDAVSVTPVTGAPPTSMPVNGSIPNRQPVPAGNVAPATVKVEP
2) PVTSMVSGPAFPHNSSVPRATSTSQGVPSLQTSSPSSVSQDIITNNETAQDTKPTVSMLPLRPVN
3) QVMNSAALSGGTSMGLPSMGQTPVAMHMSNMISSG
4) SVPAAQNVFSSGQSGITSMTSSGPLTVPAQVGQNSGLGSLTSNTSNLSSSSNIG
66
127
208
246
125
191
242
299

Molecular Recognition Features

MoRF SequenceStartStop
1) HFLILI
50
55