<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23723

Description Mediator of RNA polymerase II transcription subunit 23 isoform B
SequenceMDQSQNQRPATSTTTPSRSFQFHPLRVPIFDLFNLYLGLGRNSRQKPDDSLRDPPNKTQKRVHALNRELPPPNEQFILDFEQLQSQCADQDQLRSVTEAILISLVVQCSGHGPRADFLLFVLRSLCGIGCINWDSLLPSLLSSVSSAELPVGQLSQAVPTVSSSSLSQTGMLAPPSTIANSSNFQSSNPASPLTSVHTIGSPAQSTMEPLSCAAMSPVKSSDISSAGQQSKLRGSPSVRTNDISNSSLRQLCCKIILTGLEFSLKPVTYAEIFNYMLNWLVNWDQRQQGIDESDVIKSWRPDKAVIAWLHSCLDVIWLLVDEGKCRVPFYELLRSDLQFIENIPDDEALFTLILEIHRRRDMMAMHMQMLDQHLHCPTFGTHRILNQTIPNVSGEAVAHLRLSPITYLSVLGEPLHGEDIASSIQKGSLDWERAVRCIRHALRTTPSPDWWRRVLVLAPCYRNSSQGPTAGAVFSSEMICEATIDRIVELLKMTNSEINCWQDWLVFSDIFYFLIKSGCIDFVDFVDKLVSRLTEGDHHILKTNHVTWLLAQIIRIELVMNALNSDPRKVETTRKILSFHREDRSSDPNNPQSILLDFVSSCQNLRIWSLNSSTREYLNNEQLQKGKQIDEWWRQASKGERMMDYMNMDERSIGMFWVVTYTMAQPACETVMNWLNSAGVADLLPGANLQQAERLMATREVSPLPMSLLSGFSINLCVKLSYQMEDSLFSGQVIPSIAMVETYTRLLLLAPHSLFRSHFNHLVQRNPSLLSKPGVTLLVLEILNYRLLPLYRYQGKSKALMYDVTKIISAIKGKRGDHRVFRLAENLCLNLIFSLRDFFLVKREGKGPTEFTETLNRVTVITLAILIKTRGIADAEHLLYLQNMLEQIMATSHHTWSEKTLHHFPSVLREALSGQTDKRSLAIQTWQQAETTVIHQCTQLLSPSADPSYVMTYISHSFPQHRQYLCAGALILMHGHAENINSGNLGRVLREFSPEEVTSNIYTMVDVLLHHMQIELQQGHSSQDLMLKACASIAFFVWTNELLPLDILLLALIDRDDDPHALRMVISLLDRPELQQRVKHFCMTRGHPEHWLYSGIFKRVELQKALGNHLAWKDRYPVFFDDIAARLLPVIPLIIYRLIENDAMDTAERLLAMYSPLLAYYPLRFTFVRDILAYFYGHLPGKLIVRILNVLDISKIPFSESFPQQISLTNPVMCPPLDYFTTLLLGIVNNVIPPLHNNSKSGSMGDASSNTLRTAQSKPPAVSQSGSANASEGQKAFYQIQDPGTYTQLVLETAVIEILSLPISASQIVQSLVQIVVNIQPTLIQSSNALHGGSNSVGQGSVLPTSPSGGSTDSLGASRSTPSVSGINTSNFASRSGYTCQQLSCLLIQACGLLLAQLPSDFHSQLYLETTRIIKENWWLKDGTRSLGEIDSAVGYALLDPTWAAQDNTSTAIGNVVALLHSFFSNLPQEWLEGTNVIIKQLRPVTSVAMLRIAFRVMGPLLPKLANAHALFNKVQRITNSQS
Length1523
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.08
Grand average of hydropathy-0.068
Instability index47.98
Isoelectric point6.65
Molecular weight170783.31
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23723
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.55|      20|     180|     317|     341|       1
---------------------------------------------------------------------------
  317-  341 (31.50/35.02)	WLLVDEgkcrvPFYELLRSD.LQFIE
  504-  524 (33.05/21.72)	WLVFSD.....IFYFLIKSGcIDFVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.36|      32|     342|    1105|    1171|       3
---------------------------------------------------------------------------
  848-  879 (53.34/21.92)	PTEFTETLNR.VTVITLAI..LIKTRGIADAEHLL
 1117- 1151 (46.02/68.37)	PVFFDDIAARlLPVIPLIIyrLIENDAMDTAERLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.96|      19|     110|     546|     565|       7
---------------------------------------------------------------------------
  546-  565 (30.01/23.79)	VTWLLAQIIrIELVMNALNS
  659-  677 (38.95/26.09)	VTYTMAQPA.CETVMNWLNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     301.03|      93|     110|     891|     988|      11
---------------------------------------------------------------------------
  891-  988 (161.72/97.75)	TSH.HTWSEKTLHHFPSVLREALSGQ....TDKRSLAIQTWQQAETTVIHQCTQLLSPSADP...SYVMTYISHSFPQHR.QYLCagaliLMHGHAEN.INSGNLGRV
  998- 1100 (139.30/75.86)	TSNiYTMVDVLLHHMQIELQQGHSSQdlmlKACASIAFFVWTNELLPLDILLLALIDRDDDPhalRMVISLLDRPELQQRvKHFC.....MTRGHPEHwLYSGIFKRV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.07|      36|      39|      16|      52|      12
---------------------------------------------------------------------------
   16-   52 (59.96/40.27)	PSRSFQ..FHPL..RVPIFDlFNLYLGLGRNSRQKPD.DSLR
   54-   94 (50.11/28.76)	PPNKTQkrVHALnrELPPPN.EQFILDFEQLQSQCADqDQLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     186.34|      60|     789|     584|     657|      18
---------------------------------------------------------------------------
  584-  657 (88.09/107.34)	RSSDPNNPQSILLdfVSSCqNLRIWSLNSS..TREYLNNEQLQKgkqiDEWWRQasKGERMMD.......YMNMDERsigmfW
 1375- 1443 (98.25/72.24)	RSGYTCQQLSCLL..IQAC.GLLLAQLPSDfhSQLYLETTRIIK....ENWWLK..DGTRSLGeidsavgYALLDPT.....W
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23723 with Med23 domain of Kingdom Viridiplantae
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