<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23656

Description Mediator of RNA polymerase II transcription subunit 15a isoform A
SequenceMGSYGIQIVVSRVVFNSAHCVCTSLDSTAQTGQSSGGDWQEEVYQKIKSMKESYLPELNEMYQKIASKLQQIALCANQVITLPERESFIVFVFTQIILTVFNLVSFHYQHDSLPQQPKSDQLEKLKVFKMMLERIITFLQVSKSNISPNFKEKLNSYEKQIINFINTNRPRKNMPGHLPSPHMHSMSQSQPQVTQVQSHENQMNSQLQTTNMQGSVATMQQNNMAAMQHNSLSGVSTAQQSKMNSMQPSTNLDSGPGNAVNSLQQVPVSSLQQNPVSAPQLTNVNSLSSQAGVNVVQPNHNPLQPGSSMLQHQQLKQQQEQQMLQNQQLKQQYQRQLIQRKQQQILQQQQQQQQLHQTAKQQLPAQLPTHQIQQLHQMNDANDIKMRQGISVKPGVFQQPLTSSQRSTYPHQQMKGSPFPVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVATPLQSANSPFMVPTPSPPLAPSPMPGDSEKPISGVSSISNAANIGYQLTGGAAAPAQSLAIGTPGISASPLLAEFTGPDGAHGNALAPTSGKLTVTEQPIERLIKAVKSMSPKALSSAVSDIGSVVSMNDRIAGSAPGNGSRAAVGEDLVAMTNCRLQARNFITQDGANGTRRMKRYTNATPLNVVSSPGSMNDSIKQLTAEASDLDSTATSRFKMPRIEANHSLLEEIREVNQRLIDTVVDISNEEVDPTAAAAAAEGTEGTIVKCSYNAVALGPSLKSQYASAQMSPIQPLHLLVPTNYPNCSPILLDKFPVESSKENEDLSVKAKSRFSISLRSLSQPMSLGEIARTWDVCARIVISEHAQQSGGGSFSSKYGTWENCLTT
Length839
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.04
Grand average of hydropathy-0.468
Instability index59.28
Isoelectric point8.79
Molecular weight91427.21
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23656
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.05|      16|      16|     327|     342|       1
---------------------------------------------------------------------------
  334-  351 (21.78/ 6.28)	QRQLIQRKQQQIlqQQQQ
  364-  379 (28.12/10.01)	PAQLPTHQIQQL..HQMN
  431-  446 (26.15/ 8.85)	SPQIPQHSSPQV..DQQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     225.27|      45|      54|     186|     233|       2
---------------------------------------------------------------------------
  186-  228 (71.11/27.45)	...........MSQSQPQVTQVQS.HENQM...NSQLQTTNM.QGSVATMQQNNMAAMQ
  232-  280 (55.36/23.27)	LSgvstaqqskMNSMQPS.TNLDSgPGNAV...NS.LQ.....QVPVSSLQQNPVSAPQ
  281-  327 (43.88/12.12)	LT.....nvnsLS.SQAGVNVVQP.NHNPLqpgSSMLQHQQLkQQQEQQMLQNQ.....
  391-  425 (54.92/19.50)	.............SVKPGVFQ.QP.LTSSQ...RSTYPHQQM.KG..SPF...PVSSPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     110.44|      25|      26|     502|     526|       3
---------------------------------------------------------------------------
  466-  487 (33.51/15.16)	MV....PTPSPPLA..PSPmPGDSEKPI
  502-  526 (42.03/20.89)	QLTGGAAAPAQSLA..IGT.PGISASPL
  529-  555 (34.90/16.09)	EFTGPDGAHGNALAptSGK.LTVTEQPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     110.52|      36|     116|     657|     692|       4
---------------------------------------------------------------------------
  657-  692 (60.72/33.55)	EASDLDSTATSRFKMP..RIEANHSLLEEIR..EVNQRLI
  774-  813 (49.81/26.38)	ENEDLSVKAKSRFSISlrSLSQPMSLGEIARtwDVCARIV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.59|      21|      24|     128|     150|      10
---------------------------------------------------------------------------
  128-  148 (35.67/30.00)	FKMMLERIITFLQVSKS..NI.....SP
  154-  181 (26.93/12.87)	LNSYEKQIINFINTNRPrkNMpghlpSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.87|      23|      85|       7|      34|      14
---------------------------------------------------------------------------
    7-   34 (30.25/30.14)	QIVVSrvVFN..SAHcvcTSLDSTAQTGQS
   95-  119 (39.63/21.61)	QIILT..VFNlvSFH...YQHDSLPQQPKS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23656 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NFITQDGANGTRRMKRYTNATPLNVVSSPGSM
2) NRPRKNMPGHLPSPHMHSMSQSQPQVTQVQSHENQMNSQLQTTNMQGSVATMQQNNMAAMQHNSLSGVSTAQQSKMNSMQPSTNLDSGPGNAVNSLQQVPVSSLQQNPVSAPQLTNVNSLSSQAGVNVVQPNHNPLQPGSSMLQHQQLKQQQEQQMLQNQQLKQQY
3) RKQQQILQQQQQQQQLHQTAKQQLPAQLPTHQIQQLHQMNDANDIKMRQGISVKPGVFQQPLTSSQRSTYPHQQMKGSPFPVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVATPLQSANSPFMVPTPSPPLAPSPMPGDSEKPISGVS
616
168
340
647
333
491










Molecular Recognition Features






MoRF SequenceStartStop




NANANA