<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23698

Description Mediator of RNA polymerase II transcription subunit 33A isoform A
SequenceMLGLWGMECVAEMTKVAQQKGSDPLLWAVQMYSNLNSAGESLPSLQLAEFLVSYICWDNNVPILWKFLEKALTLQIVPPMLLLALLSVRVIPCRHVQPAAYRLYLELVKRHAFELKSQINRPDYQKVMKSIDAVLHLSNIFGMPQSEPGILVVEFIFSIVWQLLDASLDDEGLLEFTPDKKSRWATLYHDMELDRHDNYSEQRTEHHEKLQNANTLMAVEMIGQFLQDKISSRLLYLARQNLPAHWLSFTQRLQLLGANSLALRKSRTLSPEALLQLTSDSCMVLSRECKTNSQKKFQTVMSFEYLSSSASLCHGASHSALWIPLDLVLEDSMDGYQVSATSAIETISGLIKTLRAINGTSWHDTFLGLWLATLRLVQRERDPIDGPMPHLETRLCMLLCIIPLVVGDLIEEEEERTPVDEKDNGPTGCWKEKKVAGKCRDDLVSSLQVLGDYQSLLTPPQPVLAAANQAAAKAMLFVSGITIGSAYFDCLNMTEMPVDCSGNMRHLIVEACIARNLLDTSAYLWPGYVNGRINQIPQCMPAQVPGWSSFMKGTPLTSVMVNALVSSPATSLAELEKIFEIAIEGSEDEKISAAAILCGASLICGWNIQEHTVHFILRLLSPPVPAENTEGNNYLINYAPILNVLFVGIASVDCVQIFSLHGLVPQLACSLMPICEVFGSCVPNISWTLTSGEEISAHAVFSNAFILLLKLWRFNRPPLEYGIGDVPTVGSQLTPEYLLLVRNSHLMSAGNIHKDRNRRRLSEIASLSSPNSVFVDSFPKLKVWYRQHQACIASTLSGLVHGTPFHQIVEGLLNMMFRKINRGSQTTITSGSSSSSGPANEDASIGPKLPAWDILEAIPFVVDAALTACAHGRLSPRELATGLKDLADFLPASLATIISYFSAEVTRGVWKPVFMNGTDWPSPAANLLNVEGQIRKILAATGVDVPSLASGDSCPATLPLPLAAFTSLTITYKVDKASERFLNLAGQTLESLAAGCPWPCMPIVASLWTLKAKRWSDFLIFSASRTVFLHNSDAAVQLLKSCFTATLGMNSSPISSSGGVGALLGHGFKYHLCGGLCPVAPGILYLRAYGSIRDVVFLTEEIVSILMHSVREIVCSGLPRDRLEKLKANKDGIKYGQVSLAASMTRVKLAAALGASLVWISGGLMLVQLLIKETLPSWFISVQRLDQEEKSGGMVAMLGGYALAYFAVLCGAFAWGVDSSSSASKRRPKVLGTHMEFLASALDGKISLGCDSATWRAYVSGFVSLMVGCTPNWVLEVDVHVLKRLSNGLRQLNEEELALALLGVGGVGTMDAAAELIIDTEI
Length1322
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.08
Grand average of hydropathy0.190
Instability index44.10
Isoelectric point5.98
Molecular weight144515.95
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23698
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     342.23|      89|     363|     513|     605|       1
---------------------------------------------------------------------------
  513-  605 (141.33/90.02)	IARNLLDTSAYL......................WPGYVNGRINQIPQCMPA.......QVP..GWSS.FMKGTPLTSVMVNALvSSPATSLaeLEKIFeIAIEGSEDEKISAAAILCGASLICG
  883-  951 (89.76/46.92)	....LKDLADFL.......................P....ASLATIISYFSA.......EVTrgVWKPvFMNGTDWPSPAANLL.................NVEG.QIRKILAATGVDVPSLASG
  955- 1065 (111.14/59.85)	PATLPLPLAAFTsltitykvdkaserflnlagqtLESLAAG..CPWP.CMPIvaslwtlKAK..RWSD.FLIFSASRTVFLHN..SDAAVQL..LKSCF.TATLGMNSSPISSSG...GVGALLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.92|      18|     363|       2|      25|       2
---------------------------------------------------------------------------
    2-   25 (23.56/33.47)	LGLWgmecVAEMTKVaqQKGSDPL
  367-  384 (33.37/21.65)	LGLW....LATLRLV..QRERDPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.13|      23|     363|     846|     881|       5
---------------------------------------------------------------------------
  386-  429 (30.99/ 8.39)	GP.MPHLEtrlcmLLCIIPLVVgdlieeeeertpvdekDNGPTGC
  846-  869 (40.14/41.49)	GPkLPAWD.....ILEAIPFVV................DAALTAC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.78|      24|     134|     632|     665|       8
---------------------------------------------------------------------------
  634-  661 (33.98/40.63)	YLINYAPILNVLFVgiaSVDCVQIFsLH
 1085- 1108 (41.79/16.93)	YLRAYGSIRDVVFL...TEEIVSIL.MH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     278.69|      89|     461|     269|     361|       9
---------------------------------------------------------------------------
  269-  361 (138.06/99.32)	LSPEALLQLTSDSCMVLSRECKTNSQKKFQTVMSfeyLSSSAS.LCHGASHSALWI.PLDLVLEDSMDGYqVSATSAIETISGLIKTL.RAINGTS
  733-  824 (140.63/88.73)	LTPEYLLLVRNSHLMSAGNIHKDRNRRRLSEIAS...LSSPNSvFVDSFPKLKVWYrQHQACIASTLSGL.VHGTPFHQIVEGLLNMMfRKINRGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.55|      14|     932|     136|     151|      10
---------------------------------------------------------------------------
  136-  151 (23.15/20.25)	HLSNifGMPQSEPGIL
 1071- 1084 (29.40/17.98)	HLCG..GLCPVAPGIL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23698 with Med33 domain of Kingdom Viridiplantae
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