<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23786

Description Mediator of RNA polymerase II transcription subunit 33A isoform C
SequenceMGVWDGIMQVTKLAQEKKTDPLLWSIQVSSALNSGGVSLPSIELAHRLVSHICFDNHLPMTWKFLEKAMSLRLLPPFLALSLLSSRVLPLRRLHPSAYTLYMDLLSRHAFSLLIHFPNYPSVMSSIHHLLHFSQLYSSLDPHPGVVLVLFLFTLVSQLLEASLSDEGLLQHSPRFLPVDPADIVIDNNDALRRKNTAMAIQIISRFLHHKLTSRILALVQRNMPAHWGPFLHQLQRLAANSTLLRSLKHVTPESLLPLDFNSPTGIKLLCSEWKTTPTLELNAVMADSCAVQSRHDSWSLLWLPIDLILEDAMDGNHVAEASAVEALTGLVKALQAVNGTAWHSAFLGLWIAALRLVQRERDPGEGPVPRLDTCLSMLLSITTLVVANLIEEEEGELIEEAEHSPANQRMDKQALGERHGELVTSLQLLGDYENLLTPPQSVIWGANQAAAKATLFVSGHSGYLEHTNVNDLPTNCSGNLRHLIVEACIARHLLDTSAYFWPGYVSAPFNQLPHSIPNHLPSWSSLMKGSPLTPPLVNVLVATPASSLAEIEKVFEFAIKGSDEEKISAATILCGASLVRGWNVQEHIVFFIIKMLSPPVPPKYSGTESYLISHAPFLNVFLVGISSVDSVQIFSLHGVVPLLAAVLMPICEAFGSSVPNVSWTAVTGEKLTCHAVFSNAFILLLRLWRFDRPPVEHVMGGAATPALGSQLGPEYLLLVRNCMLASYGKSPRDRVRSRRFSKMISFSLEPLFMDSFPKLNIWYRQHQECIASTCNTLAPGGPVSQIVEALLSMMCKKINRSAQSLTPTTSGSSNSSLSSLDDALMKLKVPAWDILEATPFVLDAALTACAHGRLSPRELATGLKDLADFLPATLGTIVSYLSSEVTRGIWKPAFMNGTDWPSPAANLSIVEQQIKKILAATDGNAPATLPLPLAAFLSLTITYKLDKSCERFVVLAGPSLIALSSGCPWPCMPIVGALWAQKVKRWSDFFVFSASATVFHHSRDAVVQLLRSCFASTLGLGSACIYNNGGVGTLLGHGFGSHYSGGFTPVAPGFLYLRVYRSIRDVMFLTDEIVSLLMLSVRDIANGGLPKGEVEKLKKTKYGMRYGQVSLSGSMTRVKHAALLGASFLWISGGSGLVQSLITETLPSWFLSAQGLEQEGGESGVVVAMLRGYALACFAVLGGTFAWGIDSSSPASKRRPKVLEIHLEFLANALDGKISLRCDCATWRAYVSGVMSLMVSCTPLWIQELDVGILKRMSNGLRQLNEEDLALHLLEIRGTSVMGEVAEMICQTRL
Length1294
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.08
Grand average of hydropathy0.221
Instability index46.21
Isoelectric point6.90
Molecular weight141335.52
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23786
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.36|      16|     141|     515|     533|       1
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  515-  533 (23.41/19.29)	SIPNhlPSWSSlMKGSPLT
  657-  672 (29.95/13.69)	SVPN..VSWTA.VTGEKLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     211.45|      62|      66|     866|     928|       2
---------------------------------------------------------------------------
  807-  858 (58.17/25.95)	.....PTTSGSSNSS.L..SS....LDDALMKlkvP...AWdiLEATPFVL.DAA...........LTACAHGRlSPRE
  866-  928 (107.23/56.81)	LADFLPATLGTIVSY.L..SSE...VTRGIWK...P...AF..MNGTDWPS.PAANlSIVEQQIKKILAATDGN.APAT
  933-  985 (46.05/19.15)	LAAFLSLT....ITYkLdkSCErfvVLAG......PsliAL..SSGCPWPCmPIVG.ALWAQKVKR.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     451.89|     109|     627|      51|     164|       3
---------------------------------------------------------------------------
   51-  164 (182.89/115.16)	HICFDNHLPM...TWKF....LEKAMSLRLLPPFLALSLLSSRVLPL.RRLHPSAYT.LYMDLLSRHAFSLLIHFPNYPSVMSSIHHL.LHFSQ....LYSSLDP.HPGVVLvlflfTLVSQLLEASLS
  182-  268 (122.50/66.85)	DIVIDNNDAL...RRK......NTAMAIQIISRFLHHK.LTSRILALvQRNMPAHWG.PFLHQLQRLAAN........STLLRSLKHV.TPESL....LPLDFNS.PTGIKL.................
  674-  792 (146.49/83.02)	HAVFSNAFILllrLWRFdrppVEHVMGGA.ATPALGSQLGPEYLLLV.RNCMLASYGkSPRDRVRSRRFSKMISFSLEPLFMDSFPKLnIWYRQhqecIASTCNTlAPG........GPVSQIVEALLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     217.22|      75|     685|     339|     473|       4
---------------------------------------------------------------------------
  372-  473 (99.13/137.62)	DTCLSML.LSITTLVVANLieeEEGElIEeaehspanqRMDKQALGERHGELVTSLQLL.GDYENLLTPpqSVIWganqaaakatlfVSGHSGYLEHTNVNDLP
 1071- 1147 (118.09/52.78)	DEIVSLLmLSVRDIANGGL...PKGE.VE.........KLKKTKYGMRYGQVSLSGSMTrVKHAALLGA..SFLW............ISGGSGLVQSLITETLP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23786 with Med33 domain of Kingdom Viridiplantae
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