<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23822

Description Mediator of RNA polymerase II transcription subunit 33A
SequenceMALPAQTSEVDAWEAVLRQTKVAVDTNADPNAWALGVTSTLRSSAVTLPSVELAYRLVSFFFWDNHCATAWKLLHTAMSLNLLPSSLLMALLSATVVPSRQLYPTAYRLYMELLKQLDDMLARDFSSLYYEKIMKSIDEVLQLSQVYSQKVWEPGVVLVDFVFSIVWQLLAASLDDEGLLDHTAENKPRWLSRSHDMNIDGPDSFTEKKTEQAEGFQKKNTAIAIEIIAEFLQQKMTSRILSLVHWNMSSHWGSFIHQMQLLVSNSSVFRNLKHITAESLLRWTQNIHEVVSHELKKKSKMETNLVTPAGSLMPLAGQSYGDSWSSLWLPIDLILEDALDGAQVAAFSAIEIITGMVKTLHVVNGTMWHNTFLGLWVAALRLVQRVGIILTEKERDLKEGPIPRLDTCMCMLLSITTLVVTNIIEEEEGQLIEEPEHSPTNQGKNKLALGKCHGELITSLQLLGDYESLLTPPQLVLVEANQAAAKAIVFLSGNPVGSGCFKYMSTNDMPMKCSGNLRHLIVEACIAKKLLDTSAYLWPGYVNTCSNQIPCSISNHVSGWSSLMEGSQLTPALVNVLVATPASSYLLNDSIALYLNYSIQMRPSFHEANIRCPFLKTYKSTEFMPMDFDGSLAEIEKIYEIAINGSDEEKISAATILCGASLVRGWNVQEHTVLFITKLLSPIDPPNYSGAESHLTSQAPFLNVLLIGISSMDCVHIFSLHGLVPLLAPGLMLICEVFGSCVPDSSWTLASGEKLTHWEVFCNAFTLLLRFWRFDHLPIEQVRSDATTPPFGSLPSPECLLLVRNCKLASFGRTEKDQQRLKRWPKILCFSVEPVFMDSFPKLNFWYRKHQECIASFRSGLVPGRPVNQIVDALLSMMFKKVSNGVKPSTPTTSGSSNSSGNALDDALMKLKVPAWDILEAIPFVLDSALTSCAYGKTSTRELATGLKDLADFLPASLVTIASYFSAEVTRGIWKPSFMNGTDWPSPAANLAHIEQQIKKILAATGVNVPSLDIDGDSPATLPFPLAAFVSLTLTYKLDKATEPFLALIAPAMNAVASGCPWPSLPIVTSLWIQKVKRWSNYFVLSASSTVFHHNKDAIAQLLKSCFTSTLGLGYGSIYNNGGVSALLGDGSVSRISNGISPVAPGILYIRVYRSIGDITLLIKEIVPILMLSVTDIASSDLMPKGVVRKPKKTKFGVKYGQVSLARSMARVKHAALLGASLVWISGGQKLIQYLMRETLPSWFLSATMFEQDGGESGVMVAKLKGYALAFFVFLSAAFAWGIDNSYSPKQRAEVVGLHLKFLASTLNRNGAMFSRCTTWKAYVSGLVSLMVGQAPSWVREVDADLLKRLSWGLSQMDEHKLALRLLEIGGIGVMGAAAEMIIGFEHRS
Length1389
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.09
Grand average of hydropathy0.150
Instability index41.62
Isoelectric point6.62
Molecular weight152943.62
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23822
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     448.43|     142|     320|     726|     944|       1
---------------------------------------------------------------------------
  726-  891 (225.49/259.57)	LLAPGLMLICEVFGSCVPDSSwtlASGEKLTHWEVFCNAFTLLLRFWRFDHlpieqvrsdaTTPPFGSLPSPECLLLVRNCKLASFG.RTEKDQQRLKRWPKILCFSVEP.VFM...DSFPKLnfwYRkhqECIASfRSGLVPGRPVNQ.IVDALL.....SmmfkKVSNGVKPSTP
  993- 1145 (222.94/124.17)	HIEQQIKKILAATGVNVPSLD...IDGDSPATLPFPLAAFVSLTLTYKLDK..........ATEPFLALIAPAMNAVASGCPWPSLPiVTSLWIQKVKRWSNYFVLSASStVFHhnkDAIAQL...LK...SCFTS.TLGLGYGSIYNNgGVSALLgdgsvS....RISNGISPVAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.64|      45|     318|     895|     944|       2
---------------------------------------------------------------------------
  899-  944 (71.82/60.45)	SSGNALDDALMKLKVPAWdILEAIPFVLDSALTSCAYGKTSTRELA
 1226- 1270 (78.82/50.44)	SGGQKLIQYLMRETLPSW.FLSATMFEQDGGESGVMVAKLKGYALA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.43|      20|     318|     141|     160|       3
---------------------------------------------------------------------------
  141-  160 (35.49/21.89)	LQLSQVYSQKVWEPGVVLVD
  460-  479 (33.94/20.59)	LQLLGDYESLLTPPQLVLVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     124.75|      52|     262|     299|     359|       4
---------------------------------------------------------------------------
  299-  323 (29.62/10.29)	.............................SK.METNLVTPAGSLMP......................LAGQSYGDS
  331-  359 (23.15/25.86)	IDLILEDALDgaQVAAFSAIEIITGMVKT................................................
  591-  665 (71.99/37.42)	IALYLNYSIQ..MRPSFHEANIRCPFLKTYKsTEFMPMDFDGSLAEiekiyeiaingsdeekisaatiLCGASLVRG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.63|      34|      55|      12|      49|       6
---------------------------------------------------------------------------
   12-   49 (49.47/44.27)	AWEavLRQTkvAVDTNADPNAWALGVTS.TLRSSAVTLP
   70-  104 (54.16/35.37)	AWK..LLHT..AMSLNLLPSSLLMALLSaTVVPSRQLYP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.48|      46|      61|     189|     235|       7
---------------------------------------------------------------------------
  189-  235 (73.89/53.09)	RWLSRSHDMN..IDGPDSFTEKKTEQAEGFQKKNTAIAiEIIAEFLQQK
  251-  298 (75.58/49.81)	HWGSFIHQMQllVSNSSVFRNLKHITAESLLRWTQNIH.EVVSHELKKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.34|      17|     764|     556|     574|       8
---------------------------------------------------------------------------
  556-  574 (28.38/18.06)	HVSGWSSLMEGSqlTPALV
 1323- 1339 (32.96/15.67)	YVSGLVSLMVGQ..APSWV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23822 with Med33 domain of Kingdom Viridiplantae
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