<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23724

Description Mediator of RNA polymerase II transcription subunit 23 isoform A
SequenceMDQSQNQRPATSTTTPSRSFQFHPLRVPIFDLFNLYLGLGRNSRQKPDDSLRDPPNKTQKRVHALNRELPPPNEQFILDFEQLQSQCADQDQLRSVTEAILISLVVQCSGHGPRADFLLFVLRSLCGIGCINWDSLLPSLLSSVSSAELPVGQLSQAVPTVSSSSLSQTGMLAPPSTIANSSNFQSSNPASPLTSVHTIGSPAQSTMEPLSCAAMSPVKSSDISSAGQQSKLRGSPSVRTNDISNSSLRQLCCKIILTGLEFSLKPVTYAEIFNYMLNWLVNWDQRQQGIDESDVIKSWRPDKAVIAWLHSCLDVIWLLVDEGKCRVPFYELLRSDLQFIENIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHCPTFGTHRILNQTIPNVSGEAVAHLRLSPITYLSVLGEPLHGEDIASSIQKGSLDWERAVRCIRHALRTTPSPDWWRRVLVLAPCYRNSSQGPTAGAVFSSEMICEATIDRIVELLKMTNSEINCWQDWLVFSDIFYFLIKSGCIDFVDFVDKLVSRLTEGDHHILKTNHVTWLLAQIIRIELVMNALNSDPRKVETTRKILSFHREDRSSDPNNPQSILLDFVSSCQNLRIWSLNSSTREYLNNEQLQKGKQIDEWWRQASKGERMMDYMNMDERSIGMFWVVTYTMAQPACETVMNWLNSAGVADLLPGANLQQAERLMATREVSPLPMSLLSGFSINLCVKLSYQMEDSLFSGQVIPSIAMVETYTRLLLLAPHSLFRSHFNHLVQRNPSLLSKPGVTLLVLEILNYRLLPLYRYQGKSKALMYDVTKIISAIKGKRGDHRVFRLAENLCLNLIFSLRDFFLVKREGKGPTEFTETLNRVTVITLAILIKTRGIADAEHLLYLQNMLEQIMATSHHTWSEKTLHHFPSVLREALSGQTDKRSLAIQTWQQAETTVIHQCTQLLSPSADPSYVMTYISHSFPQHRQYLCAGALILMHGHAENINSGNLGRVLREFSPEEVTSNIYTMVDVLLHHMQIELQQGHSSQDLMLKACASIAFFVWTNELLPLDILLLALIDRDDDPHALRMVISLLDRPELQQRVKHFCMTRGHPEHWLYSGIFKRVELQKALGNHLAWKDRYPVFFDDIAARLLPVIPLIIYRLIENDAMDTAERLLAMYSPLLAYYPLRFTFVRDILAYFYGHLPGKLIVRILNVLDISKIPFSESFPQQISLTNPVMCPPLDYFTTLLLGIVNNVIPPLHNNSKSGSMGDASSNTLRTAQSKPPAVSQSGSANASEGQKAFYQIQDPGTYTQLVLETAVIEILSLPISASQIVQSLVQIVVNIQPTLIQSSNALHGGSNSVGQGSVLPTSPSGGSTDSLGASRSTPSVSGINTSNFASRSGYTCQQLSCLLIQACGLLLAQLPSDFHSQLYLETTRIIKENWWLKDGTRSLGEIDSAVGYALLDPTWAAQDNTSTAIGNVVALLHSFFSNLPQEWLEGTNVIIKQLRPVTSVAMLRIAFRVMGPLLPKLANAHALFNKTLSSLLTILVDVFGKNSQTSIAVDASDIADIIDFLHHVVHYEGQGGPVQASSKPRPEVLALIGRASESLRPDIQHLLSHLNPDVNSSVYAAFHPKLAQNPT
Length1615
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.07
Grand average of hydropathy-0.059
Instability index46.76
Isoelectric point6.47
Molecular weight180599.28
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23724
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.55|      20|     180|     317|     341|       1
---------------------------------------------------------------------------
  317-  341 (31.50/32.26)	WLLVDEgkcrvPFYELLRSD.LQFIE
  504-  524 (33.05/19.92)	WLVFSD.....IFYFLIKSGcIDFVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.17|      21|     540|     999|    1019|       4
---------------------------------------------------------------------------
  999- 1019 (38.25/27.64)	SNIYTMVDVLLHHMQIELQQG
 1540- 1560 (38.91/28.26)	SDIADIIDFLHHVVHYEGQGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     294.48|      80|     326|    1084|    1167|       5
---------------------------------------------------------------------------
  752-  823 (88.44/59.27)	......HSLFRSHF..........NHLV..QRNPSLLSKPGVTLL.VLEILNYRLLPLYRYQGKSKAL.MYDVTKIISAIKgkrgdhrvFRL
  824-  879 (74.92/48.62)	AENLCLNLIFS..LRDFFLVK.......REGKGPTEFTETLNR.VTVITLAI..LIKTRGIADAEHLL........................
 1084- 1167 (131.12/104.46)	TRGHPEHWLYSGIFKRVELQKalgNHLAWKDRYPVFFDDIAARLLPVIPLIIYRLIENDAMDTAERLLaMYSPLLAYYPLR........FTF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.07|      36|      40|      16|      52|       6
---------------------------------------------------------------------------
   16-   52 (59.96/45.39)	PSRSFQ..FHPL..RVPIFDlFNLYLGLGRNSRQKPD.DSLR
   54-   94 (50.11/32.44)	PPNKTQkrVHALnrELPPPN.EQFILDFEQLQSQCADqDQLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     330.45|     107|     790|     584|     706|       7
---------------------------------------------------------------------------
  546-  651 (136.41/106.34)	VTWLLAQ..iirIELVMNAL....NS....D..P........RKVETTR...KILSFHR...edRSSDPNNPQSILLdfVSSCqNLRIWSLNSS..TREYLNNEQLQKgkqiDEWWRQasKGERMMD.......YMNMDER
  659-  706 (59.02/29.89)	VTYTMAQPA...CETVMNWL....NSAGVADLLP.GANLQQAERLMATR...EVSPLPM..................................................................................
 1320- 1442 (135.02/74.39)	......QPT...LIQSSNALhggsNSVGQGSVLPtSPSGGSTDSLGASRstpSVSGINTsnfasRSGYTCQQLSCLL..IQAC.GLLLAQLPSDfhSQLYLETTRIIK....ENWWLK..DGTRSLGeidsavgYALLDPT
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23724 with Med23 domain of Kingdom Viridiplantae
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