<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23693

Description Mediator of RNA polymerase II transcription subunit 16 isoform B
SequenceMNQIGGTKDPEAEPVSPSLPQPQDTPKSSDKTDSATAVVVVAAASEEQEVGEEEKPPPPPVPMEEDPVNPATVFSIRLKQPRSNLLHKMSVPELCRNFSAVSWCGKLNAIACAAETCARIPSSTANPPFWIPIHIVIPERPTECAVFNVIADSPRDSVQFIEWSPSSCPRALLIANFHGRVTIWTQPPQGPANLVHDTSCWQREHEWRQDIAVVTKWLSGVSPYRWLSSKSSAPANSKLTFEEKYLSQQSQTSARWPNFLCVCSVFSSGSVQLHWSQWPPTQNGTTPKWFCTSKGLLGCGPSGIMAGDAIITDSGAMHVAGVPIVNPSTIVVWEVAPGPGNGFQVTPKTSTTCGVPPLSPPNWDGFAALAAYLFSWQDYLLSEAKQGRKQTDQNLVDAVPLYCSPVSNFSAYVSPEAAAQSAATTTWGSGVTAVAFDPTRAGSVIAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSLQHVVLHPIFGNPTSSMGGQPPMQTVWQSKVDLSIPPTNDFKNHQSPAIGMSSDVQKVSESVSDKSKRVNFDPFDLPSDVRALARVVYSAHGGEIAIAFLRGGVHVFSGPNFTPVDNYQINVGSAIAAPAFSSTSCCSASVWHDSSKNCTILRIIRVLPPSIPISQAKANSSTWERAIAERFWWSLLVSVDWWDAVGCTQSAAEDGIVSLNSVIAVLDADFHSLPSVQHRQQYGPSLDRIKCRLLEGSNAQEVRAMVLDMQARLLLDMLGKGIESALINSSALVPELWQASGETLSSIDPESMAVEPALIPSIQAYVDSVLDLASHFITRLRRYASFCRTLASHAVTAGSGSNRNMVASPTQSSATPATSQGGQNGTSSSMGSAQLQTWVQGAIAKISNTTDGGSNPTPNPISGPSTFMPISINTGTFPGTPAVRLIGDCHFLHRLCQLLLFCFFFRRTQLPRYINRTSDTNIQKPQSNTPAPGKVEEIAKPVSAVVKSDDGQTGRTGAKGAEEVPSGRSRLGSGNAGQGYTFEEVKVLFMMLMDLCRRTAGLQHPLPVSQVGSNNIQVRLHYIDGNYSVQPEVVEASLGPHMQRCRCCWSSFTRTRTPPSSRRVAQAEYVWCTLV
Length1103
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.08
Grand average of hydropathy-0.181
Instability index50.21
Isoelectric point6.36
Molecular weight119156.32
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23693
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     163.83|      47|     336|     427|     582|       1
---------------------------------------------------------------------------
  489-  536 (83.10/126.73)	NPTSSMGGQPPMQTvWQSKVDLSIPPTNDFKNHQSP.AIGMSSDVQKVS
  852-  899 (80.73/ 7.33)	NGTSSSMGSAQLQT.WVQGAIAKISNTTDGGSNPTPnPISGPSTFMPIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     258.83|      82|     420|     128|     405|       3
---------------------------------------------------------------------------
  194-  294 (129.22/121.60)	LVHDTscWQREHEWrqdiavvtkwLSGVSPyrwlSSKSSAPA..NSKLTFEEKYLSQQSQTSARWPNFLCVCSVFSS.....GSVQLHWSQWPPTQNGTTPkwfCTSK
  760-  848 (129.61/63.04)	LVPEL..WQASGET..........LSSIDP....ESMAVEPAliPSIQAYVDSVLDLASHFITRLRRYASFCRTLAShavtaGSGSNRNMVASPTQSSATP...ATSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.00|      37|     243|     443|     481|       5
---------------------------------------------------------------------------
  443-  481 (65.57/47.77)	SVIAVviVEGQYMS.P...YDPDEGPSITGWRVQRWE.SSLQHV
  689-  730 (52.43/31.81)	SVIAV..LDADFHSlPsvqHRQQYGPSLDRIKCRLLEgSNAQEV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.13|      12|     241|     116|     130|       7
---------------------------------------------------------------------------
  116-  130 (22.59/15.90)	TCARIPSStanPPFW
  352-  363 (28.54/12.79)	TCGVPPLS...PPNW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23693 with Med16 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GSGSNRNMVASPTQSSATPATSQGGQNGTSSSMG
2) MNQIGGTKDPEAEPVSPSLPQPQDTPKSSDKTDSATAVVVVAAASEEQEVGEEEKPPPPPVPMEEDPVNPATVF
3) NRTSDTNIQKPQSNTPAPGKVEEIAKPVSAVVKSDDGQTGRTGAKGAEEVPSGRSR
826
1
943
859
74
998










Molecular Recognition Features






MoRF SequenceStartStop




1) KTDSATAVVVVAAA
31
44