<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23707

Description Mediator of RNA polymerase II transcription subunit 15a isoform B
SequenceMDNNNWRPNQGTEANMDTSDWRGGLHHESRQRIVNKIMDTLKRHLPVTGQEGLHELQKIAQRFEEKIFTAATSQSDYLRKISLKMLTMETKSQGSMAPNLPTNQGGPSNKPPDPGLGIPPQVHNPGQQHPIPMPNQPPNRQQLLPQNIQNSIASQPSNIAQAPIQNVGQNNPNMQNIPGQNSVGSTISQNSNMQNMFPGSQRQIQGRQQVVPQQQQQQSQNSQQYIYQQQMQHQLLRQKLQQQQQQQQQQQQQQQQQQQQQQNLLQSNQLQSSQQPAIQTSTVMQQPSMMQASLPSIQHNQQSNNQQSTQSVLQQHSQVIRQQQHQQTSIIHQQQTPMTQQSILPTQQQQQQQLMGAQANAPNMHHTQILGSQNNVGDLQQPQRLLTQQNNLSNLQQQQLINQQNNLSNMHQQLGNNVPGLQPQQVLGPQSGNSGMQTSQHSAHVLQQSQQNASNLLPSQVQQSQPQAPQQQLMPQIQSQPAQLQQQLGLQQQPNPLQRDVQQRLQASGPLLQQSNVLDQQKQLYQSQRPLPETSSTSLDSTAQTGQSSGGDWQEEVYQKIKSMKESYLPELNEMYQKIVSKLQQHDSLPQQPKSDQLEKLKVFKMMLERIITFLQVSKSNISPNFKEKLNSYEKQIINFINTNRPRKNMPGHLLPPHMHSMPQSQPQVTQVQSHENQMNPQLQTTNMQGSVATMQQNNMAGMQHNSLSGVSTVQQSKMNSMQPSTNLDSGPGNAVNSLQQVPVSSLQQNPPGSSMLQHQQLKQQQEQQMLQNQQLKQQYQRQLLQRKQQQMLQQQQQQQQQQQQLHQTSKQQLPAQLPTHQIQQLHQMNDANDIKMRQGIGVKPGVFQQHLTSSQRSAYPHQQMKGSPFPVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVATPLQSANSPFGVPTPSPPLAPSPMPGDSEKLISGVSSISNAANIGYQQTGGAAAPGQSLAIGTPGISASPLLAEFTGPDGAHGNSLAPTSGKSTVTEQPIERLIKAVKSMSPKALSSAVSDIGSVVSMNDRIAGSAPGNGSRAAVGEDLVAMTNCRLQARNFITQDGANGTRRMKRYTNATPLNVVTSAGSMNDSIKQLAAEASDLDSTATSRFKMPRIEANHSLLEEIREVNQRLIDTVVDISNEEVDPTAAAAAAEGTEGTIVKCSYNAVALSPSLKSQYASAQMSPIQPLRLLVPTNYPNCSPILLDKFPVESSKENEDLSVKAKSRFSISLRSLSQPMSLGEIARTWDVCARTVISEHAQQSGGGSFSSKYGTWENCLTT
Length1290
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.03
Grand average of hydropathy-0.863
Instability index71.67
Isoelectric point9.38
Molecular weight142785.80
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23707
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            10|     940.81|      89|      89|     334|     422|       1
---------------------------------------------------------------------------
   93-  186 (77.48/12.21)	.Q..GSMA.......PN..LPTN......Q...GGPSNkppdpglgiPPQVHNP...GQ.....QHPIPMPNQPpnrQQLLPQniQNSIasqpSNIAQA.PIQNvGQNN.PNMQ....N.....IPGQN...SVG..ST
  189-  266 (116.73/23.24)	QN..SNM.........QNMFPGSQ..RQIQ...GRQQV.........VPQQQQQQSQNS.....QQYIYQQQMQ...HQLLRQ..K..L....QQQQQQ.Q..Q.QQQQQQQQQ....Q.....QQQQN...L....LQ
  268-  332 (81.26/13.27)	NQ..LQSS.......QQPAIQTST.vMQQPSMM..QAS.........LPSIQHNQ.........QSN..NQQST...Q...............SVLQQHsQVIR.QQ.Q....H....Q.....Q.......TSI..IH
  334-  422 (160.94/35.66)	QQ..TPMT.......QQSILPTQQ..QQQQQLMGAQAN.........APNMHHTQILGS.....QNNVGDLQQP...QRLLTQ..QNNL....SNLQQQ.QLIN.QQNNLSNMH....Q.....QLGNN...VPG..LQ
  424-  506 (97.31/17.78)	QQvlGPQS.......GNSGMQTSQ..HSAHVLQQSQQN.........ASNLLPSQVQQS.....QP.....QAP..qQQLMPQ.iQSQP....AQLQQQ.LGLQ.QQPN...............PLQRD...VQQ.rLQ
  507-  584 (74.65/11.41)	AS..GPLL.......QQSNVL.....DQQKQLYQSQRP.........LPETSSTS.LDStaqtgQSSGGDWQEE.vyQKI.............KSMKES.YL.....PELNEMY....Q.....KI......VSK..LQ
  585-  656 (63.97/ 8.41)	QH..DS.............LP.QQ..PKSDQL..EKLK.........VFKMMLERIITF...........LQVS...KSNISPnfKEKL.....NSYEK.QIIN.FIN..TNRP....R.....K...N...MPGhlLP
  660-  740 (98.95/18.24)	HS..MPQS.......QPQV..TQV..QSHENQMNPQLQ.........TTNMQGSVATMQ.....QNNMAGMQH........NS..LSGV....STVQQS.KMNS.MQPS.TNLD....S.....GPGNA...VNS..LQ
  748-  824 (92.31/16.38)	QQ..NP.P.......GSSMLQHQQlkQQQEQQM.LQ.................NQQLK.............QQY...QRQLLQ..RKQQ....QMLQQQ.Q..Q.QQQQQQQLHqtskQ.....QLPAQ...LPThqIQ
  825-  919 (77.20/12.13)	QL..HQMNdandikmRQGIGVKPG..VFQQHLTSSQRS.........A..YPHQQMKGS.....PFPVS...SP...QLLQAT..SPQI....PQHSSP.Q.VD.QQNHLPSLT....KvatplQSANSpfgVP.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     122.92|      25|      26|     953|     977|       2
---------------------------------------------------------------------------
  953-  977 (42.36/22.68)	QQTGGAAAPGQSLA..IGTPGI....SASPL
  980- 1006 (33.17/16.14)	EFTGPDGAHGNSLAptSGKSTV....TEQPI
 1045- 1063 (21.31/ 7.71)	..NGSRAAVGEDLV..AMTN........CRL
 1064- 1089 (26.08/11.10)	QARNFITQDG...A..NGTRRMkrytNATPL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.70|      15|      15|    1010|    1024|       3
---------------------------------------------------------------------------
 1010- 1024 (24.36/16.45)	IKAVKSMSPKALSSA
 1028- 1042 (25.34/17.44)	IGSVVSMNDRIAGSA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.12|      17|      21|      48|      68|       4
---------------------------------------------------------------------------
   22-   38 (29.56/16.18)	RGGLH..HESRQRIVNKIM
   50-   68 (25.56/29.19)	QEGLHelQKIAQRFEEKIF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.74|      13|     116|    1108|    1120|       6
---------------------------------------------------------------------------
 1108- 1120 (23.17/16.85)	EASDLDSTATSRF
 1225- 1237 (22.56/16.22)	ENEDLSVKAKSRF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23707 with Med15 domain of Kingdom Viridiplantae
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