<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23655

Description Mediator of RNA polymerase II transcription subunit 15a isoform B
SequenceMGSYGIQIVVSRVVFNSAHCVCTSLDSTAQTGQSSGGDWQEEVYQKIKSMKESYLPELNEMYQKIASKLQQHDSLPQQPKSDQLEKLKVFKMMLERIITFLQVSKSNISPNFKEKLNSYEKQIINFINTNRPRKNMPGHLPSPHMHSMSQSQPQVTQVQSHENQMNSQLQTTNMQGSVATMQQNNMAAMQHNSLSGVSTAQQSKMNSMQPSTNLDSGPGNAVNSLQQVPVSSLQQNPVSAPQLTNVNSLSSQAGVNVVQPNHNPLQPGSSMLQHQQLKQQQEQQMLQNQQLKQQYQRQLIQRKQQQILQQQQQQQQLHQTAKQQLPAQLPTHQIQQLHQMNDANDIKMRQGISVKPGVFQQPLTSSQRSTYPHQQMKGSPFPVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVATPLQSANSPFMVPTPSPPLAPSPMPGDSEKPISGVSSISNAANIGYQLTGGAAAPAQSLAIGTPGISASPLLAEFTGPDGAHGNALAPTSGKLTVTEQPIERLIKAVKSMSPKALSSAVSDIGSVVSMNDRIAGSAPGNGSRAAVGEDLVAMTNCRLQARNFITQDGANGTRRMKRYTNATPLNVVSSPGSMNDSIKQLTAEASDLDSTATSRFKMPRIERLYMKMHCRWGKGKEITQQTRIQVGQGERNKHVANHSLLEEIREVNQRLIDTVVDISNEEVDPTAAAAAAEGTEGTIVKCSYNAVALGPSLKSQYASAQMSPIQPLHLLVPTNYPNCSPILLDKFPVESSKENEDLSVKAKSRFSISLRSLSQPMSLGEIARTWDVCARIVISEHAQQSGGGSFSSKYGTWENCLTT
Length834
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.04
Grand average of hydropathy-0.569
Instability index60.90
Isoelectric point9.22
Molecular weight91009.69
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23655
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.55|      17|      17|     289|     305|       1
---------------------------------------------------------------------------
  289-  305 (29.60/11.91)	QQLKQQYQRQLIQRKQQ
  335-  351 (22.95/ 7.59)	QQLHQMNDANDIKMRQG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.06|      27|      28|      85|     112|       2
---------------------------------------------------------------------------
   61-   91 (33.94/16.27)	MYQKIASKLQQHDSlPQQPKSdqlEKLKVFK
   93-  120 (40.12/27.20)	MLERIITFLQVSKS.NISPNF..kEKLNSYE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     178.96|      28|      29|     170|     197|       3
---------------------------------------------------------------------------
  145-  182 (33.82/11.30)	MHSMSQSQ.............PQVT...QVqshenqmnsqlQTTN...MQGSVA.TMQ
  183-  201 (25.48/ 6.67)	QNNMAAMQH............NSLS...GV........................sTAQ
  202-  234 (25.46/ 6.66)	QSKMNSMQPstnldsgpgnavNSLQ...QV...........P..........VS.SLQ
  235-  266 (26.77/ 7.39)	QNPVSAPQL.........tnvNSLSsqaGV...............nvvQPNHNP..LQ
  310-  333 (38.08/13.67)	Q....QQQQ............QQLH...QT...........AKQQ...LPAQLP.THQ
  360-  381 (29.33/ 8.81)	QQPLTSSQR............ST......Y...........PHQQ...MKGS...PF.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     212.47|      60|      72|     421|     482|       4
---------------------------------------------------------------------------
  382-  417 (30.76/11.31)	............PVSSPQLlqAT....SPqIPQH...SS...................PQVDQQNHLPS....LT.KVA........
  418-  478 (103.15/61.42)	TPLQSAnSPFMVPTPSPPL..AP....SP.MPGD...SEKPI................SGVSSISNAANIGYQLTGGAAAPAQSLAI
  480-  562 (78.56/45.41)	TPGISA.SPLLAEFTGPDG..AHgnalAP.TSGKltvTEQPIerlikavksmspkalsSAVSDIGSVVSMNDRIAGSAPGNGSRAAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.24|      13|     147|     619|     631|       5
---------------------------------------------------------------------------
  619-  631 (22.63/16.68)	EASDLDSTATSRF
  769-  781 (22.61/16.65)	ENEDLSVKAKSRF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23655 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) IINFINTNRPRKNMPGHLPSPHMHSMSQSQPQVTQVQSHENQMNSQLQTTNMQGSVATMQQNNMAAMQHNSLSGVSTAQQSKMNSMQPSTNLDSGPGNAVNSLQQVPVSSLQQNPVSAPQLTNVNSLSSQAGVNVVQPNHNPLQPGSSMLQHQQLKQQQEQQMLQNQQLKQQY
2) NFITQDGANGTRRMKRYTNATPLNVVSSPGSMNDSIKQLTAEAS
3) RKQQQILQQQQQQQQLHQTAKQQLPAQLPTHQIQQLHQMNDANDIKMRQGISVKPGVFQQPLTSSQRSTYPHQQMKGSPFPVSSPQLLQATSPQIPQHSSPQVDQQNHLPSLTKVATPLQSANSPFMVPTPSPPLAPSPMPGDSEKPISGVS
123
578
302
295
621
453










Molecular Recognition Features






MoRF SequenceStartStop




NANANA