<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23712

Description Mediator of RNA polymerase II transcription subunit 15a isoform A
SequenceMDNNNWRPNQGTEANMDTSDWRGGLHHESRQRIVNKIMDTLKRHLPVTGQEGLHELQKIAQRFEEKIFTAATSQSDYLRKISLKMLTMETKSQGSMAPNLPTNQGGPSNKPPDPGLGIPPQVHNPGQQHPIPMPNQPPNRQQLLPQNIQNSIASQPSNIAQAPIQNVGQNNPNMQNIPGQNSVGSTISQNSNMQNMFPGSQRQIQGRQQVVPQQQQQQSQNSQQYIYQQQMQHQLLRQKLQQQQQQQQQQQQQQQQQQQQQQNLLQSNQLQSSQQPAIQTSTVMQQPSMMQASLPSIQHNQQSNNQQSTQSVLQQHSQVIRQQQHQQTSIIHQQQTPMTQQSILPTQQQQQQQLMGAQANAPNMHHTQILGSQNNVGDLQQPQRLLTQQNNLSNLQQQQLINQQNNLSNMHQQLGNNVPGLQPQQVLGPQSGNSGMQTSQHSAHVLQQSQQNASNLLPSQVQQSQPQAPQQQLMPQIQSQPAQLQQQLGLQQQPNPLQRDVQQRLQASGPLLQQSNVLDQQKQLYQSQRPLPETSSTSLDSTAQTGQSSGGDWQEEVYQKIKSMKESYLPELNEMYQKIVSKLQQHDSLPQQPKSDQLEKLKVFKMMLERIITFLQVSKSNISPNFKEKLNSYEKQIINFINTNRPRKNMPGHLLPPHMHSMPQSQPQVTQVQSHENQMNPQLQTTNMQGSVATMQQNNMAGMQHNSLSGVSTVQQSKMNSMQPSTNLDSGPGNAVNSLQQVPVSSLQQNPVSAPQQTNVNSLSSQAGVNVVQPNLNPLQPGSSMLQHQQLKQQQEQQMLQNQQLKQQYQRQLLQRKQQQMLQQQQQQQQQQQQLHQTSKQQLPAQLPTHQIQQLHQMNDANDIKMRQGIGVKPGVFQQHLTSSQRSAYPHQQMKGSPFPVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVATPLQSANSPFGVPTPSPPLAPSPMPGDSEKLISGVSSISNAANIGYQQTGGAAAPGQSLAIGTPGISASPLLAEFTGPDGAHGNSLAPTSGKSTVTEQPIERLIKAVKSMSPKALSSAVSDIGSVVSMNDRIAGSAPGNGSRAAVGEDLVAMTNCRLQARNFITQDGANGTRRMKRYTNATPLNVVTSAGSMNDSIKQLAAEASDLDSTATSRFKMPRIEANHSLLEEIREVNQRLIDTVVDISNEEVDPTAAAAAAEGTEGTIVKCSYNAVALSPSLKSQYASAQMSPIQPLRLLVPTNYPNCSPILLDKFPVESSKENEDLSVKAKSRFSISLRSLSQPMSLGEIARTWDVCARTVISEHAQQSGGGSFSSKYGTWENCLTT
Length1319
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.03
Grand average of hydropathy-0.850
Instability index71.45
Isoelectric point9.38
Molecular weight145772.05
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23712
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            11|     996.04|      89|      89|     334|     422|       1
---------------------------------------------------------------------------
   93-  186 (80.83/12.91)	.Q..GSMAPN..LPTN............Q...GGPSNkppdpglgiPPQVHNP.....GQ.....QHPIPMPNQPpnrQQLLPQniQNSIasqpSNIA..QA.PIQNvGQNN...PN..MQNIPGQNSVG..ST
  189-  266 (115.42/22.36)	QN..SNM..QNMFPGSQ.RQ.......IQ...GRQQV.........VPQQQQQ..QSQNS.....QQYIYQQQMQ...HQLLRQ..K..L....QQQQ..QQ.Q..Q.QQQQ..QQQ..QQQQQQQNL....LQ
  268-  332 (80.29/12.76)	NQ..LQSSQQPAIQTSTvMQ.......QPSMM..QAS.........LPSIQHN..Q.........QSN..NQQST...Q...............SVLQ..QHsQVIR.QQ.Q........HQQ....TSI..IH
  334-  422 (161.32/34.90)	QQ..TPMTQQSILPTQQ.QQ.......QQQLMGAQAN.........APNMHHT..QILGS.....QNNVGDLQQP...QRLLTQ..QNNL....SNLQ..QQ.QLIN.QQNN..LSN..MHQQLGNNVPG..LQ
  424-  506 (94.78/16.72)	QQvlGPQSGNSGMQTSQ.HS.......AHVLQQSQQN.........ASNLLPS..QVQQS.....QP.....QAP..qQQLMPQ.iQSQP....AQLQ..QQ.LGLQ.QQPN..........PLQRDVQQ.rLQ
  507-  584 (74.30/11.12)	AS..GPLLQQSNVL....DQ.......QKQLYQSQRP.........LPETSST..S.LDStaqtgQSSGGDWQEE.vyQKI.............KSMK..ES.YL.....PE..LNE..MYQKI...VSK..LQ
  585-  656 (65.82/ 8.80)	QH..DS......LP.QQ.PK.......SDQL..EKLK.........VFKMMLE..RIITF...........LQVS...KSNISPnfKEKL.....NSY..EK.QIIN.FIN....TN..RPRK...NMPGhlLP
  658-  740 (96.45/17.17)	HM..HSMPQSQPQVTQV.QS.......HENQMNPQLQ.........TTNMQ.......GS........VATMQQN...NMAGMQ..HNSL....SGVStvQQ.SKMN.SMQP..STN..LDSGPGNAVNS..LQ
  745-  817 (66.89/ 9.10)	............................SSLQQNPVS.........APQQTNV..NSLSS.....QAGV.NVVQP...N.LNPL..QPGS....SMLQ..HQ.QLKQ.QQEQqmLQNqqLKQQYQRQLLQ..RK
  818-  877 (81.16/13.00)	QQ...QMLQQ.....QQ.QQ.......QQQ................QQQLHQTskQQLPA.....QLPTHQIQQ.......LHQ.....................MN.DAND..I.K..MRQGIGVK.PG..VF
  879-  949 (78.77/12.34)	QH..LTSSQRSAYPHQQ.MKgspfpvsSPQLL..QAT.........SP.......QI..P.....QHS.....SP...Q..VDQ..QNHL....PSLT..K.......VATP..LQS..ANSPFG..VPT....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     122.92|      25|      26|     982|    1006|       2
---------------------------------------------------------------------------
  982- 1006 (42.36/22.91)	QQTGGAAAPGQSLA..IGTPGI....SASPL
 1009- 1035 (33.17/16.31)	EFTGPDGAHGNSLAptSGKSTV....TEQPI
 1074- 1092 (21.31/ 7.80)	..NGSRAAVGEDLV..AMTN........CRL
 1093- 1118 (26.08/11.22)	QARNFITQDG...A..NGTRRMkrytNATPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.70|      15|      16|    1039|    1053|       3
---------------------------------------------------------------------------
 1039- 1053 (24.36/20.09)	IKAVKSMSPKALSSA
 1057- 1071 (25.34/21.29)	IGSVVSMNDRIAGSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.74|      13|     115|    1137|    1149|       6
---------------------------------------------------------------------------
 1137- 1149 (23.17/20.08)	EASDLDSTATSRF
 1254- 1266 (22.56/19.33)	ENEDLSVKAKSRF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23712 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IINFINTNRPRKNMPGHLLPPHMHSMPQSQPQVTQVQSHENQMNPQLQTTNMQGSVATMQQNNMAGMQHNSLSGVSTVQQSKMNSMQPSTNLDSGPGNAVNSLQQVPVSSLQQNPVSAPQQTNVNSLSSQAGVNVVQPNLNPLQPGSSMLQHQQLKQQQEQQMLQNQQLKQQYQRQLLQRKQQQMLQQQQQQQQQQQQLHQTSKQQLPAQLPTHQIQQLHQMNDANDIKMRQGIGVKPGVFQQHLTSSQRSAYPHQQMKGSPFPVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVATPLQSANSPFGVPTPSPPLAPSPMPGDSEKLISG
2) MDNNNWRPNQGTEANMDTSDWRGGLHHESRQRIVNKIMDTLKRHLPVTGQEGLHELQKIAQRFEEKIFTAA
3) NVLDQQKQLYQSQRPLPETSSTSLDSTAQTGQSSGGDWQEE
4) PLLAEFTGPDGAHGNSLAPTSGKSTVTEQPIERLI
5) QQHQQTSIIHQQQTPMTQQSILPTQQQQQQQLMGAQANAPNMHHTQILGSQNNVGDLQQPQRLLTQQNNLSNLQQQQLINQQNNLSNMHQQLGNNVPGLQPQQVLGPQSGNSGMQTSQHSAHVLQQSQQNASNLLPSQVQQSQPQAPQQQLMPQIQSQPAQLQQQLGLQQQPNPLQRDVQQRLQASGPLLQ
6) QQQQQQQNLLQSNQLQSSQQPAIQTSTVMQQPSMMQASLPSIQHNQQSNNQQSTQSVLQQHSQ
7) RKISLKMLTMETKSQGSMAPNLPTNQGGPSNKPPDPGLGIPPQVHNPGQQHPIPMPNQPPNRQQLLPQNIQNSIASQPSNIAQAPIQNVGQNNPNMQNIPGQNSVGSTISQNSNMQNMFPGSQRQIQGRQQVVPQQQQQQSQNSQQYIYQ
637
1
516
1005
323
256
79
969
71
556
1039
513
318
228










Molecular Recognition Features






MoRF SequenceStartStop




NANANA