<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23694

Description Mediator of RNA polymerase II transcription subunit 16 isoform A
SequenceMNQIGGTKDPEAEPVSPSLPQPQDTPKSSDKTDSATAVVVVAAASEEQEVGEEEKPPPPPVPMEEDPVNPATVFSIRLKQPRSNLLHKMSVPELCRNFSAVSWCGKLNAIACAAETCARIPSSTANPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFIEWSPSSCPRALLIANFHGRVTIWTQPPQGPANLVHDTSCWQREHEWRQDIAVVTKWLSGVSPYRWLSSKSSAPANSKLTFEEKYLSQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPTQNGTTPKWFCTSKGLLGCGPSGIMAGDAIITDSGAMHVAGVPIVNPSTIVVWEVAPGPGNGFQVTPKTSTTCGVPPLSPPNWDGFAALAAYLFSWQDYLLSEAKQGRKQTDQNLVDAVPLYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSLQHVVLHPIFGNPTSSMGGQPPMQTVWQSKVDLSIPPTNDFKNHQSPAIGMSSDVQKVSESVSDKSKRVNFDPFDLPSDVRALARVVYSAHGGEIAIAFLRGGVHVFSGPNFTPVDNYQINVGSAIAAPAFSSTSCCSASVWHDSSKNCTILRIIRVLPPSIPISQAKANSSTWERAIAERFWWSLLVSVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSVQHRQQYGPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGKGIESALINSSALVPELWQASGETLSSIDPESMAVEPALIPSIQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGSGSNRNMVASPTQSSATPATSQGGQNGTSSSMGSAQLQTWVQGAIAKISNTTDGGSNPTPNPISGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRYINRTSDTNIQKPQSNTPAPGKVEEIAKPVSAVVKSDDGQTGRTGAKGAEEVPSGRSRLGSGNAGQGYTFEEVKVLFMMLMDLCRRTAGLQHPLPVSQVGSNNIQVRLHYIDGNYSVQPEVVEASLGPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGAPWSDPEDVDCANDTPKLVNSDPLDFSSLEHCDVYYGTHRLWPRKRRMSERDAAFGLNTSVGLGGYLGIMGSRRDVVTATWKTGLEGVWYKCVRCQRQTSAFTSPDATASPSQNDREMWWISRWVHSCPMCGGTWARVV
Length1244
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.08
Grand average of hydropathy-0.233
Instability index48.79
Isoelectric point6.16
Molecular weight134974.85
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23694
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     576.17|     167|     563|     155|     340|       1
---------------------------------------------------------------------------
  155-  340 (280.56/185.36)	RDSVQFIEWSPSSCPRAL.......LIANFHGRvTIWTQPPQGPAnLVHDTscWQREHEWrqdiavvtkwLSGVSPyrwlSSKSSAPA..NSKLTFEEKYLSQQSQTSARWPNFLCVCSVFSS.....GSVQLHWSQWPP...TQNGTTPKWfCTSKGLLG.CGPSGIMAGD..AII..............TDSGAMHVAGVPIVNPSTIVVWEVAPG..PG
  403-  471 (55.93/18.78)	.....................................................................................................................CSPVSN.....FSAYV.....SPeaaAQSAATTTW...GSGVTA.VAFDPTRAGSviAVV..............IVEGQYMSPYDPDEGPS.ITGWRV.......
  716-  907 (239.69/123.86)	RIKCRLLEGSNAQEVRAMvldmqarLLLDMLGK.GIESALINSSA.LVPEL..WQASGET..........LSSIDP....ESMAVEPAliPSIQAYVDSVLDLASHFITRLRRYASFCRTLAShavtaGSGSNRNMVASP...TQSSATP...ATSQG..GqNGTSSSM.GS..AQLqtwvqgaiakisntTDGGSNPTPN.PISGPSTFMPISINTGtfPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.67|      45|    1094|       2|     134|       2
---------------------------------------------------------------------------
   78-  122 (79.61/138.06)	LKQPRSNLLHKMSVPELCRNFSAVSWCGKLNAIACAAETCARIPS
  950-  994 (73.06/ 9.36)	IQKPQSNTPAPGKVEEIAKPVSAVVKSDDGQTGRTGAKGAEEVPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     114.80|      28|     562|     643|     670|       3
---------------------------------------------------------------------------
  643-  670 (53.68/33.86)	QAKANSSTWERAIAERFWWSLLVSVDWW
 1179- 1195 (22.83/ 9.77)	..........RDVVTATWKTGLEGV.WY
 1211- 1229 (38.29/21.84)	DATASPSQNDREM....WW.....ISRW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.16|      27|    1094|       2|      33|       5
---------------------------------------------------------------------------
    2-   33 (41.72/32.71)	NQIGGtkdPEAEPvsPSLPQPQDTPK..SSDKTD
 1102- 1130 (49.44/25.47)	NMFGA...PWSDP..EDVDCANDTPKlvNSDPLD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23694 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSGSNRNMVASPTQSSATPATSQGGQNGTSSSMG
2) MNQIGGTKDPEAEPVSPSLPQPQDTPKSSDKTDSATAVVVVAAASEEQEVGEEEKPPPPPVPMEEDPVNPATVF
3) NRTSDTNIQKPQSNTPAPGKVEEIAKPVSAVVKSDDGQTGRTGAKGAEEVPSGRSRLGS
826
1
943
859
74
1001










Molecular Recognition Features






MoRF SequenceStartStop




1) TDSATAVVVVAAA
32
44