<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP23653

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDNNNWRPNQGTEANMDTSDWRGGLPHESRQRIVNKMSKDPWRAESLEGEITLGLRFTKFNHGIVDPSIPAKRSMAKITLYFSFDEMFPAIRDLNPIQKSLNRVPLDLSFFTTAKASPRATSAAFSLCYTAFGSISATVHLFVPLLPSSGRNIGYSNPSYEFSPPPNPRMDTLKRHLPVSVQEGLHELQKIAQRFEEKIFTAATSQSDYLRKISLKMLTMETKSQGSMAPNLPPNQGGPSNKPPDPGLGIPPQVHNPGQQHPIPMSNQTPNRQQLLPQNIQNSIASQPSNIAQAPIQNVGQNNPNVQNIPGQNSVGSTIGQNANMQNMFPGSQRQIQGRQQVVPQQQQQQSQNSQQYIYQQQMQQQLIRQKLQQQQQQQQQQQNLLQSNQLQSSQQPSIQTSTVMQQPSMMQTSLPSIQHNQQSNNQQQSTQSVLQQHSQVIRQQQPQQTSIIHQQQTPMTQQSILPPQQQQQQQQQLMGAQANAPNMHHTQILGSQNNVGDLQQPQRLLTQQNNLSNLQQQQLINQQNNLSNMHQQLGNNVPGLQPQQVLGPQPGNSGMQTSQHSAHVLQQSQVPIQQQSQQNASNLLPSQVQQSQPQAPQQQLMPQIQSQPAQLQQQLGLQQQPNPLQRDMQQRLQASGPLLQQSNVLDQQKQLYQSQRPLPETSSKYKNISLKFSLKSELYYGIRAGFEPWIYSLPSVHNNSSPPSRLTPIHAEPVSAFPLAASVIFSHTISEKWM
Length739
PositionTail
OrganismGlycine soja (Wild soybean)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fabales> Fabaceae> Papilionoideae> 50 kb inversion clade> NPAAA clade> indigoferoid/millettioid clade> Phaseoleae> Glycine> Glycine subgen. Soja.
Aromaticity0.05
Grand average of hydropathy-0.871
Instability index77.04
Isoelectric point9.86
Molecular weight83017.91
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP23653
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     588.81|      92|      95|     358|     449|       2
---------------------------------------------------------------------------
  151-  198 (54.19/ 7.84)	................................RNIG..YSN................PSYEFSP.P.P....................NP..RMdtLKRHLP.................VSVQEGLHEL.QK.IAQRFEEK
  199-  290 (109.91/24.77)	IFTAA..TsQSDYLRKislkMLTMETKSQGSMAPNL..PPN.......QGG..PSNKPP...DPGL.G....................IP..P....QVHNPGQQHpipmsNQTPNRQQ.....LLPQNIQN.SIASQPSN
  358-  449 (174.34/44.34)	IYQQQ..M.QQQLIRQ....KLQQQQQQQQQQQNLL..QSN.......QLQ..SSQQPSIQTSTVM.Q....................QP..SM..MQTSLPSIQH.....NQQSNNQQQSTQSVLQQHSQV.IRQQQPQQ
  453-  520 (65.13/11.16)	IHQQQtpM.TQQSI.......LPPQQQQQQQQQ.LMgaQANapnmhhtQIL..GSQN...NVGD.L.Q....................QP..QR..LLT.....QQ.....NNLSNLQ.......................
  521-  577 (58.79/ 9.23)	.........QQQLI...............NQQNNL....SN.......MHQqlGNNVPGLQPQQVLgP....................QPgnSG..MQTS....QH........SAH.......VLQQ.SQVpI.......
  578-  628 (70.16/12.69)	........................QQQSQQNASNLL..PS........QVQ..QS.QPQAPQQQLM.......................P..Q...IQ.SQPA.QL.....QQQLG.........LQQ.......QPNP..
  629-  706 (56.28/ 8.47)	.LQRD..M.Q.....Q....RLQASGPLLQQSNVLD..QQK.......QLY..QSQRPLPETSSKY.KnislkfslkselyygiragfEP..WI..Y..SLPSV.H.....NNSS..........................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.28|      12|      18|     299|     311|       3
---------------------------------------------------------------------------
  299-  311 (20.89/12.80)	VGQnNPNVQNI.PG
  319-  331 (21.39/ 8.47)	IGQ.NANMQNMfPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     101.40|      24|      24|      51|      74|       5
---------------------------------------------------------------------------
   51-   74 (42.77/25.62)	ITLGLRFTKFN......HGIVDPSIPAKRS
   78-  100 (38.29/22.24)	ITLYFSFDEMF......PAIRDLN.PIQKS
  123-  147 (20.34/ 8.70)	AAFSLCYTAFGsisatvHLFV.PLLP....
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP23653 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MDNNNWRPNQGTEANMDTSDWRGGLPHESR
2) METKSQGSMAPNLPPNQGGPSNKPPDPGLGIPPQVHNPGQQHPIPMSNQTPNRQQLLPQNIQNSIASQPSNIAQAPIQNVGQNNPNVQNIPGQNSVGSTIGQNANMQNMFPGSQRQIQGRQQVVPQQQQQQSQNSQQ
3) QNLLQSNQLQSSQQPSIQTSTVMQQPSMMQTSLPSIQHNQQSNNQQQSTQSVLQQHSQV
4) QQPQQTSIIHQQQTPMTQQSILPPQQQQQQQQQLMGAQANAPNMHHTQILGSQNNVGDLQQPQRLLTQQNNLSNLQQQQLINQQNNLSNMHQQLGNNVPGLQPQQVLGPQPGNSGMQTSQHSAHVLQQSQVPIQQQSQQNASNLLPSQVQQSQPQAPQQQLMPQIQSQPAQLQQQLGLQQQPNPLQRDMQQRLQASGPLLQ
1
220
383
445
30
356
441
645










Molecular Recognition Features






MoRF SequenceStartStop




NANANA