<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23700

Description Mediator of RNA polymerase II transcription subunit 16 isoform A
SequenceMNQIAAIKDPEEGSEKKKKSNEAISGEEKKEDPMEQEMESLTPATVFCIRLKQPKSNLLYKMSVPEICRNFSAVSWCGKLNAIACASETCARIPSSTGNPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFIEWSPTCCPRALLVANFHGRVTIWTQPSQGQANLALDASCWLREHEWRQDIAVVTKWLSGVSLYRWLSSKPSGPANSRSTFEEKFLSQQCQTSARWPNFLCVCSVLSSGSVQLHWSQWPPQNATPPKWFCTSKGPLGCGPSGIMAGDAIITDSGAMHVAGVPIVNPSTIVVWEVMPGPGNGFQVIPRTSTNNGVPPPLSSPNWTGFAPLAAYLFSWQDHLLSEEKQGKNQTNQNLGDSIPLNCSPVSNFSAYVSPETAAQTAATTTWGSGVTAVAFDPTCGGSVIAVVIAEGQYMSPYDPDEGPSITGWRVQLWESSLQHVVLHPIFGNPTSSMGGQPPMQTVWQTKVDLSIPPTNDFKNHQAPAVGMNTDIQKVSEFGFDKSKRVNFDPFDLPSDVRALARIVYSPHGGEIAIAFLRGGVHIFSGPNFAPVDNYQISVGSAIAAPAFSSTSCCSASVWHDPSKDQTILKIIRVLPPAIPTSQVKTNSSNWERAIAERFWWSLLVGVNWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSAQHRQQYCPSLDRIKCRLLEGANAQEVRAMVLDMQARLLLDMLGKGIESALINPSALVPDPWQVSSETLTSIDPEAVAVEPALVPCVQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGTGNNRNVVASPAQCSATPATSQGGQNGTTSSSGSTQMQAWVQGAIAKISSTTDGVSNPVPNPPISGPSSFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRAQQPRYAGGVQRTADTNLQKPQPNASVPGKVEEIAKPVSTVVRPDDGQAGRVSQLVPASKGGEEPSPGRSRIGTGNAGLGYTYEEVKVLFLVLMDLCRRTAGLQHPLPVSQVGSNNIQVRLHYIDGNYTVLPEVVEAALGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDPDDLDSANDAPKLISLNPLDSSSLENCDVYYGANGLWPRKRRMSERDAAFGLNTSVGLGAYLGIMGSRRDVVTALWKTGLEGIWYKCIRCLRQTCAFASPASTNLPSQNDREIWWISRWAYGCPMCGGTWVRVV
Length1226
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.08
Grand average of hydropathy-0.178
Instability index44.34
Isoelectric point6.39
Molecular weight133035.47
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23700
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     280.46|      62|     137|     236|     307|       1
---------------------------------------------------------------------------
  236-  300 (112.36/53.42)	CSVLSSGSVQLH.WSQ..WPPQNATPPKW....FCTSKGPLGCGPSGIMagdAIITDSGAMHVAGVPIVNPS
  376-  438 (95.34/38.84)	CSPVSNFSAYVS..PE..TAAQTAATTTWgsgvTAVAFDP.TCGGSVI....AVVIAEGQYMSPYDPDEGPS
  830-  885 (72.77/29.16)	....SSGSTQMQaWVQgaIAKISSTTDGV....SNPVPNPPISGPSSFM...PISINTGTF..PGTPAV...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     507.36|     163|     572|     451|     648|       2
---------------------------------------------------------------------------
  451-  648 (246.55/215.38)	LQH.............VVLHPIFGNPT.......SSMGgqPPMQtvwqtkvDLSIPPTND........FKNHqAPAvgmnTDIQKVSEFGFDKSkrvnfDPFDLPSDVRALARIVYSPhggeIAIAFLRgGVHIFSGPN.FAP....VDNYQISVG..SAIAAPAF....SSTSCCSASVWHdPSKDQTILKIIRVLPPAIP.TSQVKTN.SSNWERAIaerfWWsllvgVNWWdAVGC
 1012- 1215 (260.81/148.69)	LQHplpvsqvgsnniqVRLHYIDGNYTvlpevveAALG..PHMQ.......NMPRPRGADaaglllreLELH.PPA....EEWHRRNMFGGPWS.....DPDDLDSANDAPKLISLNP....LDSSSLE.NCDVYYGANgLWPrkrrMSERDAAFGlnTSVGLGAYlgimGSRRDVVTALWK.TGLEGIWYKCIRCLRQTCAfASPASTNlPSQNDREI....WW.....ISRW.AYGC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.64|      28|     115|     776|     804|       3
---------------------------------------------------------------------------
  776-  804 (47.20/32.82)	HFITRLRRYASFCRTL..ASHAVTAGtGNNR
  892-  921 (50.44/30.69)	HFLHRLCQLLLFCFFFrrAQQPRYAG.GVQR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      44.36|      12|      14|     157|     168|       7
---------------------------------------------------------------------------
  157-  168 (21.96/11.54)	WTQPSQGQANLA
  174-  185 (22.41/11.94)	WLREHEWRQDIA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23700 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MNQIAAIKDPEEGSEKKKKSNEAISGEEKKEDPMEQE
1
37










Molecular Recognition Features






MoRF SequenceStartStop




1) MNQIAA
1
6