<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23763

Description Mediator of RNA polymerase II transcription subunit 15a isoform A
SequenceMDSNNWRPNQGTNPTMDTSDWRAQLPIDSRQRIVNKIMETLKKHLPVSGPDGLHELRKIAQRFEDKIFTAATSQPDYLRKISLKMLTMETKSQNTLANNMPPNQVGPSNKPPDQGLVLQSQVHNLGQQHSIPLPGQLQPHQQLLSQNVQNNVASQPNLPPVSSLAQTPSQNIVQNSNIQNITGPNSVGTTISQNSNLQNMFPGSQRQMPGRQQIVPPQNSQQYLYQQQFKQKLQLQSQMQQQQQNLLQPNQLQSSQQSIMQTSSVMQPSMMQASSLSSIPQNQQSTNVQQPMQSMPQQHSQVIRHQQQQTSIVHQQQTAVTHQPSLPSQQQQQLMGHQPNTTNMQHAQMLGQQNNVGDIQQPQRMLSQQSNLTNLQQRQQLINQQNNPANIHQQQFGNNGPGLQQQHLLGHESGNADMQTSHHSTHMLQQPKVPMQQQSQQNTSNLLLPHSQQPQPLGSQQQLMPQIHTQSAQLQQQLGLQQQPNPSQRDMQQRIQASGSLLQQQNVLDQKKQLYQTQRTLPETSATSLDSTAQTAQPSGADWQEEVYRKLQTMKESYLPEMNEMYQKIANKLQQHDSLPQQPKSDQIDKLRAYKTMLERMMALLQIPKNNILPNFKEKLGSYEKQIINLINSNRPRKGMNSVQAGQLPPTHMSSMQQPQSQVTQVHSHENQMNPQLQSTNLQGSVPTMQQNNIASLQHNALAGVSTGQQNMMNSMQPVTNLDSGHGNSMNSLQQVPMSSLQQNPVSTPQQTNINSLPSQGGANMIQPNALQSGSSALQHQLKHQQEQQMLQSQQFKQQYQQRQQLMQRQQLLQQQQLHHPAKPQLSSQLQTHQMPQLHQMNDINDIKMRQGMGVKSGVFQQHLTSGQHSTYSHQQLKQGSAFPVSSPQLLQAASPQIQQHSSPQVDQQNHLPSKAKVTTPLQSSNSPFVGPTPSPPLAPSPMPGESEKPIPCVSSISNAANIGHQQTGGAIAPAQSLAIGTPGISASPLLAEFSAPDGAHGNALAATSGKSTVTEQPLERLINAVKSMSSKALSAAVMDIGSVVSMNDRIAGSAPGNGSRAAVGEDLVSMTNCRLQARNFITQDGSNGIKRMKRYTSAIPLNVVPSAGSMNDSIKQLTASETSDLESTATSSVKKPKIEVNHALLEEIREINHQLIDTVVDISNEDVDPTAAVAAAEGAEGIIVKCSFIAVALSPSLKSQYASAQMSPIQPLRLLVPANYPNCSPILLDKFPVESSKENDDLSVKARSKFSTSLRSLSQPMSLGEIARTWDVCARRVISEHAQQSGGGSFSSKYGTWENCLTTN
Length1305
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.03
Grand average of hydropathy-0.758
Instability index64.00
Isoelectric point9.30
Molecular weight143860.71
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23763
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.71|      18|      18|     448|     465|       1
---------------------------------------------------------------------------
  326-  343 (29.19/ 6.28)	LPSQQQQQLMGHQPNTTN
  448-  465 (37.53/10.68)	LPHSQQPQPLGSQQQLMP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.64|      20|      25|      48|      71|       6
---------------------------------------------------------------------------
   31-   59 (21.78/18.66)	QRIVNKIMETlkkhlPvSGPDglhELRKI
   61-   81 (32.86/14.02)	QRFEDKIFTA.....AtSQPD...YLRKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.63|      27|      27|     124|     150|       7
---------------------------------------------------------------------------
  113-  139 (40.07/10.93)	DQGLVLQSQVHNLGQQHSIPLPGQL..QP
  140-  168 (34.56/ 8.14)	HQQLLSQNVQNNVASQPNLPPVSSLaqTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.01|      23|      26|     879|     904|       8
---------------------------------------------------------------------------
  379-  406 (26.34/ 7.30)	QQL.INQQNnpaniHQQQFGNNGPGLQQQ
  810-  833 (29.67/ 8.67)	QQLlQQQQL.....HHPAKPQLSSQLQTH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.36|      16|      16|     921|     936|      12
---------------------------------------------------------------------------
  903-  918 (21.75/ 8.04)	SPQVDQQNHLPSKAKV
  919-  934 (26.96/12.26)	TTPLQSSNSPFVGPTP
  935-  950 (28.65/13.63)	SPPLAPSPMPGESEKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.04|      15|      16|     652|     667|      13
---------------------------------------------------------------------------
  652-  667 (21.86/ 9.69)	HMSSMqQPQSQVTQVH
  669-  683 (25.17/ 7.13)	HENQM.NPQLQSTNLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.91|      16|      16|     728|     743|      15
---------------------------------------------------------------------------
  685-  699 (22.19/ 7.01)	.SVPTMQQNNIASLQH
  728-  743 (27.92/10.89)	NSMNSLQQVPMSSLQQ
  744-  759 (26.80/10.14)	NPVSTPQQTNINSLPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.65|      26|      27|     466|     491|      16
---------------------------------------------------------------------------
  466-  491 (46.67/19.58)	QIHTQSAQLQQQLGLQQ..QPNPSQRDM
  494-  521 (36.97/13.72)	RIQASGSLLQQQNVLDQkkQLYQTQRTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.86|      27|      27|     981|    1007|      17
---------------------------------------------------------------------------
  981- 1007 (44.76/21.85)	GTPGISASP..LLA.EFSAPDGAHGNALAA
 1010- 1036 (35.56/16.01)	GKSTVTEQP..LER.LINAVKSMSSKALSA
 1042- 1064 (35.47/15.96)	GSV.VSMND..RIA.G.SAP..GNGSRAAV
 1065- 1089 (20.06/ 6.18)	GEDLVSMTNcrLQArNFITQDGSNG.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.55|      16|      88|     206|     228|      18
---------------------------------------------------------------------------
  213-  228 (31.21/18.87)	QIVPPQNSQQYLYQQQ
  293-  308 (31.35/ 6.32)	QSMPQQHSQVIRHQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.73|      24|      27|     569|     595|      20
---------------------------------------------------------------------------
  569-  595 (37.35/29.33)	IankLQQHDSLPQQPKSDQI....DKLRAYK
  597-  624 (35.39/19.57)	M...LERMMALLQIPKNNILpnfkEKLGSYE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      73.12|      20|      99|      90|     112|      21
---------------------------------------------------------------------------
   90-  112 (34.29/22.62)	TKSQNTLANNMPPnqvGPSNKPP
  190-  209 (38.82/18.49)	TISQNSNLQNMFP...GSQRQMP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.46|      18|     211|     628|     646|      24
---------------------------------------------------------------------------
  628-  646 (28.41/22.09)	INLINSNRPRKGMnSVQAG
  841-  858 (34.05/21.50)	MNDINDIKMRQGM.GVKSG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23763 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EKQIINLINSNRPRKGMNSVQAGQLPPTHMSSMQQPQSQVTQVHSHENQMNPQLQSTNLQGSVPTMQQNNIASLQHNALAGVSTGQQNMMNSMQPVTNLDSGHGNSMNSLQQVPMSSLQQNPVSTPQQTNINSLPSQGGANMIQPNALQSGSSALQHQLKHQQEQQMLQSQQFKQQYQQRQQLMQRQQLLQQQQLHHPAKPQLSSQLQTHQMPQLHQMNDINDIKMRQGMGVKSGVFQQHLTSGQHSTYSHQQLKQGSAFPVSSPQLLQAASPQIQQHSSPQVDQQNHLPSKAKVTTPLQSSNSPFVGPTPSPPLAPSPMPGESEKPIPCVSSISNA
2) KKQLYQTQRTLPETSATSLDSTAQTAQPSGADWQEEV
3) LPEMNEMYQKIANKLQQHDSLPQQPKSDQIDKLRA
4) METKSQNTLANNMPPNQVGPSNKPPDQGLVLQSQVHNLGQQHSIPLPGQLQPHQQLLSQNVQNNVASQPNLPPVSSLAQTPSQNIVQNSNIQNITGPNSVGTTISQNSNLQNMFPGSQRQMPGRQQIVPPQNSQ
5) QSQMQQQQQNLLQPNQLQSSQQSIMQTSSVMQPSMMQASSLSSIPQNQQSTNVQQPMQSMPQQHSQVIRHQQQQTSIVHQQQTAVTHQPSLPSQQQQQLMGHQPNTTNMQHAQMLGQQNNVGDIQQPQRMLSQQSNLTNLQQRQQLINQQNNPANIHQQQFGNNGPGLQQQHLLGHESGNADMQTSHHSTHMLQQPKVPMQQQSQQNTSNLLLPHSQQPQPLGSQQQLMPQIHTQSAQLQQQLGLQQQPNPSQRDMQQRIQASGSLLQ
624
511
559
88
236
960
547
593
221
503










Molecular Recognition Features






MoRF SequenceStartStop




NANANA